Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors by Daniel J. Merk, Foteini Tsiami, Sophie Hirsch, Bianca Walter, Lara A. Haeusser, Jens D. Maile, Aaron Stahl, Mohamed A. Jarboui, Anna Lechado-Terradas, Franziska Klose, Sepideh Babaei, Jakob Admard, Nicolas Casadei, Cristiana Roggia, Michael Spohn, Jens Schittenhelm, Stephan Singer, Ulrich Schüller, Federica Piccioni, Nicole S. Persky, Manfred Claassen, Marcos Tatagiba, Philipp J. Kahle, David E. Root, Markus Templin, Ghazaleh Tabatabai

“…Results We here use a functional genomics approach to identify genetic dependencies in ATRT, validate selected hits using a functionally instructed small molecule drug library, and observe preferential activity in ATRT cells without subgroup-specific selectivity. …”
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The Role of Social Media in Promoting Volunteer Initiatives and Shaping Communities by Iefimova Ganna V., Pashchenko Kseniia O.

“…The methodological basis of the research is an interdisciplinary approach that combines content analysis of social platforms, study of successful volunteer initiatives, and analysis of literary sources. An analysis of the functions of various social media in the context of informing, engaging the audience, and building trust has been carried out. …”
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APPLICATION OF THE SPECTROMETRIC METHOD FOR CALCULATING THE DOSE RATE FOR CREATING CALIBRATION HIGHLY SENSITIVE INSTRUMENTS BASED ON SCINTILLATION DETECTION UNITS by R. V. Lukashevich, G. A. Fokov

“…The results of the calculation function G(E) for the detection unit on the basis of NaI(Tl) detector (Ø40 mm, h = 40 mm) to use it as a comparator for kerma rate in the air certification of low intenseе photon radiation fields.…”
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Hybrid Framework To Exclude Similar and Faulty Test Cases In Regression Testing by Muhammad Asim Siddique, Wan M.N. Wan-Kadir, Johanna Ahmad, Noraini Ibrahim

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Accelerated Selective Electrooxidation of Ethylene Glycol and Inhibition of C–C Dissociation Facilitated by Surficial Oxidation on Hollowed PtAg Nanostructures via In Situ Dynamic... by Yuhan Li, Qingliang Liao, Peiyi Ji, Sheng Jie, Chunjie Wu, Kunyi Tong, Minghui Zhu, Chenhao Zhang, Hui Li

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The ANFIS-RSM based multi-objective optimization and modelling of ultrasound-assisted extraction of polyphenols from jamun fruit (Syzygium cumini) by Mohammad Ganje, Somayyeh Gharibi, Fatemeh Nejatpour, Maryam Deilamipour, Kimia Goshadehrou, Sahra Saberyan, Gholamreza Abdi

“…For each of the six process-solver conditions, optimal ANFIS models were determined by analyzing the number and type of input membership functions, the output membership function, and the selected optimization and defuzzification methods, based on the highest correlation between actual and predicted data, along with the lowest error rates. …”
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Optimization and Simulation of Flat Area Sites Based on Probability Matching and Transfer Intensity Using Remote Sensing Precipitation by Chen Yu, Huaiyong Shao, Xingchuan Yang, Gang Liu, Qi Xin, Jiaming Gu

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A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles by Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger

“…Subsequently, adding gold nanoparticles functionalized with SERS probes and aptamers enabled the detection of tau in EVs using SERS. …”
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Research on monthly runoff prediction model considering secondary decomposition of multiple fitness functions and deep learning by Zhongfeng Zhao, Xueni Wang, Hua Jin, Jie Zheng

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Enrichment of bread with encapsulated probiotics as a functional product containing bioactive compounds: Principles, outcomes, and challenges by Samira Beikzadeh, Alireza Sadeghi, Arezou Khezerlou, Elham Assadpour, Seid Mahdi Jafari

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Multi-omics insights into functional alterations of the liver in growth-retarded offspring: transcriptomic, epigenetic and metabolomic profiles by Qun Lan, Sui Liufu, Xin Xu, Bohe Chen, Wenwu Chen, Kaiming Wang, Caihong Liu, Lanlin Xiao, Xiaolin Liu, Lei Yi, Jingwen Liu, Qiuchun Deng, Haiming Ma, Meng Kang

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Loss of OprD function is sufficient for carbapenem-resistance-only but insufficient for multidrug resistance in Pseudomonas aeruginosa by Maofeng Wang, Yuxiao Zhang, Fengyan Pei, Ying Liu, Yan Zheng

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Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study. by Carolyn A Carr, Daniel J Stuckey, Jun Jie Tan, Suat Cheng Tan, Renata S M Gomes, Patrizia Camelliti, Elisa Messina, Alessandro Giacomello, Georgina M Ellison, Kieran Clarke

“…<h4>Aims</h4>Endogenous cardiac progenitor cells, expanded from explants via cardiosphere formation, present a promising cell source to prevent heart failure following myocardial infarction. …”
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Combining Open-Source Machine Learning and Publicly Available Aerial Data (NAIP and NEON) to Achieve High-Resolution High-Accuracy Remote Sensing of Grass–Shrub–Tree Mosaics by Brynn Noble, Zak Ratajczak

“…NAIP underperformed in detecting evergreen trees (52–78% vs. 83–86% accuracy with NEON). …”
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Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome by Jun-Jie Li, Qing Yao, Ming Dong, Yan Wang, Ye Xiu, Zhi-Xin Wu, Xiao-Mei Zhao, Yin-Kang Wang, Xian-Ling Wang, Yu-Xuan Tian, Xiao-He Xiao, Zhao-Fang Bai

“…Materials and Methods: The activation of the cGAS-STING pathway was modeled in bone marrow-derived macrophages (BMDMs) and human leukemia monocytic cell line (THP-1) cells in vivo, and the expression of type I IFN-related genes and pro-inflammatory cytokines was detected after DG pretreatment. Next, we examined the effect of DG on STING downstream signaling events, such as STING oligomerization and functional STING signalosome formation. …”
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Therapeutic Role of Green Tea on Human Body Function, Some Diseases and Weight loss: A Review by Sawsan Al-Harbi, Fouad Gatea

“…Therapeutic role of green tea on human body function, some diseases and weight loss: A review. …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…Information required to populate the models included the prevalence of lung nodules, risk of lung cancer with different nodule sizes, sensitivity and specificity for nodule detection, nodule type and size distributions in different population, resource use, costs and utilities. …”
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Dynamics of Population Patch Distribution by Alexander N. Kirillov, Inna V. Danilova

“…The problem of selection by the patch population in the absence of information on the utility of the patch, that is, the volume of its energy resources, is considered. …”
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Karbon dots (C-dots) dari Bahan Hayati untuk Deteksi Logam Berat by Cut Navita Rahmi, Sri Sugiarti, Alvian Dea Yuliani

“…This study aims to review carbon nanoparticles derived from natural sources for detecting heavy metals. C-dots derived from biological sources have been widely studied as selective heavy metal detection. …”
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Marker weighting improves single-step genomic prediction reliabilities of udder health traits in Nordic Red and Jersey dairy cattle populations by Arash Chegini, Ismo Strandén, Emre Karaman, Terhi Iso-Touru, Jukka Pösö, Gert P. Aamand, Martin H. Lidauer

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