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1101
Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke
Published 2025-08-01“…Functional enrichment, gene set enrichment analysis (GSEA), and protein–protein interaction (PPI) analyses were performed. Hub genes were screened using LASSO, RandomForest, and SVM-RFE algorithms. …”
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1102
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…The 10 MI-related hub MitoDEGs were then obtained by eight different algorithms. Immunoassays showed a significant increase in monocyte macrophage and T cell infiltration. …”
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1103
TikTok and Sound: Changing the ways of Creating, Promoting, Distributing and Listening to Music
Published 2022-12-01“…In this article I will explore the ways in which TikTok has made an “aural turn” (Abidin and Kaye 2021), and thus changed and influenced the processes of music-making, music listening and music promotion. …”
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1104
Machine learning for clustering and classification of early knee osteoarthritis using single-leg standing kinematics
Published 2025-03-01“…This study investigated the application of machine learning techniques to single-leg standing (SLS) kinematics to classify and predict EOA. (1) To identify distinct groups based on SLS kinematic patterns using unsupervised learning algorithms, (2) to develop supervised learning models to predict EOA status, and (3) to identify the most influential kinematic variables associated with EOA. …”
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1105
In the Refractory Hypertension “Labyrinth”. Focus on Primary Hyperaldosteronism
Published 2020-09-01“…It should not only have made the diagnosis easy, but it could have also absolutely justified the surgical tactics. …”
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1106
AI-driven biomarker discovery: enhancing precision in cancer diagnosis and prognosis
Published 2025-03-01“…Existing gaps include data quality, algorithmic transparency, and ethical concerns around privacy, among others. …”
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1107
Combining Near-Infrared Spectroscopy and Chemometrics for Rapid Recognition of an Hg-Contaminated Plant
Published 2016-01-01“…The NIRS measurements of impacted sample powders were collected in the mode of reflectance. The DUPLEX algorithm was utilized to split the NIRS data into representative training and test sets. …”
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1108
Estimation of potato leaf area index based on spectral information and Haralick textures from UAV hyperspectral images
Published 2024-11-01“…Three types of spectral data—original spectral reflectance (OSR), first-order differential spectral reflectance (FDSR), and vegetation indices (VIs)—along with three types of Haralick textures—simple, advanced, and higher-order—were analyzed for their correlation with LAI across multiple growth stages. A model for LAI estimation in potato at multiple growth stages based on spectral and textural features screened by the successive projection algorithm (SPA) was constructed using partial least squares regression (PLSR), random forest regression (RFR) and gaussian process regression (GPR) machine learning methods. …”
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1109
Geographic variation in secondary metabolites contents and their relationship with soil mineral elements in Pleuropterus multiflorum Thunb. from different regions
Published 2024-09-01“…Conversely, a positive correlation was found between the contents of elements Na, Ce, Ti, and physcion and THSG-5, 2 components that exhibited higher levels in Deqing. Furthermore, an RF algorithm was employed to establish an interrelationship model, effectively forecasting the abundance of the majority of differential metabolites in HSW samples based on the content data of soil mineral elements. …”
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1110
The two ends of the spectrum: comparing chronic schizophrenia and premorbid latent schizotypy by actigraphy
Published 2025-05-01“…By applying model-explaining tools to the well-performing models, we could conclude the movement patterns and characteristics of the groups. …”
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1111
Deciphering the role of cuproptosis in the development of intimal hyperplasia in rat carotid arteries using single cell analysis and machine learning techniques
Published 2025-02-01“…Methods: We downloaded single-cell sequencing and bulk transcriptome data from the GEO database to screen for copper-growth-associated genes (CAGs) using machine-learning algorithms, including Random Forest and Support Vector Machine. …”
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1112
Polygraph and audio synchronization applied to apnea event analysis based on non-negative matrix factorization
Published 2025-06-01“…The proposed method introduces an iterative time-alignment algorithm based on the cross-correlation between an estimated respiratory sound signal and the nasal flow signal from PG. …”
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1113
Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation
Published 2025-07-01“…Functional enrichment (GO/KEGG), protein-protein interaction (PPI) networks, and machine learning algorithms were applied to screen hub genes, validated by ROC curves. …”
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1114
Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology
Published 2025-01-01“…This approach works under the assumption of conserved binding: when a larger molecule is designed containing the initial fragment hit, the common substructure between the two will adopt the same binding mode. Fragmenstein either takes the atomic coordinates of ligands from a experimental fragment screen and combines the atoms together to produce a novel merged virtual compound, or uses them to predict the bound complex for a provided molecule. …”
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1115
Prediction and validation of anoikis-related genes in neuropathic pain using machine learning.
Published 2025-01-01“…We also used rats to construct an NP model and validated the analyzed hub genes using hematoxylin and eosin (H&E) staining, real-time polymerase chain reaction (PCR), and Western blotting assays.…”
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1116
Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma
Published 2024-12-01“…Univariate Cox regression analysis and Pearson correlation were used to screen for AMD1-related genes (ARGs). Multidimensional bioinformatic algorithms were utilized to establish a risk score model for ARGs. …”
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1117
Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning.
Published 2025-01-01“…Furthermore, we utilized least absolute shrinkage and selection operator (LASSO) regression and Random Forest (RF) algorithms to screen for hub genes. We then validated the expression of these hub genes and constructed nomograms for further validation. …”
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1118
Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis
Published 2025-07-01“…Using logistic regression, SVM, and LASSO regression algorithms, a successful early-diagnosis model for RS was developed, yielding 7 key genes: CNR1, KIT, HTR2A, DES, IL33, UCP2, and PPT1. …”
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1119
Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning
Published 2025-05-01“…Protein-Protein Interaction (PPI) network and machine learning algorithms, including Least Absolute Shrinkage and Selection Operator (LASSO) regression, Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Random Forest (RF), were applied to screen for signature MRDEGs. …”
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1120
High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2...
Published 2024-09-01“…The most common combination of mutations was A2059G (23S rRNA) + S80I (parC), which made up to 33% (18/54) in St. Petersburg and 25.7% (25/97) in Moscow. …”
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