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Milk phenomics: leveraging biological bonds with blood and infrared technologies for evaluating animal nutritional and health status
Published 2024-12-01“…Indeed, monitoring the nutritional and health status becomes paramount, aiming for an early detection of (sub)clinical health impairments. Given the mammary gland’s centrality in high-yielding dairy breeds, it’s unsurprising that the milk matrix provides insights about udder itself but also systemic metabolic function. …”
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1363
Optimizing extraction of microbial DNA from urine: Advancing urinary microbiome research in bladder cancer
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1364
Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy
Published 2025-07-01“…Understanding these structures provides insights into their functional roles. While super-resolution microscopy can visualise such patterns, manual detection in large datasets is challenging and biased. …”
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1365
GENERATION AND COLLECTION OF TOBACCO AEROSOL FOR SHISHA
Published 2020-11-01“…Qualitative characteristics of tobacco aerosol for shisha are determined by the functional purpose and depend on the component composition of the tobacco mixture and the coal used.The purpose of the research is to develop a methodology for the comprehensive assessment of tobacco for shisha based on modern methods of product quality control and includes the following steps:- monitoring of the studies to determine the component composition of the hookah mixture and the aerosol produced;- analysis of hookah mixture testing modes and development of an aerosol generation protocol;- development of a method for collecting aerosol on a laboratory smoking machine; - quantitative analysis of toxic analytes by HPLC MS / MS method.Methods have been developed for the machine generation and collection of tobacco aerosol for hookah, taking into account low concentrations of the analyzed toxic substances.The expediency of using the HPLC MS / MS method to determine the quantity of the following substances in tobacco aerosol for shisha has been substantiated:- carbonyl compounds (formaldehyde, acetaldehyde, acrolein) by detection on an electrospray source in the negative polarity mode- tobacco specific nitrosoamines (NNN and NNK) by detection on an electrospray source in the positive polarity mode.During the research laboratory and analytical equipment was used: a five-channel linear CERULEAN SM 405 smoking machine; Thermo Scientific Dionex UltiMate 3000 liquid chromatograph and TSQ Quantiva mass spectrometer.Obtaining experimental data on the quantitative determination of the component composition of the aerosol produced by tobacco for shisha using hookah systems is relevant for assessing toxic characteristics of the product.…”
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1366
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Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China
Published 2025-08-01“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
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1368
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1369
Thrombus rooting in the pulmonary arteriovenous fistula in a patient with cryptogenic stroke, a case report
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1370
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1371
INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW)
Published 2019-12-01“…The peculiarities of their structure and relations are subordinated to their functioning as part of a single integral mechanism. …”
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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
Published 2025-03-01“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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1374
Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs
Published 2025-05-01“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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1375
Genomics and integrative clinical data machine learning scoring model to ascertain likely Lynch syndrome patients
Published 2025-05-01“…Annovar, Intervar, Variant Effect Predictor (VEP), and OncoKB software tools were used to functionally annotate and interpret somatic variants detected. …”
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Evaluation of the authenticity of Citri Grandis Exocarpium based on metabolomics and transcriptomics
Published 2025-01-01“…Flavonoids related to medicinal effects, such as naringin and hesperidin, were significantly more abundant in Huazhou pomelo than in Sanhong pomelo, with compounds such as 5-demethylnobiletin detected only in Huazhou pomelo. The integrative metabolomics and transcriptomics analysis identified 11 key structural genes and transcription factors potentially involved in flavonoid biosynthesis, providing candidate targets for functional validation. …”
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Phenolic Content, Antioxidant Activity and Quality Characteristics of Hulled Wheats Originating from Türkiye
Published 2025-07-01“…These findings demonstrate notable diversity among hulled wheats regarding the evaluated traits and suggest their potential as valuable genetic resources for wheat breeding programs.…”
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Lipidomic Profiling of Edible Japanese Sea Urchins by LC–MS
Published 2025-06-01Get full text
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