The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis by Lu Zhao, Xin Chen, Yanan Zhang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yang Li, Xiaodong Cheng, Xing Xie, Weiguo Lu, Junfen Xu

“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
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Bioactive matters based on natural product for cardiovascular diseases by Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou

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Pyruvate formate lyase regulates fermentation metabolism and virulence of Streptococcus suis by Qingying Fan, Haikun Wang, Shuo Yuan, Yingying Quan, Rishun Li, Li Yi, Aiqing Jia, Yuxin Wang, Yang Wang

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Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence by Viswanath Kumar Ganesan, S. Vinodh, Malolan Sundararaman, M. Vimala Rani, M. Mathirajan

“…The global market's increasing demand, diverse resource supply options, global competition, and environmental protection needs are driving organizations to adopt sustainable strategies. …”
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Does tinnitus and emotional distress influence central auditory processing? A comparison of acute and chronic tinnitus in normal-hearing individuals. by Qian Zhou, Wenling Jiang, Haibin Sheng, Qinjie Zhang, Dian Jin, Haifeng Li, Meiping Huang, Lu Yang, Yan Ren, Zhiwu Huang

“…<h4>Design</h4>This study compared the auditory afferent and efferent functions of normal-hearing patients with acute tinnitus, chronic tinnitus, and control group using gap detection test, the Mandarin Hearing in Noise Test (MHINT), and contralateral suppression of transient evoked otoacoustic emissions (TEOAEs).…”
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Consistent microbial insights across sequencing methods in soil studies: the role of reference taxonomies by Niranjana Rose Edwin, Aoife Duff, Coline Deveautour, Fiona Brennan, Florence Abram, Orla O'Sullivan

“…Our findings reveal that both methods offer moderately similar outcomes, providing consistent detection of major phyla, similar microbial community differentiation patterns, and largely identifying the same relationships between the phyla and nitrogen functions. …”
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Identification of key genes associated with mesocotyl length through a genome-wide association study in rice by Li Xue, Li Xue, Sen Wang, Sen Wang, Qiuyu Zhang, Qiuyu Zhang, Bing Han, Di Cui, Longzhi Han, Jianxin Deng, Xiaoding Ma

“…In this study, 300 rice germplasm resources with a wide range of sources were selected as experimental materials. …”
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Origami-Inspired Biosensors: Exploring Diverse Applications and Techniques for Shape-Changing Sensor Platforms by Shikha Patil, Shariq Suleman, Nigar Anzar, Jagriti Narang, Roberto Pilloton, Suna Timur, Emine Guler Celik, Chandra S. Pundir, Sudheesh K. Shukla

“…Paper and biological substrates like DNA have been integrated with origami techniques to develop biosensors with enhanced functionality. The incorporation of aptamer origami into both paper and DNA biosensors further increases sensitivity and specificity for target detection. …”
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Research on Buckwheat Weed Recognition in Multispectral UAV Images Based on MSU-Net by Jinlong Wu, Xin Wu, Ronghui Miao

“…The neuron death caused by the original ReLU activation function may lead to misidentification, so it was replaced by the Swish function to improve the adaptability to complex inputs. …”
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Melatonin: A Novel Indolamine in Oral Health and Disease by V. K. Chava, K. Sirisha

“…Recent studies, by Claustrat et al. (2005), detected few extrapineal sources of melatonin like retina, gastrointestinal tract, and salivary glands. …”
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LeafDPN: An Improved DPN Model for the Identification of Bacterial Blight in Soybean in Natural Environments by Rui Cong, Ying Xu, Hao Su, Jiaying Zhou, Yuxi Hu, Dawei Xin, Qingshan Chen, Rongsheng Zhu, Shuang Song

“…<i>glycinea</i>, is one of the most devastating diseases in soybean with significant yield losses ranging from 4% to 40%. The timely detection of BBS is the foundation for disease control. …”
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Assessing chronic obstructive pulmonary disease risk based on exhalation and cough sounds by Geyi Wen, Chenshuo Wang, Wei Zhao, Jinliang Meng, Yanyan Xu, Ruiqi Wang, Zijing Zeng

