Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading by Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng

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High-quality bonds: serine acetyltransferase 2 gene revealed by GWAS is associated with grain protein content in spring durum wheat by Aleksey Ermolaev, Ludmila Bespalova, Varvara Korobkova, Aleksey Yanovsky, Lubov Nazarova, Aleksandra Kroupina, Anastasia Chernook, Aleksandra Mudrova, Viktoria Voronezhskaya, Viktoria Voronezhskaya, Pavel Kroupin, Gennady Karlov, Mikhail Divashuk, Mikhail Divashuk

“…The developed KASP markers demonstrated robust allelic discrimination, offering practical tools for marker-assisted selection. This study provides actionable genetic resources for breeding high-protein spring durum wheat genotypes.…”
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Differential expression of five genes during sclerotium formation of Rhizoctonia solani by WANG Wei, YANG Hui, WANG Zhengyi, CHEN Weiliang

“…Rhizoctonia solani is an important plant pathogenic fungus with a wide host range and worldwide distribution, and the sclerotia are the main source of infection for the diseases caused by this pathogen. …”
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Reactive Oxygen Species in Asthma: Regulators of Macrophage Polarization and Therapeutic Implications: A Narrative Review by Liu Y, Zhang M, Wang T, Zhang J

“…ARG1 rich M2 cells convert L-arginine into proline, fostering collagen deposition; Ym1/2, Fizz1 and CD206 correlate with airway remodeling and declining lung function. Emerging antioxidant and macrophage-polarization strategies that selectively modulate ROS show promise in rebalancing M1/M2 responses and attenuating airway hyper-responsiveness. …”
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Immunogenetic diversity of MHC class II B-Lβ genes in Brazilian Caipiras (free-range) chickens laying blue eggs by Carlos André da Veiga Lima Rosa Costamilan, Ediane Paludo, Marcos Edgar Herkenhoff, Fábio Pértille, André Luigi Soares de Souza, Carolina Rosai Mendes, Guilherme Dilarri, Guilherme Dilarri

“…Conservation and utilization of this genetic resource can contribute to the development of healthier and more disease-resistant commercial chicken lines.…”
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Saline-alkali soil reclamation and utilization in China: progress and prospects by Guangzhou WANG, Gang NI, Gu FENG, Haley M. BURRILL, Jianfang LI, Junling ZHANG, Fusuo ZHANG

“…Following the soil management strategies, the concept of selecting crops for saline soil is proposed. This encompasses halophyte planting, salt-tolerant crop breeding and the application of saline-adapted functional microorganisms to improve the adaptation of crops. …”
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Comparative study of nosZI and nosZII clade isolates: insights into their responses to environmental variables and soil fertilization types by Haoran Li, Qishi Luo, Lichao Sun, Huicui Xu, Xiaodong Hao, Kai Zhu, Ming Li, Bao Li, Wei Jiao, Jibiao Geng, Zhiqun Chen, Lihua Huang, Zongwei Xia

“…In contrast, the nosZI strain tended to increase emissions, except under the mixed fertilization regime.DiscussionThese findings highlight the importance of selecting N2O-reducing microbial strains based on their functional capacity and environmental tolerance. …”
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Obstacle shape determination by mobile robot sensor system using GP2Y0A (Sharp) type IR distance sensors by V. P. Andreev

“…However, such a sensor can only detect an obstacle and determine а distance to a certain point on its surface. …”
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Identification of Cancer Stem Cell (CSC)-Associated Genes, Prognostic Value, and Candidate Drugs as Modulators of CSC-Associated Signaling in Carcinomas Through a Multiomics Data A... by Pallabi Mondal, Poulami Singh, Krishna Mahanti, Sankar Bhattacharyya

“…This ability of CSCs to escape immune responses makes the CSCs a primary source of functionally altered, immune-resistant, chemoresistant, aggressive tumor cells. …”
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Reduction of Total Phenols in Virgin Olive Oil as a Preservation Medium during Cold Storage of Whey Cheese and Tofu by Valerija Majetić Germek, Ivana Gobin, Doris Franjković, Marija Marković, Olivera Koprivnjak

