A novel acidic laminarinase derived from Jermuk hot spring metagenome by Ani Paloyan, Tigran Soghomonyan, Mariam Karapetyan, Hasmik Grigoryan, Anna Krüger, Fiona Cuskin, Jon Marles-Wright, Christin Burkhardt, Garabed Antranikian

“…Abstract Laminarinase, an enzyme with a specific affinity for laminarin—a complex polysaccharide found in the cell walls of brown algae and select marine organisms—was investigated in this study. …”
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Machine learning prediction of pKa of organic acids by Juda Baikété, Alhadji Malloum, Jeanet Conradie

“…Further molecular descriptors have been generated using density functional theory (DFT) calculations, and RDKit library. …”
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Environmental impact assessment of maize cultivation system considering different irrigation methods by Filippo Vigo, Michele Zoli, Daniela Lovarelli, Jacopo Bacenetti

“…One ton of ear maize silage at 48% moisture content was selected as functional unit and a “from cradle to farm gate” was considered as system boundary . …”
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Exploring interactions between shading and view using visual difference prediction by Stephen Wasilewski, Marilyne Andersen

“…This paper is an exploration of how to approach the characterisation of view clarity through different facades as a function of both the facade and the view itself. While the findings are preliminary, there is already an indication that the type of view content matters to how well people will see through different systems, an important consideration when planning mock-ups and selecting shade fabrics, blinds or electrochromic glazing.…”
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Identification and molecular docking mechanism of novel anti-inflammatory peptides from Lactobacillus paraplantarum fermented Cannabis sativa L. (hemp) seeds by Lingyue Shan, Akanksha Tyagi, Hun Ju Ham, Deog Hwan Oh

“…Overall, these findings indicate that hemp seeds have potential to be a source of bioactive peptides for functional foods with anti-inflammatory properties.…”
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Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma by Yanfang Huang, Guoxian Luo, Xiujie Sheng, Jianqi Li

“…Cuproptosis-related genes were sourced from previously published studies and the FerrDb database. …”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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GWAS and WGCNA analysis uncover candidate genes associated with drought in Brassica juncea L. by Yusong Zhang, Yusong Zhang, Xiaoyan Yuan, Xiaoyan Yuan, Yunyun Zhang, Yunyun Zhang, Yanqing Luo, Yanqing Luo, Kaiqin Zhao, Kaiqin Zhao, Feng Zu, Feng Zu, Zhengshu Tian, Zhengshu Tian, Jinfeng Li, Jinfeng Li, Lifan Zhang, Lifan Zhang, Xiaoying He, Xiaoying He, Jinxiang Gao, Jinxiang Gao, Minglian Fu, Minglian Fu, Genze Li, Genze Li, Feihu Liu

“…To screen drought-tolerant germplasm resources and key functional genes related to drought tolerance in Brassica juncea L.(193 accessions), three treatments were applied at the germination and seedling stages:control(CK), moderate drought stress (M), and severe drought stress (S). …”
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A Comprehensive Study on the Nutritional Profile and Shelf Life of a Custom-Formulated Protein Bar Versus a Market-Standard Product by Corina Duda-Seiman, Liliana Mititelu-Tartau, Simona Biriescu, Alexandra-Loredana Almășan, Bianca-Oana Bitu, Adina-Ioana Bucur, Andrei Luca, Bogdan Hoinoiu, Teodora Hoinoiu

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Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation by Hongyan Xu, Hongyan Xu, Guocai Han, Yanyan Li, Qing Meng, Qing Meng, Yang Zhang, Yayi Wang, Songling Li

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Barriers to and facilitators of rehabilitation according to socio-economic status, after acute respiratory distress syndrome due to COVID-19: A qualitative study in the RECOVIDS co... by Mathilde Kléber, Nicolas Meunier-Beillard, Isabelle Fournel, Eléa Ksiazek, Marine Jacquier, Fiona Ecarnot, Jean-Philippe Rigaud, Pierre-Louis Declerq, Jean-Pierre Quenot, Marie Labruyère

“…<h4>Background</h4>The COVID-19 pandemic may have compounded social disparities in access to healthcare, with possible deleterious consequences on the functional prognosis of patients after a stay in the intensive care unit (ICU). …”
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Mortalin overexpression predicts poor prognosis in early stage of non–small cell lung cancer by Jie Sun, Shuan-Long Che, Jun-Jie Piao, Ming Xu, Li-Yan Chen, Zhen-Hua Lin

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Fate and risks of potentially toxic elements associated with lacustrine groundwater discharge: quantification, modeling, and biogeochemistry by Shen Qu, Juliang Wang, Keyi Zhang, Mengyu Fan, Yuanzhen Zhao, Xu Yang, Zhongli Wang, Helena I. Gomes, Rachel L. Gomes, Limin Duan, Shaogang Dong, Ruihong Yu

