Assessing the Influence of Selected Permeabilization Methods on Lymphocyte Single-Cell Multi-Omics by Shifan Ding, Na Lu, Hassan Abolhassani

“…(1) Background: Single-cell multi-omics is a powerful method for the dissection and detection of complicated immunologic functions and synapses. …”
Get full text

Near-infrared spectroscopy of the cerebellum in motor activation tasks by Yew Long Lo, Gerald Teck Heng Chia, Yan Teng Celeste Chen, Eng King Tan

“…Protocol 1 consisted of 5 optodes (4 sources and 1 detector, 4 recording channels) spaced 3 cm apart and comprising single-tipped LED light sources in conjunction with single-tipped fiber-optic detectors. …”
Get full text

New Rotation Periods from the Kepler Bonus Background Light Curves by Zachary R. Claytor, Jamie Tayar

“…However, due to Kepler’s large 4″ pixels, many of its light curves are at high risk of contamination from background sources. The new Kepler Bonus Background light curves are deblended using a point-spread function algorithm, providing light curves of over 400,000 new background sources in addition to over 200,000 reanalyzed Kepler prime targets. …”
Get full text

THE SOLUTION TO THE EQUATION OF THE SHOCK WAVE BURGERS IN THE PTC MATHCAD ENVIRONMENT by R. E. Oleynikova

“…However, this error is detected through the values of the nonlinear term included in the differential equation, which is determined according to the binomial representation through the quadratic forms of the matrix of the trial function. …”
Get full text

Safety and Probiotic Evaluation of Lactiplantibacillus plantarum CHEN1 and Its Metabolic Analysis of Soymilk Oligosaccharides by Zhina CHEN, Shiyi CAO, Linlin YIN, Mengyuan SHAO, Tao YE, Zhangrui XU, Xiaochen HUANG

“…The genetic characteristics of the strain were analyzed through genome sequencing and functional annotation. Phenotypic experiments, including hemolytic activity assays, detection of harmful metabolites, antibiotic susceptibility testing, tolerance experiments, hydrophobicity, and autoaggregation assays were conducted to evaluate its safety and probiotic potential. …”
Get full text

Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
Get full text

Real-World Efficacy of Explainable Artificial Intelligence using the SAGE Framework and Scenario-Based Design by Eleanor Mill, Wolfgang Garn, Chris Turner

“…The first of its kind, it leverages three distinct but complementary frameworks to support a user-centric and context-sensitive, post-hoc explanation for fraud detection. Using the principles of scenario-based design, it amalgamates two independent real-world sources to establish a realistic card fraud prediction scenario. …”
Get full text

Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
Get full text

Protocol Biopsies in Kidney Transplant Recipients: Current Practice After Much Discussion by Christina Lazarou, Eleni Moysidou, Michalis Christodoulou, Stamatia Stai, Georgios Lioulios, Efstratios Kasimatis, Asimina Fylaktou, Maria Stangou

“…Expert opinion and consensus acknowledge the benefits of protocol biopsies for early detection and tailored management but also highlight ongoing debates regarding their routine use in low-risk patients due to risks, costs, and resource considerations. …”
Get full text

Association of Omega-3 Index and Blood Cell Count-Derived Systemic Inflammatory Indexes among Testicular Germ Cell Tumor Survivors by Milica Zeković, Marko Živković, Marija Takić, Sanja Stanković, Nebojša Bojanić, Aleksandar Janičić, Uroš Bumbaširević

“…Background and objectives: Although testicular cancer is considered the paradigm of highly curable malignancy, treatment-induced adverse effects and potential impairment of gonadal function may cause non-negligible long-term health repercussions, including metabolic disturbances and cardiovascular sequelae. …”
Get full text

Life-threatening bleeding with intussusception due to gastrointestinal stromal tumor: a case report by Min Sung Kim, In Teak Woo, Young Min Jo, Jin Hyung Lee, Byung Sam Park

“…Abstract Background Massive intraluminal bleeding requires urgent intervention and management. However, the source of bleeding on the small intestine is difficult to determine. …”
Get full text

Venous Thromboembolism Prophylaxis in Intensive Care Units (Review) by L. V. Popova, T. B. Kondratieva, M. Z. Kanevskaya, T. L. Aleinikova, E. S. Zykova, А. V. Krivova, A. M. Kuznetsov

