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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma
Published 2025-05-01“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care
Published 2024-12-01“…Objectives Microbial contamination of various accessory parts of the dental chair units (DCUs) is an essential source of cross infection, while the accessories of the crucial suction function are usually overlooked. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging
Published 2025-03-01“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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Whole blood RNA-seq analysis reveals the immunomodulatory effects of a supplemental multi-strain direct-fed microbial in the diet of newly weaned beef steers1
Published 2025-07-01“…In conclusion, this study revealed that beef steers fed the PRO additive exhibited differential expression of genes related to immune function and inflammatory response, suggesting an effect on immunity and stress resilience. …”
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Identification of multiple power quality disturbances in hybrid microgrid using deep stacked auto-encoder based bi-directional LSTM classifier
Published 2025-03-01“…In recent years microgrid technology has created widespread interest for the integration of renewable energy sources into main utility grid to supply clean energy to the end users. …”
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ParticleHolography.jl: Holographic particle measurement in Julia
Published 2025-02-01“…This comprehensive software provides an end-to-end processing pipeline encompassing a wide range of functionalities: preprocessing, including background removal and camera calibration; three-dimensional reconstruction through diffraction calculations; particle analysis, including detection and tracking; and result visualization. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment
Published 2025-06-01“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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Iodine deficiency as an environmental risk factor for thyroid gland diseases in animals
Published 2024-08-01“…Of all the organs of the endocrine system, the thyroid gland is the most closely related to the environment since its structure and function largely depend on the supply of iodine from the outside. …”
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Unraveling the microbiome–aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars
Published 2025-07-01Get full text
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Motivation and stimulation of employment specialists in the sphere of information technologies
Published 2016-04-01“…In conducting this study the main sources of raw data served as the information contained in scientific, reference, periodical literature on the subject in question, including the sources of information and telecommunications network "Internet". …”
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De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii
Published 2025-01-01“…Validation by BUSCO confirmed the high quality of our resources. Homology alignments of predicted ORFs showed that 21,842 sequences from Ae. mariae and 21,944 sequences from Ae. zammitii mapped to the Nr, SwissProt, and TrEMBL databases, while 19,208 and 19,393 predicted ORFs, respectively, were functionally annotated using the COG and KEGG databases. …”
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Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment
Published 2025-06-01“…A complementary approach using digital biomarkers to surpass exam-based limitations for detecting physical change coupled with a direct report from participants on what their sources of suffering are could be a useful advance in reporting beneficial effects of interventions, particularly if changes track together. …”
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Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms
Published 2025-12-01“…Moreover, integrating machine learning into risk management enhances decision-making by providing precise, data-driven predictions, allowing for more effective strategies and efficient resource allocation.Future research could incorporate additional data, such as historical records, economic indicators, and internal process information, to further improve prediction accuracy. …”
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Exploration of the interaction between antimicrobial peptides and gamma radiation for biosensor development.
Published 2025-06-01“…These findings indicate that, although AMPs demonstrate changes in activity as a function of dose and could be explored for biosensing, their functional stability is limited at higher radiation doses. …”
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Tracing the Earliest Stages of Star and Cluster Formation in 19 Nearby Galaxies with PHANGS-JWST and HST: Compact 3.3 μm Polycyclic Aromatic Hydrocarbon Emitters and Their Relation...
Published 2025-01-01“…We establish a selection criteria based on a median color threshold of F300M − F335M = 0.67 at F335M = 20 and identify 1816 sources. These sources are predominantly located in dust lanes, spiral arms, rings, and galaxy centers, with ∼87% showing concentration indices (CIs) similar to optically detected star clusters. …”
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