IT: An interpretable transformer model for Alzheimer's disease prediction based on PET/MR images by Zhaomin Yao, Weiming Xie, Jiaming Chen, Ying Zhan, Xiaodan Wu, Yingxin Dai, Yusong Pei, Zhiguo Wang, Guoxu Zhang

“…These insights significantly bolster the arsenal of tools available for AD diagnostics and contribute to the broader narrative of deciphering brain functionality through state-of-the-art imaging modalities.…”
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Quality evaluation of Polygonatum sibiricum slices from different regions based on appearance traits and multi-index metabolites combined with TOPSIS and gray relation analysis by Cheng Wang, Cheng Wang, Ju Ye, Sisi Jiang, Sisi Jiang, Xuguang He, Xuguang He, Min Ma, Min Ma, Li Yin

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Urinary Albumin-to-Creatinine Ratio (uACR) Point-of-Care (POC) Device with Seamless Data Transmission for Monitoring the Progression of Chronic Kidney Disease by Artitaya Thiengsusuk, Napaporn Youngvises, Runtikan Pochairach, Rehab Osman Taha, Kridsada Sirisabhabhorn, Nadda Muhamad, Wanchai Meesiri, Wanna Chaijaroenkul, Kesara Na-Bangchang

“…Its portability and cost-effectiveness make it particularly suitable for use in low-resource environments. Additionally, integrating uACR with eGFR enhances prognostic capabilities, offering a comprehensive approach to assessing kidney function and predicting CKD progression.…”
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Big data for imaging assessment in glaucoma by Douglas R. da Costa, Felipe A. Medeiros

“…Leveraging vast data sources, these technologies promise to enhance clinical practice and public health outcomes by enabling earlier disease detection, progression forecasting, and deeper understanding of underlying mechanisms. …”
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Establishment and characterization of liver‐specific Apoa4‐Cre and Cyp2c11‐Cre rat models in juvenile and adult stages by Wei Dong, Xiang Gao, Feifei Guan, Jirong Pan, Wei Chen, Li Zhang, Lianfeng Zhang

“…The use of floxed rat resource has rapidly increased, but the liver‐specific Cre rat lines for studying liver diseases and interested genes are limited, especially in a spatially and temporally restricted manner. …”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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Pathogenicity and virulence of Aeromonas schubertii in farmed Asian seabass (Lates calcarifer) in Thailand by Clara Trullàs, Sirikorn Kitiyodom, Komkiew Pinpimai, Putita Chokmangmeepisarn, Manoj Tukaram Kamble, Channarong Rodkhum, Nopadon Pirarat

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Distribution of β-casein variants and effects on milk composition in Podolian cows reared in Gargano Promontory (Southern Italy) by Antonella Santillo, Francesca d'Angelo, Cristina Lamberti, Maria Gabriella Giuffrida, Francesco Romaniello, Marzia Albenzio

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Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease. by Masayuki Fukumoto, Daisuke Miyamoto, Akihiko Soyama, Takanobu Hara, Yasuhiro Maruya, Peilin Li, Hajime Matsushima, Kazushige Migita, Takahiro Enjoji, Hanako Tetsuo, Takuro Fujita, Mampei Yamashita, Hajime Imamura, Tomohiko Adachi, Kengo Kanetaka, Takahiro Ochiya, Susumu Eguchi

“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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Bioactive matters based on natural product for cardiovascular diseases by Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou

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Energy filtering enables macromolecular MicroED data at sub-atomic resolution by Max T. B. Clabbers, Johan Hattne, Michael W. Martynowycz, Tamir Gonen

“…While direct electron detection essentially eliminates the read-out noise during MicroED data collection, other sources of noise remain and limit the measurement of faint high-resolution reflections. …”
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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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Optimizing maize germination forecasts with random forest and data fusion techniques by Lili Wu, Yuqing Xing, Kaiwen Yang, Wenqiang Li, Guangyue Ren, Debang Zhang, Huiping Fan

“…Traditional methods for detecting seed germination rates often involve lengthy experiments that result in damaged seeds. …”
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Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours by Tobias Åkerström, Branislav Klimàcek, Matilda Annebäck, Olov Norlén, Peter Stålberg

“…Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. …”
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Antioxidant Profiling of Botryocladia leptopoda Based on In Silico and In Vitro Studies by Fenny Crista Anastasia Panjaitan, Huey-Jine Chai

“…Thus, B. leptopoda can be considered a promising source of antioxidative products in the functional food and pharmaceutical industries.…”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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