“…Following this, each individual completed pulmonary function tests and participated in questionnaire surveys. …”
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Application of microscopic smartphone attachment for remote preoperative lab testing by Kefan Song, Kefan Song, Alexander T. Adams, Alexander T. Adams

“…This device is designed to assist both healthcare providers in resource-limited settings and patients by offering a low-cost, portable diagnostic tool that enables both in-clinic and at-home testing.MethodsThe system was tested for adaptability and compatibility by transitioning from its original Android platform to an iOS platform. …”
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Adaptive conflict resolution for IoT transactions: A reinforcement learning-based hybrid validation protocol by Mohammad A. Al Khaldy, Ahmad Nabot, Ahmad al-Qerem, Issam Jebreen, Abdulbasit A. Darem, Asma A. Alhashmi, Mohammad Alauthman, Amjad Aldweesh

“…The RL-based mechanism continuously adapts decision-making by learning from system states, prioritizing transactions, and dynamically resolving conflicts using a reward function that accounts for key performance parameters, including the number of conflicting transactions, cost of aborting transactions, temporal validity constraints, and system resource utilization. …”
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Exploring the Medicinal Potential of <i>Taraxacum Kok-Saghyz</i> (<i>TKS</i>) Using Widely Targeted Metabolomics by Michele Tan, Jeffrey Shih-Chieh Chu, Daniel Robin Swiger

“…This study presents the first comprehensive metabolic profile of <i>TKS</i>, highlighting its potential value beyond rubber production. The detection of numerous therapeutic secondary metabolites supports its promise as a pharmaceutical and nutraceutical resource. …”
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Effects of Covid-19 Pandemic on School Dropout in Selected Primry Schools in Nyarusiza Sub-County Kisoro District. by Sibo, Dusabe Chris Jackson

“…Innovative approaches could be used such as applications of artificial intelligence in high-risk/high-traffic sites to enhance COVID-19 detection efficiency while protecting medical staff and the general public from cross-infections The government should establish a physical and automated platform for coordination and resource mobilization for support to the poor pupils and the most vulnerable groups affected by COVID-19-related lockdown.…”
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Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases by András Zeke, Tomas Bastys, Anita Alexa, Ágnes Garai, Bálint Mészáros, Klára Kirsch, Zsuzsanna Dosztányi, Olga V Kalinina, Attila Reményi

“…We used a structurally consistent model on kinase‐docking motif interactions to facilitate the discovery of short functional sites in the structurally flexible and functionally under‐explored part of the human proteome and applied experimental tools specifically tailored to detect low‐affinity protein–protein interactions for their validation in vitro and in cell‐based assays. …”
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Investigating the AGN-neutrino connection with public IceCube data by Kuhlmann Julian, Capel Francesca

“…We present the first application of a newly developed hierarchical Bayesian analysis framework for the detection of point-like sources of high-energy neutrinos. …”
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On the usage of artificial intelligence in leprosy care: A systematic literature review. by Hilson Gomes Vilar de Andrade, Elisson da Silva Rocha, Kayo H de Carvalho Monteiro, Cleber Matos de Morais, Danielle Christine Moura Dos Santos, Dimas Cassimiro Nascimento, Raphael A Dourado, Theo Lynn, Patricia Takako Endo

“…The persistent stigma and social exclusion associated with leprosy complicate eradication efforts exacerbate the wider challenges faced by NTDs in sourcing the necessary resources and attention for control and elimination. …”
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Ferro-aluminosilicate composite generated from coal gasification fine slag for the preconcentration and adsorptive removal of selected artificial sweeteners from water by Xoliswa Cingo, Azile Nqombolo, Buhle Xakalashe, Xolisa Goso, Luthando Nyaba, Odwa Mapazi, Philiswa Nosizo Nomngongo

“…Furthermore, converting CGFS into functional adsorbents aligns seamlessly with the principles of a circular economy, emphasising resource reutilization and sustainability. …”
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