Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy by Zachary F. Greenberg, Samantha Ali, Andrew Brock, Jinmai Jiang, Thomas D. Schmittgen, Song Han, Steven J. Hughes, Kiley S. Graim, Mei He

“…Through modelling the ATP6V0B cycling threshold, we reported 3 models with AUCs between 0.86 and 0.88, showcasing an enabling and clinically translatable liquid biopsy approach for early detection of pancreatic cancer using circulating EVs. …”
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Identification of lipid metabolism related immune markers in atherosclerosis through machine learning and experimental analysis by Hang Chen, Biao Wu, Biao Wu, Kunyu Guan, Liang Chen, Kangjie Chai, Maoji Ying, Dazhi Li, Weicheng Zhao

“…Through further differential analysis and screening using machine learning algorithms, APLNR, PCDH12, PODXL, SLC40A1, TM4SF18, and TNFRSF25 were identified as key diagnostic genes for atherosclerosis. …”
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Estimation of the aboveground carbon stocks based on tree species identification in Saihanba plantation forest by Ao Zhang, Xiaohong Wang, Xin Gu, Xiangyao Xu, Xintong Gao, Linlin Jiao

“…The results were shown that: 1) The identification effect of Scheme IV, as ascertained by screening three types of effective feature vectors based on the random forest algorithm, was the most effective, with an overall accuracy (OA) and kappa coefficient of 89.7% and 0.863, respectively. …”
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Machine learning with the body roundness index and associated indicators: a new approach to predicting metabolic syndrome by Yaxuan He, Zekai Chen, Zhaohui Tang, Yuexiang Qin, Fang Wang

“…Traditional invasive diagnostic methods are costly, inconvenient, and unsuitable for large-scale screening. Developing a non-invasive, accurate prediction model is clinically significant for early MetS detection and prevention. …”
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U-shaped relationship between frailty and non-HDL-cholesterol in the elderly: a cross-sectional study by Yu Pan, Yan Yuan, Juan Yang, Zhu Qing Feng, Xue Yin Tang, Yi Jiang, Gui Ming Hu, Jiang Chuan Dong

“…The variables underwent screening through Least Absolute Shrinkage and Selection Operator (LASSO) regression, univariate logistic regression, and Light Gradient Boosting Machine (LightGBM), with models developed through multivariate logistic regression and the LightGBM algorithm. …”
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Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech by Julianna Olah, Win Lee Edwin Wong, Atta-ul Raheem Rana Chaudhry, Omar Mena, Sunny X. Tang

“…Linguistic and paralinguistic features were extracted and ensemble learning algorithms (e.g., XGBoost) were used to train models. …”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…A high IoU value in medical imaging analysis reflects the model’s ability to accurately delineate object boundaries.ConclusionDeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. …”
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Prevention of Cardiometabolic Syndrome in Children and Adolescents Using Machine Learning and Noninvasive Factors: The CASPIAN-V Study by Hamid Reza Marateb, Mahsa Mansourian, Amirhossein Koochekian, Mehdi Shirzadi, Shadi Zamani, Marjan Mansourian, Miquel Angel Mañanas, Roya Kelishadi

“…We applied the XGBoost algorithm to analyze key noninvasive variables, including self-rated health, sunlight exposure, screen time, consanguinity, healthy and unhealthy dietary habits, discretionary salt and sugar consumption, birthweight, and birth order, father and mother education, oral hygiene behavior, and family history of dyslipidemia, obesity, hypertension, and diabetes using five-fold cross-validation. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. …”
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Retinal Microvascular Characteristics—Novel Risk Stratification in Cardiovascular Diseases by Alexandra Cristina Rusu, Klara Brînzaniuc, Grigore Tinica, Clément Germanese, Simona Irina Damian, Sofia Mihaela David, Raluca Ozana Chistol

“…This study aims to identify the retinal microvascular features associated with CHDs and evaluate their potential use in a CHD screening algorithm in conjunction with traditional risk factors. …”
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Combining first principles and machine learning for rapid assessment response of WO3 based gas sensors by Ran Zhang, Guo Chen, Shasha Gao, Lu Chen, Yongchao Cheng, Xiuquan Gu, Yue Wang

“…The collected data was subsequently utilized to develop a correlation model linking the multi-physical parameters to gas sensitive performance using intelligent algorithms. …”
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Robust Bi-CBMSegNet framework for advancing breast mass segmentation in mammography with a dual module encoder-decoder approach by Yu Wang, Mudassar Ali, Tariq Mahmood, Amjad Rehman, Tanzila Saba

