Immunoglobulin G N-Glycosylation and Inflammatory Factors: Analysis of Biomarkers for the Diagnosis of Moyamoya Disease by Zan X, Liu C, Wang X, Sun S, Li Z, Zhang W, Sun T, Hao J, Zhang L

“…This research aimed to evaluate the diagnostic efficacy of IgG N-glycosylation for MMD.Methods: Ultra-high-performance liquid chromatography (UPLC) was employed to examine the properties of IgG N-glycans in blood samples from 116 patients with MMD and 126 controls, resulting in the quantitative determination of 24 initial glycan peaks (GP). Through the Lasso algorithm and multivariate logistic regression analysis, we constructed a diagnostic model based on initial glycans and related inflammatory factors to distinguish MMD patients from healthy individuals.Results: After adjusting for potential confounding variables, including age, fasting blood glucose (FBG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), neutrophil count (NEUT), and lymphocyte count (LYM), our study demonstrated significant differences in the characteristics of 6 initial glycans and 16 derived glycans between the MMD cohort and the healthy control group. …”
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The Effect of Arctic Sea‐Ice Loss on Extratropical Cyclones by Stephanie Hay, Matthew D. K. Priestley, Hao Yu, Jennifer L. Catto, James A. Screen

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Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer by Wang S, Ma C, Ren Z, Zhang Y, Hao K, Liu C, Xu L, He S, Zhang J

“…The signatures were screened in a discovery cohort of GC patients (n=55) and non-disease controls (n=46) using an integrated process, including high-throughput sequencing technology, screening using a complete bioinformatics algorithm, validation using RT-qPCR, and evaluation by constructing a diagnostic model. …”
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Research on Path Optimization of Vehicle-Drone Joint Distribution considering Customer Priority by Xiaoye Zhou, Yuhao Feng

“…Compared with the three algorithms and error analysis, the effectiveness of the model and the two-stage algorithm was verified. …”
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Optimization of the Canopy Three-Dimensional Reconstruction Method for Intercropped Soybeans and Early Yield Prediction by Xiuni Li, Menggen Chen, Shuyuan He, Xiangyao Xu, Panxia Shao, Yahan Su, Lingxiao He, Jia Qiao, Mei Xu, Yao Zhao, Wenyu Yang, Wouter H. Maes, Weiguo Liu

“…Point cloud preprocessing was refined through the application of secondary transformation matrices, color thresholding, statistical filtering, and scaling. Key algorithms—including the convex hull algorithm, voxel method, and 3D α-shape algorithm—were optimized using MATLAB, enabling the extraction of multi-dimensional canopy parameters. …”
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Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs: A WEB prediction approach. by Huaichuan Duan, Quanshan Shi, Xinru Yue, Zelan Zhang, Ling Liu, Yueteng Wang, Yujie Cao, Zuoxin Ou, Li Liang, Jianping Hu, Hubing Shi

“…Here, we first summarized and improved the open reading frame information of monkeypox, constructed the monkeypox inhibitor library and potential targets library by database research as well as literature search, combined with advanced protein modeling technologies (Sequence-based and AI algorithms-based homology modeling). …”
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Keypoint Detection Based on Curvature Grouping and Adaptive Sampling by Bifu Li, Yu Cheng, Weitong Li

“…In the keypoint detection algorithm, the farthest point sampling methods and random sampling methods are usually used to select candidate points, then keypoints are screened out from the neighborhood of the candidate points. …”
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Ways to predict interstitial lung disease in patients with systemic sclerosis: results of an observational study by D. V. Khorolsky, A. A. Klimenko, E. S. Pershina, N. M. Babadeva, A. A. Kondrashov, N. A. Shostak, E. P. Mikheeva, E. V. Zhilyaev

“…It is advisable to include these indicators in the algorithm for screening and monitoring patients with SSc.…”
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Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medici... by Yuan S, Zhang R, Zhu Z, Zhou X, Zhang H, Li X, Hao Y

“…We applied metabolomics to identify differential metabolites distinguishing these patterns.Methods: In this study, the first principal component was analyzed by the OPLS-DA model. The model quality was evaluated by 7-fold cross-validation, and the model validity was evaluated based on R²Y (interpretability of categorical variable Y) and Q² (predictability of the model), and the permutation test was used for further verification. …”
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Auxiliary Diagnosis of Breast Cancer Based on Machine Learning and Hybrid Strategy by Hua Chen, Kehui Mei, Yuan Zhou, Nan Wang, Guangxing Cai

“…In this paper, we take breast cancer as the research object, and pioneer a hybrid strategy to process the data, and combine the machine learning method to build a more accurate and efficient breast cancer auxiliary diagnosis model. …”
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Integrative machine learning and molecular simulation approaches identify GSK3β inhibitors for neurodegenerative disease therapy by Hassan H. Alhassan

