HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm. by Mengyao Zhou, Mengfan Xu, Xiangling Zhang, Xiaochun Xing, Yang Li, Guanghui Wang, Guiying Yan

“…Compared to lengthy medical drugs experimental screening, mathematical models and algorithms show great potential in synergistic drug combinations prediction. …”
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Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms by Zakaria Mokadem, Mohamed Djerioui, Bilal Attallah, Youcef Brik

“…This study aims to use computational algorithms to explore the relationship between plasma proteins and AD progression by identifying a panel of plasma proteins that can serve as biomarkers for tracking and diagnosing AD. …”
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Identification and validation of aging related genes in osteoarthritis by Jian Du, Jian Du, Tian Zhou, Yanghui Dong, Yunchao Sun, Wei Peng

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Predicting Superaverage Length of Stay in COPD Patients with Hypercapnic Respiratory Failure Using Machine Learning by Zuo B, Jin L, Sun Z, Hu H, Yin Y, Yang S, Liu Z

“…Ten machine learning algorithms were used to develop and validate a model for predicting superaverage length of stay, and the best model was evaluated and selected.Results: We screened 83 candidate variables using the Boruta algorithm and identified 9 potentially important variables, including: cerebrovascular disease, white blood cell count, hematocrit, D-dimer, activated partial thromboplastin time, fibrin degradation products, partial pressure of carbon dioxide, reduced hemoglobin, and oxyhemoglobin. …”
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Application of Convolutional Neural Network (CNN) Algorithm with ResNet-101 Architecture for Monkey Pox Detection in Human by Al Fathir Rizal Januar, Jamaludin Indra, Dwi Sulistya Kusumaningrum, Sutan Faisal

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Improving routine mental health screening for depression and anxiety in a paediatric lupus clinic: a quality improvement initiative for enhanced mental healthcare by Deborah M Levy, Evelyn Smith, Lawrence Ng, Andrea M Knight, Linda Hiraki, Tala El Tal, Avery Longmore, Audrea Chen, Holly Convery, Dinah Finkelstein, Chetana Kulkarni, Neely Lerman, Karen Leslie, Sharon Lorber, Oscar Mwizerwa, Vandana Rawal, Stephanie Wong, Asha Jeyanathan

“…Statistical process control charts were used to analyse the outcome measure for percentage of screened patients with cSLE. Patient and caregiver satisfaction surveys were conducted at baseline and after screening as a balancing measure.Interventions MH screening workflow with a referral algorithm was developed with stakeholders. …”
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A pulmonary hypertension targeted algorithm to improve referral to right heart catheterization: A machine learning approach by Paola Argiento, Anna D'Agostino, Rossana Castaldo, Monica Franzese, Matteo Mazzola, Ekkehard Grünig, Lavinia Saldamarco, Valeria Valente, Alessandra Schiavo, Erica Maffei, Davide Lepre, Antonio Cittadini, Eduardo Bossone, Michele D'Alto, Luna Gargani, Alberto Maria Marra

“…Conclusions: The PH-targeted ML models could streamline routine screening for PH, facilitating earlier identification and better RHC referrals.…”
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A data-driven machine learning algorithm to predict the effectiveness of inulin intervention against type II diabetes by Shuheng Yang, Ralf Weiskirchen, Wenjing Zheng, Xiangxu Hu, Aibiao Zou, Zhiguo Liu, Hualin Wang

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Integrated Machine Learning Algorithms-Enhanced Predication for Cervical Cancer from Mass Spectrometry-Based Proteomics Data by Da Zhang, Lihong Zhao, Bo Guo, Aihong Guo, Jiangbo Ding, Dongdong Tong, Bingju Wang, Zhangjian Zhou

“…Furthermore, by integrating feature importance values, Shapley values, and local interpretable model-agnostic explanation (LIME) values, we demonstrated that the diagnostic area under the curve (AUC) achieved by our multi-dimensional learning models approached 1, significantly outperforming the diagnostic AUC of single markers derived from the PRIDE database. …”
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Feature Selection based on Genetic Algorithm for Classification of Mammogram Using K-means, k-NN and Euclidean Distance by Kameran Adil Ibrahim