“…Current target detection algorithms have limited applications and low accuracy. …”
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Combinations of multimodal neuroimaging biomarkers and cognitive test scores to identify patients with cognitive impairment by Yuriko Nakaoku, Soshiro Ogata, Kiyotaka Nemoto, Chikage Kakuta, Eri Kiyoshige, Kanako Teramoto, Kiyomasa Nakatsuka, Gantsetseg Ganbaatar, Masafumi Ihara, Kunihiro Nishimura

“…Finally, MCI identification models were developed using a penalized logistic regression model with an elastic net algorithm.ResultsAmong the 148 participants (mean age, 78.6 ± 5.2 years), 44.6% were identified as having MCI. …”
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Rapid Resilience Assessment and Weak Link Analysis of Power Systems Considering Uncertainties of Typhoon by Wenqing Ma, Xiaofu Xiong, Jian Wang

“…Second, for the resilience assessment process, the impact increment method is used to reduce the dimensionality of multiple fault state analysis in the power system, and resilience indexes are calculated by screening the contingency set based on depth-first traversal through a backtracking algorithm. …”
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Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. by Patrick Y Sips, Xu Shi, Gabriel Musso, Anjali K Nath, Yanbin Zhao, Jason Nielson, Jordan Morningstar, Amy E Kelly, Brittney Mikell, Eva Buys, Vikhyat Bebarta, Jared Rutter, V Jo Davisson, Sari Mahon, Matthew Brenner, Gerry R Boss, Randall T Peterson, Robert E Gerszten, Calum A MacRae

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Few-Shot Intelligent Anti-Jamming Access with Fast Convergence: A GAN-Enhanced Deep Reinforcement Learning Approach by Tianxiao Wang, Yingtao Niu, Zhanyang Zhou

“…The method constructs a Generative Adversarial Network (GAN) to learn the time–frequency distribution characteristics of short-period jamming and to generate high-fidelity mixed samples. Furthermore, it screens qualified samples using the Pearson correlation coefficient to form a sample set, which is input into the DQN network model for pre-training to expand the experience replay buffer, effectively improving the convergence speed and decision accuracy of DQN. …”
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An EfficientNet integrated ResNet deep network and explainable AI for breast lesion classification from ultrasound images by Kiran Jabeen, Muhammad Attique Khan, Ameer Hamza, Hussain Mobarak Albarakati, Shrooq Alsenan, Usman Tariq, Isaac Ofori

“…Explainable artificial intelligence‐based analysed the performance of trained models. After that, a new feature selection technique is proposed based on the cuckoo search algorithm called cuckoo search controlled standard error mean. …”
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Leveraging automated time-lapse microscopy coupled with deep learning to automate colony forming assay by Anusha Klett, Anusha Klett, Dennis Raith, Dennis Raith, Paula Silvestrini, Paula Silvestrini, Paula Silvestrini, Matías Stingl, Jonas Bermeitinger, Avani Sapre, Avani Sapre, Avani Sapre, Martin Condor, Roman Melachrinos, Mira Kusterer, Alexandra Brand, Guido Pisani, Guido Pisani, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Marie Follo, Marie Follo, Jesús Duque-Afonso, Roland Mertelsmann, Roland Mertelsmann

“…Brightfield images were used to train a YOLOv8 object detection network, achieving a mAP50 score of 86% for identifying single cells, clusters, and colonies, and 97% accuracy for Z-stack colony identification with a multi-object tracking algorithm. The detection model accurately identified the majority of objects in the dataset.ResultsThis AI-assisted CFA was successfully applied for density optimization, enabling the determination of seeding densities that maximize plating efficiency (PE), and for IC50 determination, offering an efficient, less labor-intensive method for testing drug concentrations. …”
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Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. by Katherine R Bull, Andrew J Rimmer, Owen M Siggs, Lisa A Miosge, Carla M Roots, Anselm Enders, Edward M Bertram, Tanya L Crockford, Belinda Whittle, Paul K Potter, Michelle M Simon, Ann-Marie Mallon, Steve D M Brown, Bruce Beutler, Christopher C Goodnow, Gerton Lunter, Richard J Cornall

“…Forward genetics screens with N-ethyl-N-nitrosourea (ENU) provide a powerful way to illuminate gene function and generate mouse models of human disease; however, the identification of causative mutations remains a limiting step. …”
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Artificial Intelligence Powered Automated and Early Diagnosis of Acute Lymphoblastic Leukemia Cancer in Histopathological Images: A Robust SqueezeNet-Enhanced Machine Learning Fram... by Vineet Mehan

“…The growing prevalence of acute lymphoblastic leukemia cancer worldwide underlines the critical need for early and more precise detection to counter this deadly disease. …”
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