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1341
The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO3 membranes
Published 2025-05-01Get full text
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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin
Published 2025-10-01Get full text
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1345
Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin
Published 2025-12-01“…Background Rectal adenocarcinoma (READ) involves the dysregulated expression of alpha 2,8-Sialyltransferase1 (ST8Sia1) although its role during READ’s progression is unclear.Methods The mRNA level of ST8Sia1 was analyzed based on The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Tumor Immune Estimation Resource (TIMER) 2.0. Furthermore, the prognostic and significance of ST8Sia1 in READ was assessed through Kaplan-Meier curve, univariate, multivariate Cox regression, and receiver operating characteristic (ROC) methods. …”
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1346
Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
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1347
Clinical profile and molecular genetic analysis of alport syndrome in children: a single center experience
Published 2024-12-01“…Genetic testing emerged as a critical resource for diagnosing AS. Furthermore, early diagnosis is crucial for implementing an appropriate management plan and assessing the prognosis.…”
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The Roles of Transcrustal Magma- and Fluid-Conducting Faults in the Formation of Mineral Deposits
Published 2025-05-01“…At hydrocarbon fields, they play extremely important roles in conductive and convective heat, as well as in mass transfer to the area of hydrocarbon generation, determining the relationship between the processes of lithogenesis and tectogenesis, and activating the generation of hydrocarbons from oil and gas source rock. Detection of TCMFCFs was carried out using MMSS (the method of microseismic sounding) and MTSM (the magnetotelluric sounding method), in combination with other geological and geophysical data. …”
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1350
Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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1351
NORDIC denoising on VASO data
Published 2025-01-01“…However, VASO comes along with another reduction in detection sensitivity. NOise Reduction with DIstribution Corrected (NORDIC) PCA (principal component analysis) is a denoising technique specifically aimed at suppressing thermal noise, which has proven useful for increasing the SNR of high-resolution functional data. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation
Published 2025-05-01“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Glucosylceramides containing very long-acyl-chain fatty acid are critical for cotton fiber elongation by influencing brassinosteroid synthesis and signaling
Published 2025-08-01“…Cotton fiber is one of the longest plant cells and sphingolipids are closely associated with the development of cotton fiber cells. However, their function in cotton fiber cell development and its action mechanism is unclear. …”
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Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice
Published 2025-07-01Get full text
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1356
Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors
Published 2025-05-01“…Then calculate the correlation function of the reconstructed signal echo and apply a smooth pseudo Wigner Ville distribution for time-frequency analysis. …”
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1357
Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples
Published 2025-03-01“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction
Published 2023-07-01“…Special research methods included the assessment of the state of the microbicidal function of neutrophilic granulocytes using reactive spontaneous (SSLCL) and zymosan-induced luminol-dependent chemiluminescence tests (ILZHL). …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis
Published 2025-08-01“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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