“…Thus, self-organizing maps (SOM) and positive matrix factorization (PMF) were employed in present work to decipher source of selected PTE (Li, V, Mn, Cr, Co, Ni, Cu, Zn, Ba, Pb, U, Sr) in Ulansuhai Lake basin (Inner Mongolia, China). …”
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Comparative study of nosZI and nosZII clade isolates: insights into their responses to environmental variables and soil fertilization types by Haoran Li, Qishi Luo, Lichao Sun, Huicui Xu, Xiaodong Hao, Kai Zhu, Ming Li, Bao Li, Wei Jiao, Jibiao Geng, Zhiqun Chen, Lihua Huang, Zongwei Xia

“…In contrast, the nosZI strain tended to increase emissions, except under the mixed fertilization regime.DiscussionThese findings highlight the importance of selecting N2O-reducing microbial strains based on their functional capacity and environmental tolerance. …”
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Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…Nevertheless, methods based on additional information sources (like further sensors or meteorological data) are also discussed. …”
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Personality and Personality Disorders in Medication-Overuse Headache: A Controlled Study by SWAP-200 by Federica Galli, Annalisa Tanzilli, Alessandra Simonelli, Cristina Tassorelli, Grazia Sances, Micol Parolin, Patrizia Cristofalo, Ivan Gualco, Vittorio Lingiardi

“…At levels of specific PDs, MOH patients showed higher obsessive and dysphoric traits and better overall psychological functioning than SUD and PD patients. Conclusion. Although MOH, SUD, and PD populations have been evaluated in multiple sites with different levels of expertise, the study supported the presence of a specific constellation of personality in MOH patients including obsessive (perfectionist) and dysphoric characteristics, as well as good enough psychological resources. …”
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Phosphate transporter gene families in rye (Secale cereale L.) – genome-wide identification, characterization and sequence diversity assessment via DArTreseq by David Chan-Rodriguez, Brian Wakimwayi Koboyi, Sirine Werghi, Bradley J. Till, Julia Maksymiuk, Fatemeh Shoormij, Abuya Hilderlith, Anna Hawliczek, Maksymilian Królik, Hanna Bolibok-Brągoszewska

“…Each PHT family has a particular physiological and cellular function. Rye (Secale cereale L.) is a member of Triticeae, and an important source of variation for wheat breeding. …”
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Prevalence and contributing factors of depression among women with infertility in low-resource settings: a systematic review and meta-analysis by Shimelis Tadesse, Henok Kumsa, Gemeda Wakgari Kitil, Alex Ayenew Chereka, Getnet Gedefaw, Fiker Chane, Esuyawkal Mislu

“…Subgroup and sensitivity analyses were performed to identify the potential source/s of heterogeneity. A p-value of 0.05 was declared as statistically significant. …”
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Accumulation of long-chain unsaturated fatty acids in the airway inflammatory microenvironment drives eosinophil etosis and corticosteroid resistance by Yurong Bai, Pengda Fang, Shasha Li, Zhenhao Xiao, Wenyi Chen, Wenlong Li, Xinyue Wang, Jingyuan Chen, Yue Li, Junhai Chen, Weiqiang Huang, Xin Luo, Shigeharu Ueki, Deyu Fang, Qintai Yang, Yana Zhang

“…Functional analyses were performed on purified eosinophils. …”
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes by Praveen Patel, Rory Collins, Richard Peto, Mark Davies, Sanjiv Banerjee, David Simpson, John Anderson, Louise Bowman, Peter Scanlon, Amanda Adler, Andrew Farmer, Helen Cook, Laura Evans, Elizabeth Williamson, Louis Bolter, Jane Armitage, Peter Sandercock, Richard Gray, Nilesh Samani, Tasso Gazis, Richard Haynes, Arun Sachdev, Eric Wu, Elizabeth Wincott, Peter Sleight, Colin Baigent, Marion Mafham, Sarah Parish, Gavin Brown, Susan Hurley, Lynne Allsop, William Stevens, Theingi Aung, Allen Young, Emily Sammons, Georgina Buck, Imen Hammami, Jill Barton, Jonathan Bodansky, Roger McPherson, Lucy Fletcher, Murphy Kevin, Ryonfa Lee, Sandra Pickworth, Monica Willett, Michael Lay, Ola Murawska, Karen Melham, Jonathan Latham-Mollart, Anna Brewer, Mike Olson, Jude Kay, Alisha Griffiths, Helen Clayton, Philip Kirby, Mike Pennington, Dominic Clarke, Jenny Anslow, Alex Hallam, Jenny Witts, Sarah Egan, Alex Wharton, Amy Derbyshire, Katherine Hepplestone, Sujit Mithra, Su Oliver, Pauline Wiatrak-Olszewska, Kelly Alvey, Nick Gregory, Priyai Parkinson, Prema Maharajan, Rachel McFee, Donna Sowter, John Featonby, Richard Furnival, Helen Lipinski, Hazel Benjamin, Tanisha McAfee, Emma Payne Payne, Liz Still

“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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