Landscape of extracellular small RNA and identification of biomarkers in multiple human cancers by Shoubin Zhan, Ye Xu, Botao Li, Peng Ge, Chunwu Zhang, Shengkai Zhou, Tingting Yang, Gaoli Liang, Ling Ji, Xiangbin Kong, Ping Yang, Xi Chen, Chen-Yu Zhang, Han Shen, Xu Luo, Zhen Zhou, Yanbo Wang

“…Summary: Extracellular RNAs (exRNAs) in biofluids, sourced from diverse tissues, exhibit various biological functions and diagnostic potential. …”
Get full text

Phosphate transporter gene families in rye (Secale cereale L.) – genome-wide identification, characterization and sequence diversity assessment via DArTreseq by David Chan-Rodriguez, Brian Wakimwayi Koboyi, Sirine Werghi, Bradley J. Till, Julia Maksymiuk, Fatemeh Shoormij, Abuya Hilderlith, Anna Hawliczek, Maksymilian Królik, Hanna Bolibok-Brągoszewska

“…Each PHT family has a particular physiological and cellular function. Rye (Secale cereale L.) is a member of Triticeae, and an important source of variation for wheat breeding. …”
Get full text

eDNA Metabarcoding Reveals the Depth-Structured Variation of Coral Reef Fish by Jinfa Zhao, Lin Lin, Yong Liu, Teng Wang, Yu Liu, Yayuan Xiao, Jianzhong Shen, Hongyu Xie, Hai Huang, Qiuying Han

Get full text

An Interdisciplinary Ecosystem for the Prevention of Cardiotoxicity in Older Patients With Breast Cancer: Protocol for a Prospective and Multicentric Study by Gaia Giulia Angela Sacco, Ketti Mazzocco, Anastasia Constantinidou, Andri Papakonstantinou, Davide Mauri, Grigorios Kalliatakis, Manolis Tsiknakis, Domen Ribnikar, Dorothea Tsekoura, Valantis Aidarinis, Kalliopi Keramida, Panagiotis Oikonomopoulos, Athos Antoniades, Cameron Brown, Federica Rizzi, Anca Bucur, Elsa Pacella, Georgia Karanasiou, Daniela Cardinale, Carlo Cipolla, Elisabetta Munzone, Dimitrios Fotiadis, Giuseppe Curigliano, Gabriella Pravettoni

“…In total, 750 older patients with breast cancer (aged ≥60 years) are assigned to either the standard practice or enhanced monitoring group, with only patients in the latter receiving access to eHealth psychological, behavioral, and functional interventions implemented on the CARDIOCARE eHealtHeart app. …”
Get full text

Reconstruction of U.S. Regional-Scale Soybean SIF Based on MODIS Data and BP Neural Network by YAO Jianen, LIU Haiqiu, YANG Man, FENG Jinying, CHEN Xiu, ZHANG Peipei

“…Through the activation functions in the BP neural network, it enhanced the understanding of the complex nonlinear relationships between the original SIF data and these MODIS products. …”
Get full text

Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
Get full text

Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
Get full text

Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
Get full text

3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
Get full text

Trend analysis of the application of multispectral technology in plant yield prediction: a bibliometric visualization analysis (2003–2024) by Jiahui Xu, Jiahui Xu, Jiahui Xu, Yalong Song, Yalong Song, Yalong Song, ZhaoYu Rui, ZhaoYu Rui, Zhao Zhang, Zhao Zhang, Can Hu, Can Hu, Can Hu, Long Wang, Long Wang, Long Wang, Wentao Li, Wentao Li, Wentao Li, Jianfei Xing, Jianfei Xing, Jianfei Xing, Xufeng Wang, Xufeng Wang, Xufeng Wang

“…Over the past decade, multispectral image acquisition and information extraction from plants have provided rich data resources for scientific research, facilitating a deeper understanding of plant growth mechanisms and ecosystem function. …”
Get full text

Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad... by Fernanda Ginani, Diego Moura Soares, Carlos Augusto Galvão Barboza

“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
Get full text

Effect of the diet level of whole-plant corn silage on the colonic microflora of Hezuo pigs by Qiaoli Yang, Longlong Wang, Pengfei Wang, Zunqiang Yan, Qiong Chen, Pengxia Zhang, Jie Li, Rui Jia, Yao Li, Xitong Yin, Shuangbao Gun

