Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Weekly online assessments of mood and anxiety from randomisation to week 52, with psychosocial function, quality of life and healthcare resource utilisation assessments conducted at regular intervals. …”
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The 4–400 GHz Survey for the 32 Class II Disks in the Taurus Molecular Cloud by Chia-Ying Chung, An-Li Tsai, Melvyn Wright, Wenrui Xu, Feng Long, Mark A. Gurwell, Hauyu Baobab Liu

“…We have compiled the ∼4–400 GHz broad spectra of 32 Class II protoplanetary disks (PPDs) in the Taurus-Auriga region, which represents the brightest one-third of sources detected in the submillimeter band in this region. …”
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Direction of Arrival Estimation Based on the Multistage Nested Wiener Filter by Xiaodong He, Bin Tang

“…The computation of the proposed method is simple, and the number of detectable signal sources could exceed the number of antenna elements.…”
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Near-infrared spectroscopy of the cerebellum in motor activation tasks by Yew Long Lo, Gerald Teck Heng Chia, Yan Teng Celeste Chen, Eng King Tan

“…Protocol 1 consisted of 5 optodes (4 sources and 1 detector, 4 recording channels) spaced 3 cm apart and comprising single-tipped LED light sources in conjunction with single-tipped fiber-optic detectors. …”
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New Rotation Periods from the Kepler Bonus Background Light Curves by Zachary R. Claytor, Jamie Tayar

“…However, due to Kepler’s large 4″ pixels, many of its light curves are at high risk of contamination from background sources. The new Kepler Bonus Background light curves are deblended using a point-spread function algorithm, providing light curves of over 400,000 new background sources in addition to over 200,000 reanalyzed Kepler prime targets. …”
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Connectivity guided intermittent theta burst stimulation versus repetitive transcranial magnetic stimulation in moderately severe treatment resistant depression by Richard Morriss, Lucy Webster, Luke Ingram, Mohamed Abdelghani, Adriana Anton, Shaun Barber, Peter Bates, Paul Briley, Clement Boutry, Cassandra Brookes, Edward Cox, Beth Hall, Marilyn James, Matthew Keane, Micheal Kurkar, Sudheer Lankappa, Peter Liddle, Hamish McAllister-Williams, Hyerin Oh, Alexander O’Neill-Kerr, Jehill Parikh, Stefan Pszczolkowski, Ana Suazo Di Paola, Louise Thomson, Yvette Walters, Dorothee Auer

“…Health-related quality of life (HRQoL), health service resource use and broader societal costs were collected at baseline and 16 and 26 weeks for assessing the cost-effectiveness of cgiTBS and rTMS to the NHS. …”
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Bronchial asthma in children of Ukraine: medical and environmental parallels of morbidity and prevalence by O. P. Volosovets, Y. K. Bolbot, S. P. Kryvopustov, O. V. Mozyrska, M. V. Kryvopustova, M. P. Prokhorova, A. V. Kupkina

“…Over the past 25 years in Ukraine there has been 69.3% increase in prevalence and 22.9% increase in incidence of bronchial asthma among children. Predominance of detecting this pathology was in the group of children from large industrial and agro-industrial regions of the country with significant volumes of atmospheric pollutants from stationary sources of pollution.…”
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Molecular organization of the nanoscale surface structures of the dragonfly Hemianax papuensis wing epicuticle. by Elena P Ivanova, Song Ha Nguyen, Hayden K Webb, Jafar Hasan, Vi Khanh Truong, Robert N Lamb, Xiaofei Duan, Mark J Tobin, Peter J Mahon, Russell J Crawford

“…The molecular organization of the epicuticle (the outermost layer) of insect wings is vital in the formation of the nanoscale surface patterns that are responsible for bestowing remarkable functional properties. Using a combination of spectroscopic and chromatographic techniques, including Synchrotron-sourced Fourier-transform infrared microspectroscopy (FTIR), x-ray photoelectron spectroscopy (XPS) depth profiling and gas chromatography-mass spectrometry (GCMS), we have identified the chemical components that constitute the nanoscale structures on the surface of the wings of the dragonfly, Hemianax papuensis. …”
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Presepsin as a sepsis biomarker by K. A. Trunova

