The Role of Three Plasma Proteins in the Diagnosis of Ovarian Tumors by Valeria Racheva, Adelaida Ruseva, Svetlana Mateva, Ivan Malkodanski

“…Ovarian cancer is not common, but it is still the fifth leading cause of death from malignant diseases among women worldwide. More than 200,000 women are diagnosed with ovarian cancer each year globally. …”
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Multidimensional Evaluation Framework and Classification Strategy for Low-Carbon Technologies in Office Buildings by Hongjiang Liu, Yuan Song, Yawei Du, Tao Feng, Zhihou Yang

“…The method includes four core components: (1) establishing three archetypal models—low-rise (H ≤ 24 m), mid-rise (24 m < H ≤ 50 m), and high-rise (50 m < H ≤ 100 m) office buildings—based on 99 office buildings in Beijing; (2) classifying 19 key technologies into three clusters—Envelope Structure Optimization, Equipment Efficiency Enhancement, and Renewable Energy Utilization—using bibliometric analysis and policy norm screening; (3) developing a four-dimensional evaluation framework encompassing Carbon Reduction Degree (CRD), Economic Viability Degree (EVD), Technical Applicability Degree (TAD), and Carbon Intensity Degree (CID); and (4) conducting a comprehensive quantitative evaluation using the AHP-entropy-TOPSIS algorithm. …”
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Community-based COVID-19 active case finding and rapid response in the Democratic Republic of the Congo: Improving case detection and response. by John Otokoye Otshudiema, Gervais Léon Tengomo Folefack, Justus M Nsio, Cathy H Kakema, Luigino Minikulu, Aimé Bafuana, Joel B Kosianza, Antoine K Mfumu, Edith Nkwembe, Yannick Munyeku-Bazitama, Sheila Makiala-Mandanda, Noé Guinko, Gisèle Mbuyi, Jean-Marie K Tshilumbu, Guy N Saidi, Moreau-Serge Umba-di-Masiala, Amos K Ebondo, Jean-Jacques Mutonj, Serge Kalombo, Jad Kabeya, Taty K Mawanda, Faustin N Bile, Gaby K Kasereka, Placide Mbala-Kingebeni, Steve Ahuka-Mundeke, Humphrey Cyprian Karamagi, Karl Njuwa Fai, Amédée Prosper Djiguimde

“…This pilot study was modeled on the DRC's National COVID-19 Response Plan and the COVID-19 Ag-RDT screening algorithm defined by the World Health Organization (WHO), with case findings implemented in 259 health areas, 39 health zones, and 9 provinces. …”
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Detecting and Explaining Postpartum Depression in Real-Time with Generative Artificial Intelligence by Silvia García-Méndez, Francisco de Arriba-Pérez

“…Moreover, it addresses the black box problem since the predictions are described to the end users thanks to the combination of LLMS with interpretable ML models (i.e. tree-based algorithms) using feature importance and natural language. …”
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Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma by Can Xu, Jin Yang, Huan Xiong, Xiaoteng Cui, Yuhao Zhang, Mingjun Gao, Lei He, Qiuyue Fang, Changxi Han, Wei Liu, Yangyang Wang, Jin Zhang, Ying Yuan, Zhaomu Zeng, Ruxiang Xu

“…The Lasso, Cox, and Step machine learning algorithms were used to construct and screen the optimal risk assessment prognostic model. …”
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Automated machine learning for predicting perioperative ischemia stroke in endovascularly treated ruptured intracranial aneurysm patients by Yuhang Peng, Ke Bi, Xiaolin Zhang, Ning Huang, Xiang Ji, Weifu Chen, Ying Ma, Yuan Cheng, Yongxiang Jiang, Jianhe Yue

“…The least absolute shrinkage and selection operator (LASSO) method was used to screen essential features associated with PIS. Based on these features, nine machine learning models were constructed using a training set (75% of participants) and assessed on a test set (25% of participants). …”
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Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma. by Xinmei Wang, Kwang Joo Kwak, Zhaogang Yang, Aili Zhang, Xiaoli Zhang, Rachael Sullivan, Dan Lin, Robert L Lee, Carlos Castro, Kalpana Ghoshal, Carl Schmidt, L James Lee

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Integrated single-cell and transcriptome sequencing data reveal the value of IL1RAP in gastric cancer microenvironment and prognosis by Weifeng Yang, Xiaohua Wu, Jian Wang, Wenquan Ou, Xing Huang

“…Immunotherapy prediction models suggested a more favorable response to PD-1 treatment in the low IL1RAP expression group. …”
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Improving synergistic drug combination prediction with signature-based gene expression features in oncology by Mozhgan Mozaffarilegha, Sajjad Gharaghani

“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
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The use of patient-reported outcome measures to improve patient-related outcomes – a systematic review by Joshua M. Bonsel, Ademola J. Itiola, Anouk S. Huberts, Gouke J. Bonsel, Hannah Penton