“…Background Whole-plant corn silage (WPCS) is an important roughage source for livestock, and have critical influences on rumen or intestinal microbiota, thus affecting the growth performance and feed efficiency. …”
Get full text

Assessment and Optimization of Hydrological Connectivity for Effective Management of Water Resources in the Samian Watershed by Zeinab Hazbavi, Nazila Alaei

“…Accordingly, increasing attention has been given to the structural and functional connectivity of river networks as the primary source of surface water supply, while this can be a potential watershed-scale management solution. …”
Get full text

Research on Pedestrians’ Visual Perception Characteristics Based on USGGS: A Case Study of the Six Inner-City Districts of Tianjin by Hanwen YANG, Shang’en TSOU, Yike HU

“…The core objective of the research is to propose strategies to optimize the greening structure of urban streets by analyzing the correlation between USGGS and visual perception of pedestrians, so as to enhance the quality of the visual environment of street pedestrians, improve the urban human settlement environment and promote the organic integration of the urban ecological and humanistic environments, thus providing a new way of thinking for urban planning and construction, and promoting the high-quality and sustainable development of urban street space.MethodsThe research selects the six inner-city districts of Tianjin City as the research area, utilizes Baidu street view image (SVI) as data source, and collect SVIs and their coordinates in the six districts in 2019 by calling Baidu API, with a total of 17,326 points selected and 13,281 valid samples obtained after screening. …”
Get full text

Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review by Dikshyanta Rana, Sophie Westrop, Nishant Jaiswal, Evi Germeni, Arlene McGarty, Louisa Ells, Phillippa Lally, Michael McEwan, Craig Melville, Leanne Harris, Olivia Wu

“…To synthesise the data, the richest sources were identified through rereading the studies. …”
Get full text

Cinnamaldehyde supplementation in sows and their offspring: effects on colostrum and milk composition, performance, redox status and intestinal health by Junqi Jin, Shiya Liu, Qiang Zhou, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, Hefeng Luo, Xiuming Liu, De Wu, Lianqiang Che

“…Moreover, maternal CA supplementation or post-weaning CA supplementation improved nutrient digestibility, redox status, and intestinal function-related parameters of weaned piglets.…”
Get full text

Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…First, in order to form the theoretical foundations of the research, an comprehensive search was conducted among articles, books, researches, reports and other reliable scientific sources. Then, the topic in question was examined in relation to the selected countries (based on the 2022 Global Innovation Index report) in order to provide a basis for a comparative study and comparison of Iran's situation with the mentioned countries. …”
Get full text

Candidate gene identification and marker development for seed coat peeling rate in peanut (Arachis Hypogaea L.) by Hongfei Liu, Ziqi Sun, Feiyan Qi, Xiao Wang, Meng Zhang, Juan Wang, Xiaobo Wang, Ziqiang Mo, Mingbo Zhao, Chenyang Zhi, Mengmeng Wang, Zhiyuan Zhou, Linhong Xu, Wenzhao Dong, Zheng Zheng, Xinyou Zhang

“…Furthermore, a functional marker A05.114993389 was developed and validated in both the natural and RIL populations, providing a valuable genomic resource for marker-assisted selection (MAS) in peanut breeding programs. …”
Get full text

A Jurisprudential and Legal Inquiry into the Foundations and Limits of the Liability of Manufacturers of Internet of Things Devices by Zahra Sadat Mirhashemi, Fatemeh Najib Zadeh, Moein Gholamalipour

“…Manufacturers, as the primary creators and suppliers, hold a unique status in ensuring the proper functioning of these products. In contexts like Iran, where suitable legislative frameworks are lacking, it becomes imperative to explore the foundational jurisprudential and legal principles that could guide the establishment of manufacturer liability within the Islamic legal system…”
Get full text

Glucocorticoids and antivirals for HBV reactivation in onco-hematologic patients by Michela di Fonzo, Andrea Marengo, Alfredo Marzano, Antonella Ferrari, Bruno Monarca, Gianfranco delle Fave, Massimo Marignani

“…In this later autopsy detected cirrhosis, not evident at presentation. This clinical experience suggests that in patients with &lt;span&gt;onco-hematological&lt;/span&gt; and persistent liver function tests alterations in spite of effective antiviral response, glucocorticoids could control the effects of immune response. …”
Get full text