A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity. by Andrew P Holmes, Ting Y Yu, Samantha Tull, Fahima Syeda, Stefan M Kuhlmann, Sian-Marie O'Brien, Pushpa Patel, Keith L Brain, Davor Pavlovic, Nigel A Brown, Larissa Fabritz, Paulus Kirchhof

“…<h4>Methods</h4>We used high-resolution optical mapping and sharp microelectrode recordings to quantify regional differences in electrical activation and repolarisation within the intact, superfused murine left atrium and quantified regional ion channel mRNA expression by Taqman Low Density Array. We also performed selected cellular electrophysiology experiments to validate regional differences in ion channel function.…”
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Microplastics as an Emerging Potential Threat: Toxicity, Life Cycle Assessment, and Management by Sameh S. Ali, Mohammed Hussein M. Alsharbaty, Rania Al-Tohamy, Maha A. Khalil, Michael Schagerl, Majid Al-Zahrani, Jianzhong Sun

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Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry by Safaa Salah El-Din Taha, Osama Abd El-Hamid Ibrahim, Einas Hamed El-Shatoury, Amany Mohamed El-Deeb, Hayam Abd El-Naby Sayed

“…A peak β-galactosidase activity of 5.523 U/ ml was recorded at a pH 7, a lactose concentration of 4.6 %, UF-cheese permeate serving as a carbon source, 2 % potassium nitrate (KNO₃) as a nitrogen source, an inoculum size of 5%, and incubated at 37 ºC for 24 h. …”
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Camellia sinensis phytochemical profiling, drug-likeness, and antibacterial activity against gram-positive and gram-negative bacteria: in vitro and in silico insights by Farouk Boudou, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, David Cornu, Mikhael Bechelany, Mikhael Bechelany, Ahmed Barhoum, Ahmed Barhoum

“…Drug-likeness modeling indicated favorable profiles for most compounds, although EGCG violated Lipinski’s rule due to its molecular weight (458.4 g/mol). Density Functional Theory analysis revealed significant variations in electronic properties among the selected compounds, with quercetin exhibiting the smallest HOMO-LUMO gap (2.31 eV), suggesting high reactivity. …”
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Peculiarities of the morphology of the fish stomach by T. Kot, O. Pysanko

“…Histochemical characteristics of the stomach of fish can serve as a theoretical basis for the development of a normal stomach test system for detecting functional changes under the influence of environmental factors.…”
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Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Long-term dynamics of forage base and food supply for nekton in the upper epipelagic layer of the western Bering Sea. Part 2. Food supply for nekton by S. V. Naydenko, A. A. Somov

“…Weak correlation was detected both between the salmon feeding and abundance of their prey and between the salmon feeding and abundance of salmons. …”
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Influence of Solvent Concentration on the Amount of Individual Phenolic Compounds in Apple and Sour Cherry Pomace by Maria Bianca Mandache, Ana-Maria Stoenescu, Sina Cosmulescu

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Biochemical, nutritional, and nutraceutical properties of cactus pear accessions by Yazgan Tunç, Mehmet Yaman, Kadir Uğurtan Yılmaz, Ali Khadivi, Daya Shankar Mishra

“…These findings contribute valuable insights for the conservation and utilization of wild cactus pear genetic resources, supporting the development of functional food products and sustainable cultivation strategies in Mediterranean climates.…”
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Microbial community characteristics and environmental response of water bodies in different environmental areas underground coal mine by Haitao ZHANG, Guangquan XU, Xiaoqing CHEN, Xu LI, Zixuan LI, Yanxi ZHANG, Gang ZHANG, Jianghui HE

“…These functions maintained the ecological balance of underground water bodies in coal mines and played an important role in regulating and restoring ecosystems.…”
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Transforming Bone Tunnel Evaluation in Anterior Cruciate Ligament Reconstruction: Introducing a Novel Deep Learning System and the TB-Seg Dataset by Ke Xie, Mingqian Yu, Jeremy Ho-Pak Liu, Qixiang Ma, Limin Zou, Gene Chi-Wai Man, Jiankun Xu, Patrick Shu-Hang Yung, Zheng Li, Michael Tim-Yun Ong

