Risks as an object of internal control: identification and assessment by М.М., I.I.

“…The main purpose of internal control is to ensure timely detection and analysis of business risk, reliability of relevant information, integrity of assets, compliance with regulations, internal policies and procedures, implementation of plans and efficient use of resources. …”
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Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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MergeBot: A platform of semi-structured merge conflict resolution for C/C++ code by Hua He, Xiaofan Liu, Lei Xu, Guanghui Mei, Jifeng Xuan

“…In software version control systems, like Git, merge conflicts typically arise when multiple developers edit the same segment of a source file from different branches. Detecting merge conflicts can be automated; however, resolving merge conflicts is tedious and demanding. …”
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BIOINFORMATICS — INSTRUMENT INTERPRETATION PROTEOMIC PROFILES OF MEAT PROTEIN by N. L. Vostrikova, I. M. Chernukha

“…Studies in this field have enabled formulating and significantly expanding the approaches to the identification and quantification of protein markers of quality, functionality and safety of meat raw material (detection of falsification) in the finished meat products. …”
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Kajian Farmakoinformatika Senyawa Alkaloid Anggur Laut (Caulerpa racemose) Sebagai Inhibitor Collagenase Dalam Mekanisme Antiaging by Dewi Ratih Tirto Sari, M.Eko Pranoto, Siti Zamilatul Azkiyah

“…Sea grapes also well known as functional food source from marine, contains high protein, fibers and secondari metabolites. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t... by Mário Henrique Girão Faria, Régia Maria do Socorro Vidal do Patrocínio, Manoel Odorico de Moraes Filho, Silvia Helena Barem Rabenhorst

“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake by Leah R. N. Samuels, Houston C. Chandler, Michelle Hoffman, John A. Kronenberger, Michele Elmore, Robert Aldredge, Benjamin S. Stegenga, James E. Bogan Jr., Mark A. Davis, Stephanie Hertz, Michael K. Schwartz, Taylor Wilcox

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Conditions for the emergence of circumnutations in plant roots. by Ilya Loshchilov, Emanuela Del Dottore, Barbara Mazzolai, Dario Floreano

“…Here we describe a model capable of replicating root growth behaviors, which we used to analyze the role of circumnuntations, revealing their emergence I) under gravitropic stress, as a combination of signal propagation and sensitivity to the signal carriers; II) as a result of the interplay between gravitropic and thigmotropic responses; and III) as a behavioral strategy to detect and react to resource gradients. The latter function requires the presence of a hypothetical internal oscillator whose parameters are regulated by the perception of environmental resources.…”
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Chromosome-level genome assembly of starry flounder (Platichthys stellatus) by Weiwei Zheng, Changlin Liu, Shenglei Han, Tengteng Wang, Tao Yang, Zhihong Liu, Dong Xu, Huizong Han, Xiaoqing Xi, Changwei Shao, Kaiqiang Liu

“…Approximately 94.02% of assembled sequences were anchored into 24 pseudochromosomes, and a total of 18 telomeres were detected. Totally 22,835 protein-coding genes and 227.87 Mb repetitive sequences were identified. …”
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Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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In-band network telemetry system based on high-performance packet processing architecture VPP by Tian PAN, Xingchen LIN, Jiao ZHANG, Tao HUANG, Yunjie LIU

“…An in-band network telemetry-based system was built based on VPP, a high-performance virtual network forwarding architecture/device, via reorganizing the data plane pipeline processing modules.Moreover, a network-wide telemetry mechanism was further developed via embedding source routing into the probe packet header for specifying the route of probe packets.Finally, a virtual network topology was built with performance evaluation conducted.The evaluation shows that the telemetry system can monitor the network in a high precision of every 0.13 ms, detecting link congestion in real time with minor performance overhead.Given virtual network devices have been widely deployed in data centers, the proposed scheme is expected to improve the reliability of multi-tenancy and network function virtualization in data centers via high-precision, network-wide virtual link telemetry coverage.…”
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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals by Edanur Güler–Ekmen, İsmail Çağrı Yılmaz, Talat Güler, Derya Güler, Mehtap Özçelik

“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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MULTI-MODEL STACK ENSEMBLE DEEP LEARNING APPROACH FOR MULTI-DISEASE PREDICTION IN HEALTHCARE APPLICATION by Bhaskar Adepu, T. Archana

“…These datasets serve two functions: improving illness prediction and examining large data reservoirs to identify previously unknown disease patterns. …”
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Substandard Language Phenomena in Artistic Discourse by Anzhelika V. Korolkova, Tatyana S. Novikova

“…The substandard is currently becoming a source of replenishment of the stylistically reduced layer of modern colloquial speech.…”
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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. by Michele Vacca, Simona D'Amore, Giusi Graziano, Andria D'Orazio, Marica Cariello, Vittoria Massafra, Lorena Salvatore, Nicola Martelli, Stefania Murzilli, Giuseppe Lo Sasso, Renato Mariani-Costantini, Antonio Moschetta

“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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