Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…The material was a whole blood sample obtained from a woman with clinical manifestations of hereditary angioedema without a decrease in the levels and function of the C1 inhibitor. The research methods included whole exome sequencing, bioinformatic analysis of the KNG1 gene mutation using a number of databases and web resources. …”
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On Power-Off Temperature Attacks Potential Against Security Sensors by Maryam Esmaeilian, Vincent Beroulle, David Hély

“…Although numerous security sensors and attack detectors have been proposed in the literature to detect different sources of FIAs, it is crucial to ensure that these mechanisms themselves have not been tampered. …”
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Carbon-Based Nanoadsorbents for the Removal of Emerging Pollutants by M. Venkata Ratnam, P. Akilamudhan, K. Senthil Kumar, S. Narasimha Reddy, K. Nagamalleswara Rao, Feroz Shaik, D. M. Reddy Prasad

“…Emerging contaminants (ECs) are substances that have been detected in water but have not been thoroughly tested or regulated. …”
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Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins by Nan Li, Hongna Liu, Zhongxing Song, Rui Zhou, Zhishu Tang, Zhishu Tang, Hongbo Xu, Xinbo Shi, Yanru Liu, Jian Ni

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Ultra-high-energy γ-ray emission associated with the tail of a bow-shock pulsar wind nebula

“…The source energy spectrum extended up to 300 TeV, which was well fitted by a log-parabola function with N0 = (1.93 ± 0.23) × 10−16 TeV−1 cm−2 s−1, α = 2.14 ± 0.27, and β = 1.20 ± 0.41 at E0 = 30 TeV. …”
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An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…However, efficient and sensitive detection methods remain limited. In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. …”
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Transcriptome analysis of corpora lutea in domestic cats (Felis catus) reveals strong differences in gene expression of various hormones, hormone receptors and regulators across di... by Beate C. Braun, Michał M. Hryciuk, Dorina Meneghini

“…The findings suggest that domestic cat CLs could also be a source of adipokines such as adiponectin or APELA. …”
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Screening of anomalies in a double-stranded DNA via global electrical measurements by Sourav Kundu

“…We conduct two-terminal charge transport calculations to detect biological defects in three types of DNA sequences: periodic, quasi-periodic and random. …”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals by Edanur Güler–Ekmen, İsmail Çağrı Yılmaz, Talat Güler, Derya Güler, Mehtap Özçelik

“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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MULTI-MODEL STACK ENSEMBLE DEEP LEARNING APPROACH FOR MULTI-DISEASE PREDICTION IN HEALTHCARE APPLICATION by Bhaskar Adepu, T. Archana

“…These datasets serve two functions: improving illness prediction and examining large data reservoirs to identify previously unknown disease patterns. …”
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Substandard Language Phenomena in Artistic Discourse by Anzhelika V. Korolkova, Tatyana S. Novikova

“…The substandard is currently becoming a source of replenishment of the stylistically reduced layer of modern colloquial speech.…”
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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. by Michele Vacca, Simona D'Amore, Giusi Graziano, Andria D'Orazio, Marica Cariello, Vittoria Massafra, Lorena Salvatore, Nicola Martelli, Stefania Murzilli, Giuseppe Lo Sasso, Renato Mariani-Costantini, Antonio Moschetta

“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection. by Alex J McCarthy, David Negus, Patricia Martin, Catarina Pechincha, Eric Oswald, Richard A Stabler, Peter W Taylor

“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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Service-Chain-Driven Communication and Computing Integration Networking: A Case Study of Levee Piping Hazard Inspection via Remote Sensing by Jing Chen, Lyuzhou Gao, Hongquan Sun, Siquan Yang, Zhonggen Wang, Yuting Wan, Kedi Wang

“…Computing power network (CPN) is designed to utilize multi-dimensional resources to complete computing tasks. However, in practical applications, the CPN architecture has difficulty in coordinating cross-domain heterogeneous resources, making it impossible to achieve the real-time and high scalability requirements of computationally intensive and time-sensitive tasks such as levee piping hazard inspection via remote sensing in emergency scenarios. …”
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Epidemic Process of Haemophilus influenzae Infection in WHO Regions by S. O. Vysokochanskaya, S. Y. Kombarova, R. V. Polibin, A. A. Basov

“…Although Hib infection is classified as vaccine-preventable, WHO and CDC do not post annual incidence information on their resources, unlike other vaccine-preventable infections. …”
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Investigation of the Application of Machine Learning Algorithms in Credit Risk Assessment of Medium and Micro Enterprises by Yujie Zhao

“…Thus, this proposed method achieves 14.65% high-risk detection with 5.56% financial revisions for the industry considered by the data source.…”
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Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…ConclusionsIn clinical practice, our tool would enable the automated monitoring and detection of risk points throughout all clinical trial stages; accurately identify the most relevant trial procedure and function line; and notify quality management personnel, in real time, to take prompt actions and dynamically prevent the recurrence of quality issues.…”
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Research review of digital modeling technologies with 3D spatial visualization for pipelines by Xin LIU, Shengwen TU, Yanfang HOU, Dong LIN, Jie SHU, Yu TANG

“…These developments have resulted in more comprehensive functionalities for visualization systems and improved operational and maintenance efficiency. …”
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