“…., the classifications was done on the bases of the features selected using genetic algorithm. Attempts have also been made to study the performance of each feature selected by Genetic Algorithm (GA) in classification. …”
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Genetics, sex and the use of platelet‐rich plasma influence the development of arthrofibrosis after anterior cruciate ligament reconstruction by Mikel Sánchez, Izarbe Yarza, Cristina Jorquera, Jose María Aznar, Leonor López deDicastillo, Cristina Valente, Renato Andrade, João Espregueira‐Mendes, David Celorrio, Beatriz Aizpurua, Juan Azofra, Diego Delgado

“…Abstract Purpose To identify genes and patient factors that are related to the development of arthrofibrosis in patients after anterior cruciate ligament (ACL) reconstruction and to develop a prognostic model. Methods The study included patients diagnosed with ACL injury who underwent ACL reconstruction. …”
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Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell by I. Yu. Torshin, M. V. Filimonova, O. A. Gromova, L. A. Maiorova, M. A. Sorokina, D. E. Frolova, A. N. Gromov, I. A. Reyer

“…Experimental studies of tumor cell cultures were carried out using the MTT testwith aquacobalamin and HECСA on cell lines of immortalized (telomerized) fibroblasts (Fb-hTERT), lung carcinoma (A549), and breast duct cancer (BT-474).Results. Chemoreactome screening of the effects of molecules on tumor cells made it possible to obtain estimates of cell growth IC50 for 470 tumor cell lines. …”
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Predicting Early-Onset Colorectal Cancer in Individuals Below Screening Age Using Machine Learning and Real-World Data: Case Control Study by Chengkun Sun, Erin Mobley, Michael Quillen, Max Parker, Meghan Daly, Rui Wang, Isabela Visintin, Ziad Awad, Jennifer Fishe, Alexander Parker, Thomas George, Jiang Bian, Jie Xu

“…Given the distinct pathology of colon cancer (CC) and rectal cancer (RC), we created separate prediction models for each cancer type with various ML algorithms. …”
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Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies by Matteo Pappalardo, Federica Maria Sipala, Milena Cristina Nicolosi, Salvatore Guccione, Simone Ronsisvalle

“…The reported techniques include virtual screening, homology modeling, threading, docking, and molecular dynamics. …”
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SARS-CoV-2 Prediction Strategy Based on Classification Algorithms from a Full Blood Examination by C. F. Choukhan, I. Lasri, R. El Hatimi, M. R. Lemnaouar, M. Esghir

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Economic evaluation of a novel genetic screening test for risk of venous thromboembolism compared with standard of care in women considering combined hormonal contraception in Swit... by Zanfina Ademi, C Simone Sutherland, Matthias Schwenkglenks, Nadine Schur, Joëlle Michaud, Myriam Lingg, Arjun Bhadhuri, Thierry D. Pache, Johannes Bitzer, Pierre Suchon, Valerie Albert, Kurt E. Hersberger, Goranka Tanackovic

“…The risk of having a VTE was derived from the risk algorithm that underpins the PP test. The remaining model inputs relating to population characteristics, costs, health resource use, mortality and utilities were derived from published studies or national sources. …”
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Improving Systematic Review Updates With Natural Language Processing Through Abstract Component Classification and Selection: Algorithm Development and Validation by Tatsuki Hasegawa, Hayato Kizaki, Keisho Ikegami, Shungo Imai, Yuki Yanagisawa, Shuntaro Yada, Eiji Aramaki, Satoko Hori

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Personalised Prostate Cancer Diagnosis: Evaluating Biomarker-based Approaches to Reduce Unnecessary Magnetic Resonance Imaging and Biopsy Procedures by Timo F.W. Soeterik, Xiaobo Wu, Roderick C.N. Van den Bergh, Claudia Kesch, Fabio Zattoni, Ugo Falagario, Alberto Martini, Marcin Miszczyk, Vittorio Fasulo, Martina Maggi, Veeru Kasivisvanathan, Pawel Rajwa, Giancarlo Marra, Giorgio Gandaglia, Peter K.F. Chiu

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Driver injury severity in two-vehicle accidents considering collision role by JIN Wenzhou, PEI Xiaohang, TANG Zuogan, YAO Yinjie

“…In order to study the influencing factors of driver injury severity and the interaction effects of collision roles in two-vehicle accidents, based on the data of two-vehicle collision accidents in Shenzhen from 2018 to 2020, we calculate the value of importance degree of characteristic variables by using random forest algorithm to screen out the candidate independent variables, and establish a binary logit model of driver injury severity considering collision angle. …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…Although more data were available to populate the screening population model, there was substantial uncertainty across all models. …”
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