“…Evaluating bone tunnels is crucial for assessing functional recovery after anterior cruciate ligament reconstruction. …”
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Visualization of four-dimensional X-ray absorption fine structure data using a virtual reality system by Haruo Igarashi, Daiki Kido, Yutaka Ishii, Yasuhiro Niwa, Atsushi Okamoto, Masao Kimura

“…Our 4D-XASView facilitates the visualization and analysis of the geometric and topological aspects of the data using VR goggles, enabling detailed exploration of microstructures via rotation and zooming functionalities. This capability allows us to extract XAFS spectral data by selecting specific positions and regions, thereby aiding in the identification of `trigger sites' (magnetite in serpentine), which are characteristic locations within materials that substantially influence the macroscopic propagation of reactions. …”
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Current Perspectives on Anorexia Nervosa in Health and Therapy - a review by Wojciech Bieńkowski, Julia Charkot, bartlomiej kusy, Michał Bieńkowski, Mikołaj Charkot, Piotr Kucharczyk, Irmina Jaszczuk, Patrycja Retman

“…Material and method: A narrative literature review was conducted using publications from 2010 to 2024, sourced from databases such as PubMed, Scopus, and Web of Science. …”
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Neonatal Microcephaly and Central Nervous System Abnormalities During the Zika Outbreak in Rio de Janeiro by Marlos Melo Martins, Roberto de Andrade Medronho, Carlos Eduardo Raymundo, Arnaldo Prata-Barbosa, Antonio José Ledo Alves da Cunha

“…Ophthalmologic abnormalities were detected in 55.5% of cases, and brainstem auditory evoked potential anomalies were reported in 33.3%. …”
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Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress by Lauren A. Hennessy, Bhedita J. Seewoo, Liz A. Jaeschke, Leah A. Mackie, Abbey Figliomeni, Yasmin Arena-Foster, Sarah J. Etherington, Sarah A. Dunlop, Paul E. Croarkin, Jennifer Rodger

“…Behaviour was assessed using the Elevated Plus Maze and Forced Swim Test, and functional, chemical, and structural brain changes measured using magnetic resonance imaging techniques. …”
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The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota by Katsoulis-Dimitriou, Stefanos, Nikouli, Eleni, Gkalogianni, Elli Zafeiria, Karapanagiotidis, Ioannis T., Kormas, Konstantinos A.

“…This suggests that a new gut microbiota profile was selected due to the microalgae inclusion in the provided diet. …”
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Effects of Soil Texture on Effective Mixing Depth and Solute Loss by WANG Jie, ZHENG Hao, LI Zihan, REN Shaocong, WANG Shuoguo, LIAN Qijie, WEI Yujie, CAI Chongfa

“…It is of great significance to quantify the effective mixing depth of texture-differentiated soils and investigate the response of effective mixing depth to soil erosion, and solute loss in the modeling of agricultural non-point source pollution. ［Methods］ The topsoils of five texturally distinct dry croplands in the Danjiangkou Reservoir Region were selected as the research object. …”
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A novel acidic laminarinase derived from Jermuk hot spring metagenome by Ani Paloyan, Tigran Soghomonyan, Mariam Karapetyan, Hasmik Grigoryan, Anna Krüger, Fiona Cuskin, Jon Marles-Wright, Christin Burkhardt, Garabed Antranikian

“…Abstract Laminarinase, an enzyme with a specific affinity for laminarin—a complex polysaccharide found in the cell walls of brown algae and select marine organisms—was investigated in this study. …”
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Machine learning prediction of pKa of organic acids by Juda Baikété, Alhadji Malloum, Jeanet Conradie

“…Further molecular descriptors have been generated using density functional theory (DFT) calculations, and RDKit library. …”
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Environmental impact assessment of maize cultivation system considering different irrigation methods by Filippo Vigo, Michele Zoli, Daniela Lovarelli, Jacopo Bacenetti

“…One ton of ear maize silage at 48% moisture content was selected as functional unit and a “from cradle to farm gate” was considered as system boundary . …”
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