“…Conclusions The use of PROMs at the individual level has matured considerably. Monitoring/screening applications seem promising particularly for diseases for which treatment algorithms rely on the experienced symptom burden by patients. …”
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Detection of Autism Spectrum Disorder Using A 1-Dimensional Convolutional Neural Network by Aythem Khairi Kareem, Mohammed M. AL-Ani, Ahmed Adil Nafea

“…Results strongly suggest that 1D CNNs have shown improved accuracy in the classification of ASD compared to traditional machine learning algorithms, on all these datasets with higher accuracy of 99.45%, 98.66%, and 90% for Autistic Spectrum Disorder Screening in Data for Adults, Children, and Adolescents respectively as they are better suited for the analysis of time series data commonly used in the diagnosis of this disorder …”
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Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection by Subhajit Ghosh, Sukhen Das Mandal, Subarna Thakur

“…The incidence of non-alcoholic fatty liver disease (NAFLD), encompassing the more severe non-alcoholic steatohepatitis (NASH), is rising alongside the surges in diabetes and obesity. …”
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Estimation of Canopy Chlorophyll Content of Apple Trees Based on UAV Multispectral Remote Sensing Images by Juxia Wang, Yu Zhang, Fei Han, Zhenpeng Shi, Fu Zhao, Fengzi Zhang, Weizheng Pan, Zhiyong Zhang, Qingliang Cui

“…The estimation models for the SPAD values in different growth stages were, respectively, established through five machine learning algorithms: multiple linear regression (MLR), partial least squares regression (PLSR), support vector regression (SVR), random forest (RF) and extreme gradient boosting (XGBoost). …”
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Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study by Stephen Jolles, Ashley Akbari, Andrew Carson-Stevens, Helen Snooks, Alan Watkins, Adrian Edwards, Ann John, Alison Porter, Victoria Williams, Bridie Angela Evans, Ronan Lyons, Bernadette Sewell, Mark Rhys Kingston, Tony Whiffen, Jane Lyons, Rowena Bailey, Catherine A Thornton, Lesley Bethell, Samantha Bufton, Lucy Dixon

“…Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. …”
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Exploring the role of hepsin in prostate cancer: bioinformatics, molecular Docking and molecular dynamics simulations by Hongying Peng, Dan Du, Zhonggui Hu, Zhiliang Xia

“…Although significant advances have been made in early detection, therapeutic strategies for advanced and metastatic PCa remain limited. …”
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Review of applications of deep learning in veterinary diagnostics and animal health by Sam Xiao, Navneet K. Dhand, Zhiyong Wang, Kun Hu, Kun Hu, Peter C. Thomson, John K. House, Mehar S. Khatkar, Mehar S. Khatkar

“…Deep learning (DL), a subfield of artificial intelligence (AI), involves the development of algorithms and models that simulate the problem-solving capabilities of the human mind. …”
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Research trends among new investigators at ISOQOL: a bibliometric analysis from 2019 to 2023 by Jae-Yung Kwon, Manraj N. Kaur, Ellen B. M. Elsman, Ava Mehdipour, Lori Suet Hang Lo, Ahmed M. Y. Osman, Sandrine Herbelet, Carrie-Anne Ng, Lotte van der Weijst, on behalf of the New Investigators Special Interest Group Members

“…Methodology Data on publications authored by 56 NI-SIG members between 2019 and 2023 were extracted from Web of Science and Scopus. A two-step screening process, guided by the Wilson and Cleary model of QoL, identified 561 unique documents for analysis. …”
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ATP6V0A4 as a novel prognostic biomarker and potential therapeutic target in oral squamous cell carcinoma by Xiaopu Gao, Jiamin Zhou, Yu Qiao, Chuyin Lin, Guanxiong Zhang, Qiuyu Wu, Zhikang Su, Qianji Zhang, Songkai Huang

“…Methods This study initially integrated TCGA and GEO databases for cross-platform differential gene screening. A prognostic model was constructed using univariate Cox regression and LASSO regression, complemented by random forest algorithms to identify core genes. …”
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From Molecules to Medicines: The Role of AI-Driven Drug Discovery Against Alzheimer’s Disease and Other Neurological Disorders by Mashael A. Alghamdi

“…Artificial intelligence (AI) tools are of considerable interest in modern drug discovery processes and, by exploiting machine learning (ML) algorithms and deep learning (DL) tools, as well as data analytics, can expedite the identification of new drug targets and potential lead molecules. …”
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Remote Sensing Techniques for Assessing Snow Avalanche Formation Factors and Building Hazard Monitoring Systems by Natalya Denissova, Serik Nurakynov, Olga Petrova, Daniker Chepashev, Gulzhan Daumova, Alena Yelisseyeva

“…The analysis involved screening relevant studies on remote sensing, avalanche dynamics, and data processing techniques. …”
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