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2421
A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro
Published 2024-12-01“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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2422
Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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2423
Strategi Komunikasi PT Jasa Raharja Cabang D.I. Yogyakarta dalam Program Millennial Road Safety
Published 2022-10-01“…Informants in this study were selected using a purposive sampling te chnique, and there were two primary informants selected, public relations officer and PKBL division at PT Jasa Raharja Branch of Special Region of Yogyakarta. …”
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2424
Photonics-Aided THz Integrated Sensing and Communication System Based on a Subcarrier-Chirp Inter-Embedded Waveform
Published 2025-01-01“…Simultaneously, multi-user detection with an 8-mm ranging resolution is also realized. …”
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2425
IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images
Published 2025-05-01“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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2426
Optimisation of bioaerosol sampling using an ultralight aircraft: A novel approach in determining the 3-D atmospheric biodiversity
Published 2024-10-01“…Moreover, biomonitoring campaigns often take place in urban environments, although sources can be located outside cities’ borders with ampler vegetation. …”
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2427
Rapid flips between warm and cold extremes in a warming world
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2428
Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1α Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
Published 2025-04-01“…<b>Methods:</b> Consequently, we used drug design and molecular simulation techniques to screen phytochemical databases, including traditional Chinese and African medicine sources, for compounds that could disrupt the p300/HIF-1 interaction. …”
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2429
TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery
Published 2024-12-01“…Owing to the poor regenerative capabilities of endogenous oligodendrocyte precursor cells (OPCs) following SCI, there is a growing interest in alternative sources, such as human umbilical cord mesenchymal stem cells (HUCMSCs). …”
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2430
Research Progress on the Effect of Dissolved Organic Matter on the Environmental Behavior of Cadmium in Environmental Remediation
Published 2025-05-01“…The various active functional groups contained in DOM, such as carboxyl, hydroxyl, and phenolic groups, are ligands and migration carriers for many heavy metals in the environment. …”
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2431
WEB SERVICE OF WORKS PLANNING USING NETWORK GRAPH
Published 2022-05-01“…During the study, a set of theoretical, empirical, and modeling methods were applied, in particular: systematic analysis of scientific and methodological sources, the results of domestic and foreign experience on the problem, review of existing software to determine the problem solution state and select development tools of web service, analysis of methods and technologies network graphs construction, generalization of information on the problem. …”
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2432
Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage
Published 2025-02-01“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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2433
Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica
Published 2016-03-01“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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2436
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay
Published 2025-10-01“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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2437
Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria
Published 2024-09-01“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
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2438
Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study
Published 2025-03-01“…Larger prospective, controlled trials are necessary to confirm these findings and to refine patient selection and technique optimization.…”
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2439
Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System
Published 2025-06-01“…We also obtained secondary data from local government sources in East Kalimantan. Data were processed using qualitative descriptive analysis, gender, and SWOT analysis. …”
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2440
Accumulation of long-chain unsaturated fatty acids in the airway inflammatory microenvironment drives eosinophil etosis and corticosteroid resistance
Published 2025-05-01“…Functional analyses were performed on purified eosinophils. …”
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