Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility by Jiao Gong, Huiru Sun, Kaiyuan Wang, Yanhui Zhao, Yechao Huang, Qinsheng Chen, Hui Qiao, Yang Gao, Jialin Zhao, Yunchao Ling, Ruifang Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Sijia Wang, Jiucun Wang, Guoqing Zhang, Shuhua Xu, Feng Qian, Fang Zhou, Huiru Tang, Dali Li, Chinese Pangenome Consortium (CPC), Fritz J. Sedlazeck, Li Jin, Yuting Guan, Shaohua Fan

“…Abstract Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. …”
Get full text

Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
Get full text

Evaluating Factors Affecting Interior Architectural Space Quality to Enhance Spatial Resilience and Human Productivity: An Application of Maslow’s Hierarchy of Needs by Moharam Ghahremani Drvish, Farhang Mozafar, Ceyed bagher Hoseini, Fateme Mahdizadeye seraj

“…On the contrary, in our proposed model, the development of biological and psychological factors that are in accordance with the functional needs is the cause of ensuring the quality of the space, and the response to the mentioned needs through the realization of the quality components of the space, fulfills the resilience in the space. …”
Get full text

Integrated care programmes for sport and work participation, performance of physical activities and quality of life among orthopaedic surgery patients: a systematic review with met... by Maurits W van Tulder, Pieter Coenen, Gino M Kerkhoffs, Gerben Hulsegge, Joost G Daams, Rutger C van Geenen, Judith A Huirne, Johannes R Anema, P Paul Kuijer

“…We aimed to assess the effectiveness of integrated care among orthopaedic surgery patients.Design Systematic review with meta-analysis.Data source Medline, EMBASE and CINAHL (until 17 June 2019).Eligibility for selecting studies We searched for controlled studies on integrated care interventions consisting of active referral to case managers, rehabilitation with participation-based goals and/or e/mHealth, with outcomes of sports and work participation, performance of physical activities and/or QoL. …”
Get full text

Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. …”
Get full text

Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response by Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe

“…Across bvFTD and PSP groups, the beta response to deviant stimuli (relative to standard stimuli) correlated with clinical severity, but not with atrophy of the prefrontal source region. These findings confirm the proposed importance of higher-order cortical regions, and their beta-power generators, in sensory change detection and context-updating during oddball paradigms. …”
Get full text

Exploring causal relationships between brain imaging-derived phenotypes and ovarian cancer risk: a bidirectional Mendelian randomization by Ting Liu, Xiaoqian Tuo, Huifang Zhao, Yan Wang, Yu Jiang, Jiaojiao Lu

“…We selected single nucleotide polymorphisms (SNPs) as instrumental variables based on rigorous criteria. …”
Get full text

Price transmission and market integration analysis of black gram (urad dal) across major Indian states by Sukhvir Singh, Amit Guleria, Parvender Sheoran, Pankaj Sood, Vishal Mahajan, Dharminder Kumar, Satbir Singh, Gurdeep Singh, Rajesh K. Rana

“…BackgroundBlack gram (Vigna mungo), a key pulse crop in India, serves as a major protein source with significant health benefits. Predominantly grown in Madhya Pradesh, Uttar Pradesh, and Rajasthan, its cultivation in Punjab remains limited due to the paddy-wheat dominance. …”
Get full text

Meta Analysis of Clustering Nursing for Stroke Associated Pneumonia by Chunyan HAN, Cun ZHAO, Xinglei WANG, Yali CHANG, Li YAO, Yihong KE, Jinhui TIAN, Xinman DOU

“…If the homogeneity between the studies was good (<italic>P</italic>≥0.1, <italic>I</italic>²≤50%), select the fixed effect model, if there was heterogeneity between these studies (<italic>P</italic>&lt;0.1, <italic>I</italic>²&gt;50%), analyze the source of heterogeneity, and if there was no clinical heterogeneity, choose a random effects model.Results:A total of 11 clinical randomized controlled trial literatures were finally included. …”
Get full text

Health-Related Messages About Herbs, Spices, and Other Botanicals Appearing in Print Issues and Websites of Legacy Media: Content Analysis and Evaluation by Ann Gaba, Richard Bennett

“…Therefore, legacy media may be considered a credible source of information to readers about these topics.…”
Get full text

Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China by Hui Jin, Hui Jin, Cong Wang, Cong Wang, Yi-Yue Yang, Yi-Yue Yang, Lie Zhou, Lie Zhou, Yun Xiao, Yun Xiao, Yang Wen, Yang Wen, Jawad Ahmad, Jawad Ahmad, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Ming Li, Wei Luo, Xiao-Fei Zhou, Jian-Jun Luo, Bo Liu, Eric Yu-Hai Chen, Mao-Sheng Ran, Mao-Sheng Ran

“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
Get full text

Pathogenicity and virulence of Aeromonas schubertii in farmed Asian seabass (Lates calcarifer) in Thailand by Clara Trullàs, Sirikorn Kitiyodom, Komkiew Pinpimai, Putita Chokmangmeepisarn, Manoj Tukaram Kamble, Channarong Rodkhum, Nopadon Pirarat

Get full text

Investigation of high fecundity genes by nanopore sequencing in sheep (Ovis aries) pituitary by Xue Xiao, Zhibin Ji, Tong Wang, Dejie Zhu, Zhonghui Li, Xinming Xu, Fen Li

Get full text

Unraveling the mitochondrial genome of the medicinal Chinese motherwort (Leonurus japonicus, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary i... by Xinyu Bai, Xinyu Bai, Tingting Zhu, Huiru Chen, Xiaoqun Wang, Jing Liu, Yuqing Feng, Yuqing Feng, Yanbo Huang, Joongku Lee, Goro Kokubugata, Zhechen Qi, Xiaoling Yan

“…Extensive RNA editing underscores post-transcriptional regulation in mitochondrial function. These findings enrich genomic resources for Leonurus, support phylogenetic and evolutionary studies in Lamiaceae, and lay groundwork for molecular breeding and conservation strategies targeting mitochondrial traits. …”
Get full text

Determination of Trace Elements in Corydalis conspersa and Corydalis linarioides by ICP-AES by Qing Du, Yanguo Cai, Zhi Chen, Dongliang Wei, Yande Cao, Ying Chen, Shulin Yu, Qianqian Zhao, Jiang Wu, Mingdi Liu

Get full text

A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors by Shuai Zhao, Shuai Zhao, Shuai Zhao, Lin Cheng, Xingzhao Ji, Xingzhao Ji, Shengnan Sun, Shengnan Sun, Shengnan Sun, Yi Liu, Yi Liu, Qiang Wan, Qiang Wan, Qiang Wan

“…We also used the Tumor Immune Estimation Resource 2.0 (TIMER 2.0) database to investigate the association between ZNF514 expression and immune checkpoint genes and immune infiltration. …”
Get full text

Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…One-third of the included studies used the leaves of the selected plants. The reviewed studies highlighted neuroprotective activities of the plants, as evidenced by biochemical and behavioral improvements. …”
Get full text

Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review by Ukachukwu O Abaraogu, Philippa Dall, Chris Seenan, Sarah Rhodes, Trish Gorely, Joanna McParland, Julie Brittenden, Ebuka M Anieto, Lorna Booth, Cathy Gormal, Jeremy Dearling, Candida Fenton, Sarah Audsley, Kimberley Fairer, Lindsay Bearne, Dawn A Skelton

“…Conclusions The behaviour change technique-based interventions are effective, targeting intention to engage in physical activity, in improving daily physical activity and functional outcomes in the short term, although evidence is limited for maintenance. …”
Get full text

Design of a monitoring program to advance nightjar conservation along the Atlantic Flyway by Marie I. Tosa, Anthony J. Roberts, Amy K. Tegeler, Patrick K. Devers, Logan A. M. Parker, Pamela D. Hunt, Bryan D. Watts, Min Huang, Andrew C. Vitz, Sara H. Schweitzer, Samantha Robinson, Matthew D. Palumbo, Ryan Rebozo

Get full text

The Trend of Residential-Livelihood Changes in Nomadic Ecosystems with Environmental Sustainability Approach (Case Study: Farsimadan Tribe Ecosystem, Fars Province) by Siamak Tahmasbi, Seyed Ali Badri, Mohammad Reza Rezvani

“…In this change, a lot of structures and functions of nomadism have changed. In the past, livestock was impartible components of nomadic life having the value and dignity among nomads and well- known people who had more livestock in the tribe. …”
Get full text