Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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The Role of Landscape Metrics and Spatial Processes in Performance Evaluation of GEOMOD (Case Study: Neka River Basin) by Shrif Joorabian Shooshtari, Kamran Shayesteh, Mehdi Gholamalifard, Mahmood Azari, Juan Ignacio López-Moreno

“…Seven landscape metrics were selected for accuracy assessment of model using Fragstats software (McGarigal et al., 2002). …”
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Representation of a Scientific Supervisor in Internet-Memes by N. V. Stepanova, M. S. Sigaeva

“…The sources of the memes were the podcasts “The Struggling Scientists”,  “The Meming Phd”, “High impact PhD memes”. …”
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Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model. by Walter S Mathis, Maria Ferrara, Shadie Burke, Emily Hyun, Fangyong Li, Bin Zhou, John Cahill, Emily R Kline, Matcheri S Keshavan, Vinod H Srihari

“…Marginal-delay, or the portion of overall delay attributable to a specific node, was computed as the number of days between the start dates of contiguous nodes on the PTC. Sources of delay within the network of care were quantified and patient characteristic (sex, age, race, income, insurance, living, education, employment, and function) influences on such delays were analyzed via bivariate and mixed model testing.…”
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NURSING CARE FOR THE COMFORT OF HOSPITALIZED PATIENTS by Pepa Dzhedzheva

“…Material and methods: the present study is based on the search, selection and critical review of scientific articles and other source documents related to the definition of the concept of comfort in healthcare; factors influencing the comfort of hospitalized patients; importance of comfort in the healing process and nursing care for its improvement. …”
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BICYCLE TRAFFIC IN THE CITIES by Elżbieta MACIOSZEK, Irena JURDANA

“…This article presents the characteristics of the bicycle infrastructure and services offered in selected cities in the world and Poland, as well as the issues of bicycle counters as sources of data on bicycle traffic volume, along with an exemplary analysis of this type of data.…”
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Phonological and Sociolinguistic Challenges of Translating Yorùbá Play, and Game Songs to Singable English for Children by Bolanle O. Sogunro

“…Consequently, the translations are “unperformable” as oral texts, thus, failing their aesthetic and functional purpose for children. To investigate the translation problems involved and proffer solutions, this essay analyses five randomly selected Yoruba songs and seven of their available English translations from online sources and an unpublished manuscript, using sociolinguistic translation theory and the analytical framework of Franzon’s song translation choices. …”
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A Hidden Pulse: Uncovering a New Timing Signal in Cygnus X-1 with AstroSat by Sandeep K. Rout, Federico García, Mariano Méndez, Abhay Kumar, Santosh Vadawale, David M. Russell, Pei Jin

“…This dip in coherence, which we detect for the first time in Cygnus X-1 at energies above 3 keV, appears in a state in which the source shows high-amplitude radio variability and significant hard X-ray polarization. …”
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Melatonin: A Novel Indolamine in Oral Health and Disease by V. K. Chava, K. Sirisha

“…Recent studies, by Claustrat et al. (2005), detected few extrapineal sources of melatonin like retina, gastrointestinal tract, and salivary glands. …”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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On the usage of artificial intelligence in leprosy care: A systematic literature review. by Hilson Gomes Vilar de Andrade, Elisson da Silva Rocha, Kayo H de Carvalho Monteiro, Cleber Matos de Morais, Danielle Christine Moura Dos Santos, Dimas Cassimiro Nascimento, Raphael A Dourado, Theo Lynn, Patricia Takako Endo

“…The persistent stigma and social exclusion associated with leprosy complicate eradication efforts exacerbate the wider challenges faced by NTDs in sourcing the necessary resources and attention for control and elimination. …”
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Identification method of roof rock interface based on response characteristics of drilling parameters by LI Dianshang, LIU Cancan, WANG Chuanbing, REN Bo, REN Shuai, KANG Zhipeng

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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han

“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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PROBABILISTIC SEISMIC HAZARD ANALYSIS IN NORTHERN SUMATERA by Muhammad Aji Permana

“…This method consists of source identification, source characterization, attenuation function selection, and seismic hazard counting. …”
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Enhanced propionate and butyrate metabolism in cecal microbiota contributes to cold-stress adaptation in sheep by Xindong Cheng, Yanping Liang, Kaixi Ji, Mengyu Feng, Xia Du, Dan Jiao, Xiukun Wu, Chongyue Zhong, Haitao Cong, Guo Yang

“…By contrast, Hulunbuir sheep exhibit changes in microbial diversity and function, leading to increased propionate and butyrate metabolism. …”
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ClimKern v1.2: a new Python package and kernel repository for calculating radiative feedbacks by T. P. Janoski, T. P. Janoski, T. P. Janoski, T. P. Janoski, T. P. Janoski, I. Mitevski, R. J. Kramer, M. Previdi, L. M. Polvani, L. M. Polvani, L. M. Polvani

“…<p>Climate feedbacks are a significant source of uncertainty in future climate projections and need to be quantified accurately and robustly. …”
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Reprogrammed Cell‐based Therapy for Liver Disease: From Lab to Clinic by Amir Mehdizadeh, Masoud Darabi

“…The generation of human functional hepatocytes in high quantities for liver cell therapy is an important goal for ongoing therapies in regenerative medicine. …”
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Epidemic preparedness and response capacity against infectious disease outbreaks in 186 countries, 2018–2022 by Paul Eze, Judith Chidumebi Idemili, Friday Onwubiko Nwoko, Nigel James, Lucky Osaheni Lawani

“…From the 2022 submissions, 116 (62%) countries reported functional (Level 4 or 5) prevention capacity, 162 (87%) had functional detection capacity, 118 (63%) had functional response capacity, 121 (65%) had functional enabling resources and coordination capacity, and 133 (72%) had functional operational readiness against public health events. …”
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Unified Weak Lensing Constraints on the Evolution of the Mass–X-Ray Luminosity Relation for Galaxy Clusters by I. Pederneiras, A. Finoguenov, E. Cypriano, J. Comparat, K. Kiiveri, L. van Waerbeke, R. Dupke

“…We also analyzed the impact of the selection function on calibration, finding that its full modeling is essential.…”
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Study of Complex Impedance Dispersion Model for Two-Phase Laminar Flow by CHENG Linfeng, KE Shizhen, SHI Hongwei, ZHANG Yuhang, LUO Hu, TAO Jie

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