“…Among all models, the Random Forest (RF) algorithm had the best prediction accuracy, with a value of 0.6832 on the test set and 0.7432 on the training set, and was employed to screen the target library of 11,032 phytochemicals. …”
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The impact of specialised gastroenterology services for pelvic radiation disease (PRD): Results from the prospective multi-centre EAGLE study. by John N Staffurth, Stephanie Sivell, Elin Baddeley, Sam Ahmedzai, H Jervoise Andreyev, Susan Campbell, Damian J J Farnell, Catherine Ferguson, John Green, Ann Muls, Raymond O'Shea, Sara Pickett, Lesley Smith, Sophia Taylor, Annmarie Nelson

“…All men completed a validated screening tool for late bowel effects (ALERT-B) and the Gastrointestinal Symptom Rating Score (GSRS); men with a positive score on ALERT-B were offered management following a peer reviewed algorithm for pelvic radiation disease (PRD). …”
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A machine learning approach to predict positive coronary artery calcium scores in individuals with diabetes: a cross-sectional analysis of ELSA-Brasil baseline data by J.L. Amorim, I.M. Bensenor, A.P. Alencar, A.C. Pereira, A.C. Goulart, P.A. Lotufo, I.S. Santos

“…We analyzed 25 sociodemographic, medical history, symptom-related, and laboratory variables from 585 participants from the São Paulo investigation center with CACS data and no overt cardiovascular disease at baseline. We used six ML algorithms to build models to identify individuals with positive CACS. …”
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GB-SAR Engineering Interference Suppression Method Integrating Amplitude-Phase Feature Analysis and Robust Regression by Wenting Zhang, Tao Lai, Yuanhui Mo, Haifeng Huang, Qingsong Wang, Zhihua Zhou

“…Subsequently, a two-stage suppression model based on robust estimation theory is developed to effectively suppress interference. …”
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Time-Distributed Vision Transformer Stacked With Transformer for Heart Failure Detection Based on Echocardiography Video by Mgs M. Luthfi Ramadhan, Adyatma W. A. Nugraha Yudha, Muhammad Febrian Rachmadi, Kevin Moses Hanky Jr Tandayu, Lies Dina Liastuti, Wisnu Jatmiko

“…This study proposed a novel deep learning model consisting of a time-distributed vision transformer stacked with a transformer. …”
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Predicting cardiotoxicity in drug development: A deep learning approach by Kaifeng Liu, Huizi Cui, Xiangyu Yu, Wannan Li, Weiwei Han

“…This study not only improved the predictive accuracy of cardiotoxicity models but also promoted a more reliable and scientifically interpretable method for drug safety assessment. …”
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Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort by Carlo Alberto Scirè, Alessandra Bortoluzzi, Micaela Fredi, Matthias Schneider, Veronica Codullo, Carlomaurizio Montecucco, Alain Meyer, Ilaria Cavazzana, Lorenzo Cavagna, Franco Franceschini, Andreas Schwarting, Konstantinos Triantafyllias, Gamal Chehab, Christina Düsing, Jutta Richter, Ettore Silvagni, Oliver Sander, Giovanni Zanframundo, Claudia Bracaglia, Matthieu Canuet, Stefano Ghio, Rebecca Fischer, Emiliano Marasco, Sezgin Sahin, Lisa Keller, Marianne Riou, Stefanie Keymel

“…The variables we identified could be used to implement a screening algorithm to identify patients with SLE at risk of developing PAH.…”
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A Cell Component-Related Prognostic Signature for Head and Neck Squamous Cell Carcinoma Based on the Tumor Microenvironment by Siyu Li, Yajun Gu, Junguo Wang, Dengbin Ma, Xiaoyun Qian, Xia Gao

“…In this study, we aimed to develop a cell component-related prognostic model based on TME. We screened cell component enrichments from samples in The Cancer Genome Atlas (TCGA) HNSCC cohort using the xCell algorithm. …”
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Acetic Acid Production from Aspergillus terreus Isolated from Some Agricultural Soils Collected from Selected Locations within the North Gondar Zone, Amhara Region, Ethiopia by Kidist Alemayehu, Tamene Milkessa Jiru, Nega Berhane

“…A sequence similarity of 98.5% to A. terreus isolate LL2 (KIA) was obtained by comparing the Aspergillus isolate to a reference sequence in the GenBank using the BLAST algorithm. It can be concluded from this study that A. terreus isolated from agricultural soil in the north Gondar zone of Ethiopia could produce more acetic acid using barely straw as a substrate.…”
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Risk factors for osteoporosis in men aged 40 years or older: the results of the program «Osteoscreening-Russia» by O. A. Nikitinskaya, N. V. Toroptsova, E. L. Nasonov

“…The survey was conducted using a unified questionnaire. Screening also involved a densitometric study of distal forearm bone mineral density using a peripheral X-ray osteodensitometer (Osteometer Meditech DTX-200). …”
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