Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…Phase 2 – realist synthesis: Empirical and grey literature, together with online discussion boards, social media sources and blogs were used to create initial programme theories regarding service architecture. …”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Secondary outcomes included: unplanned 60- and 90-day hospital re-admissions; quality of transition; health-related quality of life (EuroQol-5 Dimensions, five-level version); and self-reported healthcare resource use. Data sources National Health Service Secondary Use Services data and Hospital Episodes data for work package 2 and routinely recorded National Health Service acute trust hospital data on re-admissions for work packages 5 and 6. …”
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Finding RB/Rpi-blb1/Rpi-sto1-like sequences in conventionally bred potato varieties by O. Y. Antonova, N. S. Klimenko, Z. Z. Evdokimova, L. I. Kostina, T. A. Gavrilenko

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Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China by Jin Zheng, Yusheng Lu, Peizhi Xu, Kaizhi Xie, Changmin Zhou, Yaying Li, Haoyang Geng, Qianyuan Wang, Wenjie Gu

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Whole-genome sequencing and genomic analysis of four Akkermansia strains newly isolated from human feces by Wenjing Lu, Biqing Zha, Jie Lyu, Chenxi LingHu, Jing Chen, Sisi Deng, Xiangling Zhang, Liang Li, Guoqing Wang

“…Two annotated regions of secondary metabolite biosynthesis genes, both belonging to Terpene, were detected using the antiSMASH online tool.ConclusionThese findings indicate that the four Akkermansia isolates, which belong to a phylogroup distinct from the model strain DSM 22959, exhibit lower genetic risk and may serve as potential probiotic resources for future research.…”
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Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…The material was a whole blood sample obtained from a woman with clinical manifestations of hereditary angioedema without a decrease in the levels and function of the C1 inhibitor. The research methods included whole exome sequencing, bioinformatic analysis of the KNG1 gene mutation using a number of databases and web resources. …”
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In situ, modeled, and earth observation monitoring of surface water availability in West African rangelands by Kimberly Slinski, Kimberly Slinski, Gabriel B. Senay, Alkhalil Adoum, Shraddhanand Shukla, Amy McNally, James Rowland, Erwann Fillol, Soni Yatheendradas, Soni Yatheendradas, Chris Funk, Andrew Hoell, Michael Jasinski

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Assessment of the capacity of health facilities in preventing and managing non-communicable diseases in selected regions of Somaliland by Opeolu O. Ojo, Omar O Hersi, Ayodele A Falobi, Nura Ali, Lawrence Tan, Yusuf A. Ali

“…The impact of location, level of care provided and source of funding on the capacity of hospitals was assessed. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

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