Proteomic analysis of Buffalo milk somatic cells reveals metabolomic and immunological transitions during early lactation by Priyanka M. Kittur, Lija Satheesan, Narasimha Tanuj Gunturu, Yallappa M. Somagond, A. P. Madhusoodan, Ravi Kumar Gandham, Rani Alex, Ajay Kumar Dang

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Lipidomic Profiling of Edible Japanese Sea Urchins by LC–MS by Sahana Amai, Kisara Yuki, Siddabasave Gowda B. Gowda, Divyavani Gowda, Shu-Ping Hui

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Monitoring a New England Cottontail Reintroduction with Noninvasive Genetic Sampling by Melissa L. Bauer, Brett Ferry, Heidi Holman, Adrienne I. Kovach

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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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Analysis of variant interactions in families with autism points to genes involved in the development of the central nervous system. by Jacek Kaczyński, Marta Pasenkiewicz-Gierula

“…Analysis of the statistical interactions also points to genes whose biological functions are not yet known.…”
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High host specificity of alphacoronaviruses in Nearctic, insectivorous bats by Jonathon D. Kotwa, Arkadeb Bhuinya, Winfield Yim, Giulia Gallo, Pahul Singh, Qiang Liu, Anil Kumar, Emily Chien, Aaron Hou, Hsien-Yao Chee, Juliette Blais-Savoie, Lily Yip, Valerie Von Zuben, K. Aidan Wouters, Vikram Misra, Oliver Lung, Dalan Bailey, Finlay Maguire, Arinjay Banerjee, Samira Mubareka, Christina M. Davy

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Identification of WRKY gene family and analysis of drought stress expression in Poncirus polyandra by ZHANG Shanshan, RUAN Sunmei, YANG Wenzhong

“…This study provides new information for analysing the function of WRKY gene and its regulatory mechanism in response to drought stress in P. polyandra, and supplies excellent genetic resources for breeding drought-tolerant citrus varieties.…”
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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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Environmental Levels and Degradation Behavior of Pharmaceuticals and Personal Care Products (PPCPs) in the Water Environment by Zhaohe ZHANG, Dian CHEN, Wei ZHAO, Guoli YUAN, Jun LI, Xingchun JIAO

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Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad... by Fernanda Ginani, Diego Moura Soares, Carlos Augusto Galvão Barboza

“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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Balancing Performance and Portability: A Study on CsI(Tl) Crystal Sizes for Real-Time Gamma-Ray Spectrum and Dose Monitoring by Nikolaos Voulgaris, Hikari Nishimura, Shingo Tamaki, Sachie Kusaka, Isao Murata

“…This was accomplished by calculating the detection efficiency and energy resolution through experimental measurements using standard gamma-ray sources and simulations using MCNP5. …”
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Monitoring Diversity Profiles of Forested Landscapes in the Mediterranean Spain: Their Contribution to Local and Regional Vascular Plant Diversity by José M. García del Barrio, David Sánchez de Ron, Francisco Auñón, Raquel Benavides, Rafael Alonso Ponce, Sergio González-Ávila, Francisco Bolaños, Sonia Roig, Marta Ortega Quero

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Validation of a 60K SNP chip for caribou (Rangifer tarandus) for use in wildlife forensics, conservation, and management by Trottier-Lavoie Mallorie, Prunier Julien, Poisson William, Carrier Alexandra, Gilbert Isabelle, Mastromonaco Gabriela, Albert Vicky, Cecilia Hernandez, Bourret Vincent, Taillon Joëlle, Droit Arnaud, Côté Steeve D., Robert Claude

“…Based on a population-targeted subset of SNPs included in the chip design, reassignment of 981 samples to a functional group (here to a caribou ecotype) was highly accurate (99.59 %) and the relative probability of reassignment error was estimated using the logarithm of odds score. …”
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Comprehensive Evaluation of Chestnut Quality Based on Principal Component and Cluster Analysis by Yanqi YU, Mingyuan YANG, Chunmao LÜ, Shaoci BAI, Qunfang ZHANG, Chenyang ZOU, Han JIANG

“…To develop an appropriate method for evaluating the quality of chestnut resources. The 21 quality indicators of 25 chestnut varieties were detected and analyzed. …”
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Chromosome-Level Genome Assembly and Comparative Transcriptome Analyses Identified Energy Conservation as a Key Strategy for Anadromous Adaptation of the Hilsa Shad, <i>Tenualosa i... by Kishor Kumar Sarker, Liang Lu, Roland Nathan Mandal, Md Rashedur Rahman, Anirban Sarker, Mohammad Abdul Baki, Chenhong Li

“…Moreover, active gluconeogenesis and reduced insulin signaling in the liver are possibly linked to glucose homeostasis, potentially induced by prolonged starvation during migration. These genomic resources will accelerate the future evolutionary and functional genomics studies of <i>T. ilisha</i>.…”
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Predicting protein synergistic effect in Arabidopsis using epigenome profiling by Chih-Hung Hsieh, Ya-Ting Sabrina Chang, Ming-Ren Yen, Jo-Wei Allison Hsieh, Pao-Yang Chen

“…QHistone accurately identifies histone modifications associated with specific known proteins, and allows users to computationally validate their results using gene expression data from various plant tissues. These functions demonstrate an useful approach to utilizing epigenome data for gene regulation analysis, making QHistone a valuable resource for the scientific community ( https://qhistone.paoyang.ipmb.sinica.edu.tw ).…”
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Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing by Jiale Zhou, Ding Zhao, Jinze Li, Deqiang Kong, Xiangrui Li, Renquan Zhang, Yuru Liang, Xun Gao, Yuqiang Qian, Di Wang, Jiahui Chen, Liangxue Lai, Yang Han, Zhanjun Li

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