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Applications of Artificial Intelligence in Drug Repurposing
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422
Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies.
Published 2017-01-01“…This method is referred to as ISIS EM-BLASSO algorithm. Monte Carlo simulation studies validated the new method, which has the highest empirical power in QTN detection and the highest accuracy in QTN effect estimation, and it is the fastest, as compared with efficient mixed-model association (EMMA), smoothly clipped absolute deviation (SCAD), fixed and random model circulating probability unification (FarmCPU), and multi-locus random-SNP-effect mixed linear model (mrMLM). …”
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423
A novel lightweight multi-scale feature fusion segmentation algorithm for real-time cervical lesion screening
Published 2025-02-01“…Therefore, a lightweight algorithm segmentation for cervical lesion real-time screening system is urgently needed. …”
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424
XGBoost Algorithm for Cervical Cancer Risk Prediction: Multi-dimensional Feature Analysis
Published 2025-06-01“…This study is situated at the intersection of clinical oncology and computational intelligence, exploring the potential of gradient-boosting algorithms to overcome the limitations of conventional screening methodologies. …”
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425
Advancements in biomarkers and machine learning for predicting of bronchopulmonary dysplasia and neonatal respiratory distress syndrome in preterm infants
Published 2025-04-01“…For nRDS, biomarkers such as the lecithin/sphingomyelin (L/S) ratio and oxidative stress indicators have been effectively used in innovative diagnostic methods, including attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and high-content screening for ABCA3 modulation. Machine learning algorithms like Partial Least Squares Regression (PLSR) and C5.0 have shown potential in accurately identifying critical health indicators. …”
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426
基于脑影像及临床特征的机器学习模型预测缺血性卒中后心房颤动 A Machine Learning Model Based on Brain Imaging and Clinical Features for Predicting Atrial Fibrillation Detected after Stroke...
Published 2025-04-01“…After retaining independent features, the least absolute shrinkage and selection operator (LASSO) regression algorithm was used for feature selection and to construct a joint prediction model. …”
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427
Cost-effectiveness analysis of MASLD screening using FIB-4 based two-step algorithm in the medical check-up
Published 2025-06-01“…We constructed a hybrid model of the decision tree model and Markov model to compare expected costs and quality-adjusted life-years (QALYs) between ‘screening’ and ‘no screening’ groups from healthcare system perspectives. …”
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428
Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach
Published 2025-01-01“…Intriguingly, 13 key DEGs were identified across hubs and clusters, highlighting their aberrant expressions in cell cycle regulation, immune responses, and cancer pathways. Biomarker screening via Random Forest (RF) model (selected with PyCaret from multiple models) and validation through t-distributed stochastic neighbor embedding (t-SNE) algorithm, principal component analysis (PCA), and ROC curve analysis employing Logistic Regression and Random Forest, identified 6 key DEGs (TXNRD1, CCNB1, BUB1, CDC20, BUB1B, and CCNA2) as promising biomarkers (AUC > 0.7) for clade IIb infection. …”
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Design of public space guide system based on augmented reality technology
Published 2025-07-01“…The research is based on imaging techniques using augmented reality technology and camera image capture. Then, it uses screen error algorithms and scale-invariant feature transformation operators to test the quality of scene spatial models. …”
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431
A Web-Based Interface That Leverages Machine Learning to Assess an Individual’s Vulnerability to Brain Stroke
Published 2025-01-01“…We compare a range of algorithms-including traditional classifiers and deep learning models-and report comprehensive performance metrics (accuracy, precision, recall, F1-score, and AUC-ROC) for each. …”
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432
Exploratory Study on Screening Chronic Renal Failure Based on Fourier Transform Infrared Spectroscopy and a Support Vector Machine Algorithm
Published 2020-01-01“…The samples were input into the SVM after division by the Kennard–Stone (KS) algorithm. Compared with other models, the SVM optimized by a grid search (GS) algorithm performed the best. …”
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433
Empowering Portable Age-Related Macular Degeneration Screening: Evaluation of a Deep Learning Algorithm for a Smartphone Fundus Camera
Published 2024-09-01“…The model was designed to indicate the presence of referable AMD (intermediate and advanced AMD). …”
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434
To Determine the Risk-Based Screening Interval for Diabetic Retinopathy: Development and Validation of Risk Algorithm from a Retrospective Cohort Study
Published 2025-03-01“…Methods The retrospective cohort data from 117,418 subjects who received systematic DR screening in Hong Kong between 2010 and 2016 were included to develop and validate the risk algorithm using a parametric survival model. …”
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Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone
Published 2025-01-01“…Furthermore, highly correlated LCZ types are screened out under the optimal size, the multicollinearity of all LCZ landscape pattern indices is examined and those with multicollinearity are excluded. …”
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436
Suicide Risk Screening in Jails: Protocol for a Pilot Study Leveraging the Mental Health Research Network Algorithm and Health Care Data
Published 2025-06-01“…We hypothesize that a combination of intake screening PAU and the ML model will be the optimal approach, in that the combination will be more accurate and can have practical application in this context. …”
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Study Design and Rationale for the PHINDER Study: Pulmonary Hypertension Screening in Patients with Interstitial Lung Disease for Earlier Detection
Published 2025-07-01“…Planned Outcomes Following study completion, statistical tools will be used to derive a practical model for a screening algorithm using the variables identified in the study as most predictive of PH in patients with ILD. …”
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