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1401
Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach
Published 2025-07-01“…Machine learning algorithms (Support Vector Machine (SVM), Random Forest (RF) and Least Absolute Shrinkage and Selection Operator (LASSO)) were applied to identify hub genes. …”
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1402
Leveraging Artificial Intelligence and Data Science for Integration of Social Determinants of Health in Emergency Medicine: Scoping Review
Published 2024-10-01“…With a significant focus on the ED and notable NLP model performance, there is an imperative to standardize SDOH data collection, refine algorithms for diverse patient groups, and champion interdisciplinary synergies. …”
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1403
MSGEGA: Multiscale Gaussian Enhancement and Global-Aware Network for Infrared Small Target Detection
Published 2025-01-01“…Specifically, the proposed method demonstrates significant advantages on the screened dataset, achieving an AUC of 0.992. At a detection rate of 0.871, it maintains a false alarm rate of 0.9<italic>e</italic>-5, outperforming all comparison algorithms. …”
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1404
Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis
Published 2024-12-01“…Furthermore, three hub mRNAs (BOC, MLST8, and HMGCS2) from the CeRNA network were screened using LASSO algorithms. GSEA analysis revealed that hub mRNAs were implicated in a great deal of immune system responses and inflammatory pathways, including IL-5 production, MAPK signaling pathway, and JAK-STAT signaling pathway. …”
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1405
A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database
Published 2025-06-01“…Potential risk factors were initially screened applying the eXtreme Gradient Boosting (XGBoost) and Random Forest (RF) machine learning algorithms. …”
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1406
Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation
Published 2025-01-01“…Hub genes were further screened and validated by multiple machine learning (ML) algorithms, followed by a comprehensive visualization of single-cell atlas and immune landscape. …”
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1407
Identification and mechanism analysis of biomarkers related to butyrate metabolism in COVID-19 patients
Published 2025-12-01“…Six machine learning algorithms were employed to determine the best model for identifying biomarkers, and receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic value of the biomarkers in COVID-19. …”
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1408
Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation
Published 2025-03-01“…These discoveries were further validated in subsequent mouse models. An HFHC-induced NASH mouse model was used to validate the therapeutic effects and potential mechanisms of LQAtta on NASH.Results: From the UHPLC-MS/MS analysis of LQAtta, a total of 1518 chemical components were identified, with 106 of them being absorbed into the bloodstream. …”
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1409
Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis
Published 2025-06-01“…Finally, a DVT rat model was established to verify the expression of critical circRNAs and hub genes using real-time quantitative PCR.ResultsA total of 421 circRNAs and 1,082 mRNAs were differentially expressed in DVT. …”
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1410
Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques
Published 2025-03-01“…The utilization of the receiver operating characteristic curve in conjunction with the nomogram model served to authenticate the discriminatory strength and efficacy of the key genes. …”
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1411
Identification of biomarkers associated with inflammatory response in Parkinson's disease by bioinformatics and machine learning.
Published 2025-01-01“…LASSO, SVM-RFE and Random Forest algorithms were used to screen biomarker genes. Then, ROC curves were drawn and PD risk predicting models were constructed on the basis of the biomarker genes. …”
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1412
Identification of subtypes and biomarkers associated with disulfidptosis-related ferroptosis in ulcerative colitis
Published 2025-02-01“…Next, the hub genes were identified by differential analysis and WGCNA algorithms, and three machine learning algorithms were used to screen biomarkers for UC from hub genes. …”
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1413
Identifying potential three key targets gene for septic shock in children using bioinformatics and machine learning methods
Published 2025-06-01“…Three kinds of machine learning models were established, and the candidate genes were screened by intersection to obtain the core genes with diagnostic value. …”
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1414
Crop yield prediction using machine learning: An extensive and systematic literature review
Published 2025-03-01“…Also, the most applied machine learning algorithms are Linear Regression (LR), Random Forest (RF), and Gradient Boosting Trees (GBT) whereas the most applied deep learning algorithms are Convolutional Neural Network (CNN), Long Short-Term Memory (LSTM). …”
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1415
Optimization of Coulomb energies in gigantic configurational spaces of multi-element ionic crystals
Published 2025-07-01“…Coulomb energies of possible configurations generally show a satisfactory correlation to computed energies at higher levels of theory and thus allow to screen for minimum-energy structures. Employing an expansion into a binary optimization problem, we obtain an efficient Coulomb energy optimizer using Monte Carlo and Genetic Algorithms. …”
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1416
Machine learning approaches reveal methylation signatures associated with pediatric acute myeloid leukemia recurrence
Published 2025-05-01“…DNA methylation data from 696 newly diagnosed and 194 relapsed pediatric AML patients were analyzed. Feature selection algorithms, including Boruta, least absolute shrinkage and selection operator, light gradient boosting machine, and Monte Carlo feature selection, were employed to screen and rank methylation sites strongly correlated with AML recurrence. …”
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1417
Identification of metabolic biomarkers in idiopathic pulmonary arterial hypertension using targeted metabolomics and bioinformatics analysis
Published 2024-10-01“…This study used metabolomics, machine learning algorithms and bioinformatics to screen for potential metabolic biomarkers associated with the diagnosis of PAH. …”
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1418
Identification of podocyte molecular markers in diabetic kidney disease via single-cell RNA sequencing and machine learning.
Published 2025-01-01“…Multiple machine-learning algorithms were used to screen and construct diagnostic models to identify hub differentially expressed podocyte marker genes (DE-podos), revealing ARHGEF26 as a significantly downregulated marker in DKD. …”
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1419
Advancements in Herpes Zoster Diagnosis, Treatment, and Management: Systematic Review of Artificial Intelligence Applications
Published 2025-06-01“…Classification tasks (85.2%) dominated AI applications, with neural networks, particularly multilayer perceptron and convolutional neural networks being the most frequently used algorithms. AI applications were analyzed across three domains: (1) diagnosis, where mobile deep neural networks, convolutional neural network ensemble models, and mixed-scale attention-based models have improved diagnostic accuracy and efficiency; (2) treatment, where machine learning models, such as deep autoencoders combined with functional magnetic resonance imaging, electroencephalography, and clinical data, have enhanced treatment outcome predictions; and (3) management, where AI has facilitated case identification, epidemiological research, health care burden assessment, and risk factor exploration for postherpetic neuralgia and other complications. …”
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1420
Intelligent design and synthesis of energy catalytic materials
Published 2025-03-01“…We summarize the sources of data collection, the intelligent algorithms commonly used to build ML models, and the laboratory modules for the intelligent synthesis of materials. …”
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