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    Genomics and integrative clinical data machine learning scoring model to ascertain likely Lynch syndrome patients by Ramadhani Chambuso, Takudzwa Nyasha Musarurwa, Alessandro Pietro Aldera, Armin Deffur, Hayli Geffen, Douglas Perkins, Raj Ramesar

    Published 2025-05-01
    “…Annovar, Intervar, Variant Effect Predictor (VEP), and OncoKB software tools were used to functionally annotate and interpret somatic variants detected. …”
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  3. 1343

    PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. by Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton

    Published 2009-07-01
    “…Therefore, computational methods which, given a set of 3D coordinates, can automatically identify and describe channels in transmembrane proteins are key tools to provide insights into how they function.Herein we present PoreWalker, a fully automated method, which detects and fully characterises channels in transmembrane proteins from their 3D structures. …”
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  4. 1344

    Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

    Published 2025-05-01
    “…Design Work package 1: we developed and validated a new instrument to provide improved detection of mental health and behavioural problems in autistic people from childhood through to adult life. …”
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  5. 1345

    Fast-timing spectroscopy with the ν-ball2 spectrometer by Pascu S., Hiver C., Podolyák Zs., Regan P.H., von Tresckow M., Wilson J.N.

    Published 2025-01-01
    “…These observables and their corresponding transition probabilities are key fingerprints for the structure of atomic nuclei, as they are sensitive to small components of the wave function. Neutron-rich nuclei have been populated in a two-step fission-induced experiment. …”
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  6. 1346

    Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity by Fayura O., Starikovych M., Abrahamovych O., Abrahamovych M., Stoyka R., Kit Yu.

    Published 2019-10-01
    “…Since the protein content of human urine is closely related to the peculiarity of the functioning of biological systems, its qualitative and quantitative characteristics are promising markers for control of various processes in organism. …”
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  7. 1347

    Artificial intelligence analysis in cyber domain: A review by Liguo Zhao, Derong Zhu, Wasswa Shafik, S Mojtaba Matinkhah, Zubair Ahmad, Lule Sharif, Alisa Craig

    Published 2022-04-01
    “…The results in this study demonstrated that using a proportional collection of instances trained with the deep learning algorithm, a classified data set can accurately detect suspicious behavior. This method permits for the allocation of multiple log source types through a sliding time window and provides a scalable solution, which is a much-needed function.…”
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  8. 1348

    Cortical layer-specific abnormalities in auditory responses in a mouse model of Fragile X Syndrome by Katrina E. Deane, Devin K. Binder, Khaleel A. Razak

    Published 2025-08-01
    “…Sensory sensitivity and temporal processing deficits in the auditory domain will affect development of language and cognitive functions. The mouse model for FXS, Fmr1 KO, has shown remarkably similar auditory processing phenotypes to patients with FXS. …”
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  11. 1351

    Comparative Analysis of Transcriptomes from Secondary Reproductives of Three Reticulitermes Termite Species. by Franck Dedeine, Lucy A Weinert, Diane Bigot, Thibaut Josse, Marion Ballenghien, Vincent Cahais, Nicolas Galtier, Philippe Gayral

    Published 2015-01-01
    “…A total of 18,323 orthologous gene clusters were detected. Functional annotation and taxonomic assignment were performed on a total of 41,287 predicted contigs in the three termite species. …”
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  12. 1352

    Optimizing maize germination forecasts with random forest and data fusion techniques by Lili Wu, Yuqing Xing, Kaiwen Yang, Wenqiang Li, Guangyue Ren, Debang Zhang, Huiping Fan

    Published 2024-11-01
    “…Traditional methods for detecting seed germination rates often involve lengthy experiments that result in damaged seeds. …”
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  13. 1353

    Community, facility and individual level impact of integrating mental health screening and treatment into the primary healthcare system in Sehore district, Madhya Pradesh, India by Crick Lund, Vikram Patel, Rahul Shidhaye, Emily Baron, Vaibhav Murhar, Sujit Rathod, Azaz Khan, Abhishek Singh, Sanjay Shrivastava, Shital Muke, Ritu Shrivastava

    Published 2019-06-01
    “…Patients with depression who received care as part of the MHCP had higher rates of response (52.2% in the treatment group vs 26.9% in the comparison/usual care group), early remission (70.2% in the treatment group vs 44.8% in the comparison/usual care group) and recovery (56.1% in the treatment group vs 28.5% in the comparison/usual care group), but there was no impact of treatment on their functioning.Conclusions While dedicated human resources (eg, Case Managers) and dedicated space for mental health clinics (eg, Mann-Kaksha) strengthen the ‘formal’ healthcare platform, without substantial additional investments in staff, such as Community Health Workers/Accredited Social Health Activists to improve community level processes and provision of community-based continuing care to patients, we are unlikely to see major changes in coverage or clinical outcomes.…”
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  14. 1354

    Reassessing Adaptational Lag in Eriophorum vaginatum: Short-Term Responses to Reciprocal Transplant and Passive Warming Experiments in Northern Alaska by Jennifer Lynn Chandler, James B McGraw, Michael L Moody, Jianwu Tang, Janice Voltzow, Ned Fetcher

    Published 2025-08-01
    “…This study’s short duration likely limited our ability to detect differences in tiller population growth as a function of garden or ecotype, emphasizing the need for long-term monitoring.…”
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  15. 1355

    Ecotoxicological evaluation in aquaculture in state park Serra do Mar-SP, Nucleo Itariru by Bruno Galvão de Campos, Denis Moledo de Souza Abessa, Mauro Cornacchioni Lopes, Newton José Rodrigues da Silva

    Published 2014-01-01
    “…However, farming tanks appeared to function as biological filters, due to the occurrence of physical, chemical and biological (microbial degradation) processes, producing non toxic effluents. …”
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  16. 1356

    Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight. by Eli Elyas, Alex Grimwood, Janine T Erler, Simon P Robinson, Thomas R Cox, Daniel Woods, Peter Clowes, Ramona De Luca, Franco Marinozzi, Jérémie Fromageau, Jeffrey C Bamber

    Published 2017-01-01
    “…A needle, embedded in the gel, was excited to vibrate along its long axis and the displacement as a function of time and distance from the needle associated with the resulting shear waves was detected using four M-mode images acquired simultaneously using a commercial four-channel swept-source OCT system. …”
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  17. 1357

    From ancient practices to contemporary green building: Analyzing organic additives in Pitalkhora earthen plasters for sustainable construction by Bhushan Dighe, Manager Rajdeo Singh

    Published 2025-07-01
    “…The findings underscore the resource-efficient approach of early builders in material selection. …”
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    Differential expression of five genes during sclerotium formation of Rhizoctonia solani by WANG Wei, YANG Hui, WANG Zhengyi, CHEN Weiliang

    Published 2013-01-01
    “…Rhizoctonia solani is an important plant pathogenic fungus with a wide host range and worldwide distribution, and the sclerotia are the main source of infection for the diseases caused by this pathogen. …”
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