“…VTE is common and potentially life-threatening in patients admitted to ICU, even in spite of preventive care.The purpose of the review is to justify the necessity of preventive care for venous thromboembolism in ICU patients.From over 300 initially selected sources of literature databases (Scopus, Web of science, RSCI, etc.), 99 sources were chosen including 69 that were published during the last five years (2015-2020). …”
Get full text

Glyceraldehyde-3-phosphate dehydrogenase acts as a mitochondrial trans-S-nitrosylase in the heart. by Mark J Kohr, Elizabeth Murphy, Charles Steenbergen

“…Mitochondrial proteins have been shown to be common targets of S-nitrosylation (SNO), but the existence of a mitochondrial source of nitric oxide remains controversial. SNO is a nitric oxide-dependent thiol modification that can regulate protein function. …”
Get full text

Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee... by Bahia Moustafa, Neveen A. Soliman, Ihab Shaheen, Ahmed Badr, Fatma M. Atia, Mohamed K. El Hatw, Engy Adel Mogahed, Mona EL-Ghamrawy, Khaled El Khashab, Noha Shaheen, Mohamad G. Shouman, Abeer Selim, Magdy El-Sharkawy, Tarek Abd El Azeem, Mohamad Esmat, Manal Salman, Bedeir Ali-El-Dein, Mona Abdel Rahim, Muhamed A. El-Hadedy, Moatasem Elsayed Ghoneim, Mai S. Korkor, Tarek E. I. Omar, Yasser Amer, Ashraf Abdel Baky, On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee

“…Infections, rejection, recurrence, malignancy, bone problems, hypertension, and surgical complications are the most important challenges that require prevention, early detection, and management. Chronic allograft nephropathy needs different approaches based on its related causes, allograft pathology, graft function, and availability of re-transplantation. …”
Get full text

Implementation of stochastic signal processing algorithms in radar CAD by M. Yu. Konopel'kin, S. V. Petrov, D. A. Smirnyagina

“…A simulation model of a sector surveillance radar with a digital antenna array was created in the radar CAD visual functional editor. The passive channel included the following algorithms: algorithm for detecting stochastic signals; algorithm for estimating the number of stochastic signals; direction finding algorithm for stochastic signal sources; adaptive spatial filtering algorithm. …”
Get full text

Combining dopamine and glucose sensings on paper devices for the metabolic study of neurosecretion by Rémi F. Dutheil, Dabeaurard Tho, Iman Pitroipa, Raphaël Trouillon

“…Glucose, the main source of energy of the human body, and dopamine, a major neurotransmitter, are two analytes widely investigated in the study of the brain. …”
Get full text

A novel approach to field data augmentation with remote sensing and machine learning in rangelands by Hailey E. Schmidt, Javier Osorio Leyton, Efrain Noa Yarasca, Sorin C. Popescu, Justinn J. Jones, Justin P. Wied, Xinyuan Wu

“…However, these ecosystems are increasingly threatened by woody plant encroachment (WPE), which impacts forage availability, habitat quality, and other ecosystem functions. Despite advances in remote sensing and machine learning (ML) for monitoring and managing WPE, a significant gap persists in providing effective, scalable, and high-quality training data to support early detection efforts. …”
Get full text

Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC) Quantitative Analysis of L-Arginine in Freeze-Dried Red Dragon Fruits (<i>Hylocereus polyhizus</i>) by Wan Mazlina Md Saad, Mohd Qamarul Aizat Isha, Muhamad Faizzudin Mohamad Zan, Siti Mastura Hanim Sallehoddin

“…Thus, this study opens further avenues toward exploring red dragon fruit as a natural source of L-arginine and advancing functional and nutraceutical products.…”
Get full text

Comparative genomics reveals key adaptive mechanisms in pathogen host-niche specialization by Menglu Zhang, Longxi Han, Caizhi Liao, Weiheng Su, Weiheng Su, Chunlai Jiang, Chunlai Jiang

“…Bacteria from clinical settings had higher detection rates of antibiotic resistance genes, particularly those related to fluoroquinolone resistance. …”
Get full text

Synovial cesys in children: clinical features, diagnostics, treatment (analytical review of the literature and own observation) by V.S. Konoplitskyi, Yu. Ye. Korobko, B.L. Pavlenko, H.M. Rudenko, O.A. Korobko, S.V. Klymenko

“…Thus, according to literature sources, the frequency of pathology in patients under 20 years of age reaches 10% in the population and less than 2% in children under 10 years of age. …”
Get full text