“…Virgin olive oil, known as a good source of health-promoting hydrophilic phenols, is traditionally used as a medium for preserving various foods. …”
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Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation by Jialiang S. Wang, Katelyn Strauss, Caroline Houghton, Numa Islam, Sung-Hee Yoon, Tatsuya Kobayashi, Daniel J. Brooks, Mary L. Bouxsein, Yingshe Zhao, Cristal S. Yee, Tamara N. Alliston, Marc N. Wein

“…Remarkably, these defects in osteocyte function contrast to only mild changes in mature osteoblast function, suggesting that this Sp7 mutation selectively interferes with the function of Sp7 in osteocytes and mature osteoblasts, but not during early stages of osteoblast differentiation. …”
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Genetic Basis and Exploration of Major Expressed QTL <i>qLA2-3</i> Underlying Leaf Angle in Maize by Yonghui He, Chenxi Wang, Xueyou Hu, Youle Han, Feng Lu, Huanhuan Liu, Xuecai Zhang, Zhitong Yin

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GePIF4 Increases the Multi-Flower/Capsule-Bearing Traits and Gastrodin Biosynthesis in <i>Gastrodia elata</i> by Yue Xu, Zhiqing Wu, Yugang Gao, Pu Zang, Xinyu Yang, Yan Zhao, Qun Liu

“…It was confirmed that GePIF4 has multiple biological functions in the overexpression of transgenic lines, including increasing numbers of vegetative propagation corms (VPCs) and promoting the growth of <i>G. elata</i>. …”
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Trispecific SEED antibodies engineered for neutrophil-mediated cell killing by Veronica Natale, Gergely Heves, Katharina Stadlbauer, Florian Rüker, Vanessa Siegmund, Lukas Pekar, Stefan Zielonka, Lars Toleikis, Stefan Becker, Gordana Wozniak-Knopp

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Exploring the Complexities of Seafood: From Benefits to Contaminants by Bettina Taylor, Kelvin Fynn Ofori, Ali Parsaeimehr, Gulsun Akdemir Evrendilek, Tahera Attarwala, Gulnihal Ozbay

“…Seafood plays a vital role in human diets worldwide, serving as an important source of high-quality protein, omega-3 fatty acids, and essential vitamins and minerals that promote health and prevent various chronic conditions. …”
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The impact of early massive galaxy formation on the cosmic microwave background by Eda Gjergo, Pavel Kroupa

“…A previously overlooked foreground component is the formation of massive early-type galaxies (ETGs), which can no longer be ignored, particularly in light of JWST's detection of massive, evolved systems at extreme redshifts (z>13). …”
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Predictive Capabilities and Limitations of Stream Interaction Region Observations at Different Solar Longitudes by R. C. Allen, G. C. Ho, L. K. Jian, G. M. Mason, S. K. Vines, D. Lario

“…Through comparing 10 years of SIRs/CIRs observed at L1 and at STEREO, we have investigated the probability of sequentially detecting SIRs/CIRs at two locations as a function of the difference in heliospheric longitude and latitudinal separation between the two spacecraft. …”
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Bacteriological Quality Assessment of Water Sold in Plastic Jerry cans within Katsina Metropolis, Katsina State, Nigeria. by Galadanchi Fatima A., Shamsuddeen Umar, Yusuf Buhari, Abubakar Abdulazeez, Salisu Mansur Dabai

“…It is the most abundant molecule in living cells, essential for the proper functioning of cells. It is one of the cheap vehicles that transport gastro-intestinal diseases. …”
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Unsustainable anthropogenic mortality threatens the long-term viability of lion populations in Mozambique. by João Almeida, Willem D Briers-Louw, Agostinho Jorge, Colleen Begg, Marnus Roodbol, Hans Bauer, Andrew Loveridge, Matthew Wijers, Rob Slotow, Peter Lindsey, Kristoffer Everatt, Holly Rosier, Sean Nazerali, Lizanne Roxburgh, Hugo Pereira, Mercia da Conceicao, Armindo Araman, Osvaldo J Abrao, Alison J Leslie, Franziska Steinbruch, Vincent N Naude, Samantha K Nicholson

“…Our findings suggest that resilience to anthropogenic threats is largely a function of lion population size as well as resource and management capacity. …”
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