High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

Get full text

Linking soil microbial genomic features to forest-to-pasture conversion in the Amazon by Andressa M. Venturini, Júlia B. Gontijo, Louis Berrios, Jorge L. Mazza Rodrigues, Kabir G. Peay, Siu M. Tsai

“…These abundant members of the microbial communities diverged across forests and pastures in terms of taxonomic and functional traits. Forest conversion favors organisms with specific genomic features — increased GC content, genome size, and gene number — selecting for microorganisms that can thrive under altered conditions. …”
Get full text

Pretest probability of coronary artery disease as a factor for optimizing invasive diagnostics in routine clinical practice by M. A. Simonyan, T. Yu. Kalyuta, E. N. Genkal, O. M. Posnenkova, V. I. Gridnev

“…In 2017-2019, the number of detected CAD cases and proportion of men increased. …”
Get full text

Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia by Jinli Yao, Yanqing Qin, Dongping Tu, Yumei Huang, Liuguan Liang, Wenhui Cai, Mingli Huang, Xiaoqi Zhu, Xinling Lao

“…A total of 91 differential metabolites were detected, belonging to 10 alkaloids, among which pyrrolizidine alkaloids accounted for 13%. …”
Get full text

Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective prop... by Wenyun Xiong, Lixia Guo, Yiting Zhang, Shurui Li, Zihuan Wu, Shengbao Cai

Get full text

Introducing the English EmpaToM task: A tool to assess empathy, compassion, and theory of mind in fMRI studies by Dorottya Lantos, Celeste Costa, Matthew Briglia, Pascal Molenberghs, Philipp Kanske, Tania Singer

Get full text

Levels of amino acids and homoarginine in the venous basins of the brain and the heart muscle in patients with ischemic heart disease by N. S. Molchan, T. Yu. Reypol'skaya, T. F. Subbotina, A. A. Zhloba, Yu. S. Polushin

“…Under the conditions of circulatory disorders and coronary heart disease (CHD), amino acids acquire additional value as a source of intermediates of Krebs cycle, participating in cell energetics. …”
Get full text

Enzymatic system of glucose metabolism in Gluconobacter oxydans strain DHA3-9 by Li Qianyan, Lu Xiangfeng, Zhang Pengcheng, Sun Lingyan, Liu Yu, Ma Xiaohang

“…Pyruvate and acetate were detected in the products of mutant whereas none of such products were found in wild type culture. …”
Get full text

ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans. by Lina Zhao, Lorenz A Fenk, Lars Nilsson, Niko Paresh Amin-Wetzel, Nelson Javier Ramirez-Suarez, Mario de Bono, Changchun Chen

“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
Get full text

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. by Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota

“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
Get full text

Experimental Study of Coherent Collaborative Processing Method in Distributed Automotive Radar by A. A. Kuzin, S. E. Kuznetsov, A. V. Miakinkov, R. S. Fadeev, S. A. Shabalin

“…Intelligent driver assistance systems are increasingly employing radar systems to detect, resolve, and track various classes of targets. …”
Get full text

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
Get full text

A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…Wit, a second Type II receptor, shows a markedly different behavior, with the protein detected on all membrane regions but enriched at the apical side. …”
Get full text

Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
Get full text

Pollution Characteristics and Water Quality Status of Water Storage Pond in Xianyang City of Shaanxi Province by Zhou Fuyu, Gao Zhaoliang, Zhang Shuai, Li Yonghong, Sun Guanfang, Lou Yongcai, Ai Jianwei, Liu Wenbo

“…Treatment methods suitable for the rural environment should be selected according to the characteristics of water pollution.…”
Get full text

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence by Changge Guan, Marcelo D. T. Torres, Sufen Li, Cesar de la Fuente-Nunez

“…From these, we identified 386 candidates that are structurally and functionally distinct from known antimicrobial peptides. …”
Get full text

Recent Advances and Challenges in the Production of Hydroxylated Natural Products Using Microorganisms by Chang Sun, Rumei Zeng, Tianpeng Chen, Yibing Yang, Yi Song, Qiang Li, Jie Cheng, Bingliang Liu

“…Hydroxylation reaction is a significant source of structural diversity in natural products (NPs), playing a crucial role in improving the bioactivity, solubility, and stability of natural product molecules. …”
Get full text

The association between serum albumin–globulin ratio and overactive bladder in American adults: a cross-sectional study by Yuan-Zhuo Du, Jia-Hao Liu, Fu-Chun Zheng, Qiang Zhou, Ju Guo

“…However, despite its widely studied correlations in numerous health fields, the link between AGR and Overactive Bladder (OAB) is still not completely comprehended. Methods Data were sourced from the National Health and Nutrition Examination Survey (NHANES) database, selecting adult samples spanning from 2007 to 2018. …”
Get full text

DistB-Condo: Distributed Blockchain-Based IoT-SDN Model for Smart Condominium by Anichur Rahman, Md. Jahidul Islam, Ziaur Rahman, Md. Mahfuz Reza, Adnan Anwar, M. A. Parvez Mahmud, Mostofa Kamal Nasir, Rafidah Md. Noor

“…Condominium network refers to intra-organization networks, where smart buildings or apartments are connected and share resources over the network. Secured communication platform or channel has been highlighted as a key requirement for a reliable condominium which can be ensured by the utilization of the advanced techniques and platforms like Software-Defined Network (SDN), Network Function Virtualization (NFV) and Blockchain (BC). …”
Get full text

Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
Get full text