“…Presepsin was highly  sensitive in detecting late neonatal sepsis, burn sepsis, and also reflected the efficacy of therapy  in septic premature babies and severely burned patients. …”
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The Diversity of Cold Worlds: A Blended-light Binary Straddling the T/Y Transition in Brown Dwarfs by Daniella C. Bardalez Gagliuffi, Jacqueline K. Faherty, Genaro Suárez, Sherelyn Alejandro Merchan, Brianna Lacy, Ben Burningham, Klara Matuszewska, Rocio Kiman, Johanna M. Vos, Austin Rothermich, Jonathan Gagné, Caroline Morley, Melanie J. Rowland, Dan Caselden, Aaron Meisner, Adam C. Schneider, Marc J. Kuchner, Charles A. Beichman, Peter R. Eisenhardt, Christopher R. Gelino, Ehsan Gharib-Nezhad, Eileen C. Gonzales, Federico Marocco, Niall Whiteford, J. Davy Kirkpatrick

“…Carbon disequilibrium chemistry strongly shapes the mid-infrared spectra of these sources, as a complex function of the metallicity and surface gravity. …”
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Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics by Haiting Huang, Yu Liu, Jianmu Su, Xiangxiu Liang, Hong Wu, Mei Bai

“…Flavonoids related to medicinal effects, such as naringin and hesperidin, were significantly more abundant in Huazhou pomelo than in Sanhong pomelo, with compounds such as 5-demethylnobiletin detected only in Huazhou pomelo. The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Who Leads Trends on Q&A Platforms? Identifying and Analyzing Trend Discoverers by Yongning Li, Lun Zhang, Ye Wu, Tianlan Wei

“…Q&A platforms are vital sources of information but often face challenges related to their high ratios of passive to active contributors, which can impede knowledge construction and information exchange on the platforms. …”
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Unlocking the potential of circulating small extracellular vesicles in neurodegenerative disease through targeted biomarkers and advancements in biosensing by Saqer Al Abdullah, Ivy Cocklereece, Kristen Dellinger

“…Neurodegenerative diseases (NDDs) gradually affect neurons impacting both their function and structure, and they afflict millions worldwide. …”
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New Thermoelectric Sensor Adapted to Realize an Infrared Radiations Detector by Mohammed Rahmoun, Khalid Hachami, Abdelwahad Touil, Benaissa Bellach, Mohammed Bailich, Ammar Merdani

“…The present paper deals with the design and the realization of a new thermoelectric sensor (Seebeck), sensitive to the infrared radiations emitted by different sources. The function mechanism utilizes radiative absorption phenomena, heat transfer, and thermoelectric effects. …”
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Leveraging artificial intelligence for photo identification to aid CITES enforcement in combating illegal trade of the endangered humphead wrasse (Cheilinus undulatus) by C. Y. Hau, W. K. Ngan, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson, Y. Sadovy de Mitcheson

“…The application compares and detects changes in fish individuals at each location. …”
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Mid-infrared Ensemble Variability of Broad-line and Narrow-line Seyfert 1 Galaxies by Zhipeng Hu, Lisheng Mao

“…The MIR variability of the combined sample is positively correlated with black hole mass and the FWHM of the H β emission line at long rest-frame time lags. (4) The long-term MIR variability of the combined sample may be mainly driven by the Eddington ratio. (5) For BLSy1 galaxies, the MIR variability of radio-detected sources is greater than that of radio-undetected sources, whereas for NLSy1 galaxies, the opposite is true.…”
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Venous Thromboembolism Prophylaxis in Intensive Care Units (Review) by L. V. Popova, T. B. Kondratieva, M. Z. Kanevskaya, T. L. Aleinikova, E. S. Zykova, А. V. Krivova, A. M. Kuznetsov

“…VTE is common and potentially life-threatening in patients admitted to ICU, even in spite of preventive care.The purpose of the review is to justify the necessity of preventive care for venous thromboembolism in ICU patients.From over 300 initially selected sources of literature databases (Scopus, Web of science, RSCI, etc.), 99 sources were chosen including 69 that were published during the last five years (2015-2020). …”
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Elevated heterotrophic activity in Guaymas Basin hydrothermal plumes influences deep-sea carbon cycling by Andrew Montgomery, Guang-Chao Zhuang, Zhichao Zhou, Marguerite V. Langwig, María del Carmen Millán-Motolinía, Hannah Y. L. Choi, Kimberley S. Hunter, Carlos A. Mortera-Gutiérrez, Christelle Hyacinthe, Zachary Marinelli, Karthik Anantharaman, Andreas Teske, Samantha B. Joye

“…Metatranscriptomic analysis of functional genes for heterotrophic metabolisms implicates Gammaproteobacteria and diverse heterotrophs in hydrothermally-sourced organic carbon degradation. …”
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SIMPLE: Simple Intensity Map Producer for Line Emission by Maja Lujan Niemeyer, José Luis Bernal, Eiichiro Komatsu

“…Simple can be applied to any spectral line sourced by galaxies. The Simple code is based on lognormal mock catalogs of galaxies including positions and velocities and assigns luminosities following the luminosity function. …”
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