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An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment
Published 2025-01-01“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
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circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p
Published 2022-01-01“…Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers, accounting for around 80% of total lung cancer cases worldwide. Exploring the function and mechanism of circRNAs could provide insights into the diagnosis and treatment for NSCLC. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development
Published 2025-08-01“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging
Published 2025-05-01“…Further analysis of the mutant flies revealed that sets of odorant receptor (OR) genes were differentially expressed. Functional characterization of the differentially expressed ORs suggested that sulfakinin directly suppresses the expression of ORs that respond to opposite-sex hormones while enhancing the expression of ORs that detect food volatiles. …”
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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro
Published 2024-12-01“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT
Published 2025-05-01“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images
Published 2025-05-01“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin
Published 2025-10-01Get full text
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WHSC1/NSD2 regulates immune infiltration in prostate cancer
Published 2021-02-01Get full text
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PhenoVision: A framework for automating and delivering research‐ready plant phenology data from field images
Published 2025-08-01“…We close by discussing next steps, including automating phenology annotations, adding new phenology targets, for example leaf phenology, and further integration with other resources to form a global central database integrating all in situ plant phenology resources.…”
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Diverse ancestral representation improves genetic intolerance metrics
Published 2025-03-01“…These findings highlight the need for enhanced population representation in genomic resources to fully realize the potential of precision medicine and drug discovery. …”
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DistB-Condo: Distributed Blockchain-Based IoT-SDN Model for Smart Condominium
Published 2020-01-01“…Condominium network refers to intra-organization networks, where smart buildings or apartments are connected and share resources over the network. Secured communication platform or channel has been highlighted as a key requirement for a reliable condominium which can be ensured by the utilization of the advanced techniques and platforms like Software-Defined Network (SDN), Network Function Virtualization (NFV) and Blockchain (BC). …”
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