Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation by Yoonsung Kwon, Asta Blazyte, Yeonsu Jeon, Yeo Jin Kim, Kyungwhan An, Sungwon Jeon, Hyojung Ryu, Dong-Hyun Shin, Jihye Ahn, Hyojin Um, Younghui Kang, Hyebin Bak, Byoung-Chul Kim, Semin Lee, Hyung-Tae Jung, Eun-Seok Shin, Jong Bhak

“…Subsequent validation of identified biomarkers employed an artificial intelligence-based risk prediction models: a linear calculation-based methylation risk score model and two tree-based machine learning models: Random Forest and XGBoost. …”
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Ekyeyo Mobile Application by Nkuba, Blair, Kansiime, Daniel

“…The app incorporates advanced search algorithms, tailored job recommendations, and streamlined candidate screening to improve job-matching accuracy. …”
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Opportunities and Challenges of Cardiovascular Disease Risk Prediction for Primary Prevention Using Machine Learning and Electronic Health Records: A Systematic Review by Tianyi Liu, Andrew J. Krentz, Zhiqiang Huo, Vasa Ćurčin

“…The synthesis underscores the superiority of ML in modeling intricate EHR-derived risk factors, facilitating precision-driven cardiovascular risk assessment. …”
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Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer by Mengdi Zhu, Jinna Lin, Haohan Liu, Jingru Wang, Nianqiu Liu, Yudong Li, Hongna Lai, Qianfeng Shi

“…Using Consensus Cluster Plus and the LASSO risk model, we screened 6 acetylation-related genes (KAT2B, TAF1L, CDC37, CCDC107, C17orf106, and ASPSCR1) and constructed a 6-gene risk model of luminal breast cancer. …”
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Investigating the Complexity of Multidimensional Symptom Experiences in Patients With Cancer: Systematic Review of the Network Analysis Approach by Vincent Richard, Allison Gilbert, Emanuela Pizzolla, Giovanni Briganti

“…Several NA approaches were used: network visualization (n=1), Bayesian network (n=1), pairwise Markov random field and IsingFit method (n=1), unregularized Gaussian graphical model (n=2), regularized partial correlation network (n=6), network visualization and community NA (n=1), network visualization and Walktrap algorithm (n=1), undirected network model with the Fruchterman-Reingold and edge-betweenness approaches (n=4), biased correlation and concise pattern diagram (n=1), extended Bayesian information criterion graphical LASSO method (n=3), cross-lagged panel network (n=1), and unspecified NA (n=3). …”
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TMSB4X is a regulator of inflammation-associated ferroptosis, and promotes the proliferation, migration and invasion of hepatocellular carcinoma cells by Linlin Tang, Yangli Jin, Jinxu Wang, Xiuyan Lu, Mengque Xu, Mingwei Xiang

“…Results 157 genes related to inflammation and ferroptosis in HCC were obtained by WGCNA. rLasso algorithm, with the highest C-index, screened out 29 hub genes, and this model showed good efficacy to predict the prognosis of HCC patients. …”
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Iterative phase contrast CT reconstruction with novel tomographic operator and data-driven prior. by Stefano van Gogh, Subhadip Mukherjee, Jinqiu Xu, Zhentian Wang, Michał Rawlik, Zsuzsanna Varga, Rima Alaifari, Carola-Bibiane Schönlieb, Marco Stampanoni

“…Moreover, the highly ill-conditioned differential nature of the GI-CT forward operator renders the inversion from corrupted data even more cumbersome. In this paper, we propose a novel regularized iterative reconstruction algorithm with an improved tomographic operator and a powerful data-driven regularizer to tackle this challenging inverse problem. …”
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Integrating status-neutral and targeted HIV testing in Zimbabwe: A complementary strategy. by Hamufare D Mugauri, Owen Mugurungi, Joconiah Chirenda, Kudakwashe Takarinda, Prosper Mangwiro, Mufuta Tshimanga

“…First tests were 65% more likely to test HIV positive (a95%CI: 1.43, 1.91) whilst screened patients were 3.89 times more likely to link to HIV prevention services (a95%CI: 3.05, 4.97), against 25.5% (n = 1,871) linkage among patients not screened.…”
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Novel insights of disulfidptosis-mediated immune microenvironment regulation in atherosclerosis based on bioinformatics analyses by Huanyi Zhao, Zheng Jin, Junlong Li, Junfeng Fang, Wei Wu, J. F. Fang

“…In addition, we established a foam cell model in vitro and an AS mouse model in vivo to verify the expressions of hub genes. …”
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Cadmium Exposure Disrupts Uterine Energy Metabolism and Coagulation Homeostasis During Labor in Institute of Cancer Research Mice: Insights from Transcriptomic Analysis by Yueyang Wang, Yichen Bai, Yi Wang, Yan Cai

“…This study is the first to establish a model of Cd exposure in the uterus of laboring mice and investigate the underlying metabolic mechanisms through transcriptomic analysis. …”
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Evaluation of three commercial rapid immunoassays for the diagnosis of Clostridioides difficile infection by Hannes Bjarki Vigfússon, Theresa Ennefors, Torbjörn Norén, Martin Sundqvist

“…The C. diff Quik Chek Complete performed the best of the three immunoassays, and when used in combination with NAAT, is a viable option for the laboratory diagnosis of CDI.IMPORTANCELaboratory diagnosis of Clostridioides difficile infection is complex, and current guidelines recommend a two-step diagnostic algorithm with a sensitive screening test and a more specific confirmatory test. …”
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Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. by Patrick Y Sips, Xu Shi, Gabriel Musso, Anjali K Nath, Yanbin Zhao, Jason Nielson, Jordan Morningstar, Amy E Kelly, Brittney Mikell, Eva Buys, Vikhyat Bebarta, Jared Rutter, V Jo Davisson, Sari Mahon, Matthew Brenner, Gerry R Boss, Randall T Peterson, Robert E Gerszten, Calum A MacRae

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Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning by Shuxian Pan, Zibing Wang

“…Predictive models were constructed using three machine learning algorithms to analyze and statistically evaluate clinical characteristics, including immune cell data. …”
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Smart driving assistance system for mining operations in foggy environments by Swades Kumar Chaulya, Monika Choudhary, Naresh Kumar, Vikash Kumar, Abhishek Chowdhury

“…In image processing under dense fog where visibility is below 5 m, typical performance standards are around 0.9 for contrast, above 0.5 for structural similarity index measure, over 20 dB for peak signal-to-noise ratio, over 0.5 for visual information fidelity, and more than 0.5 for universal quality index. Thus, the test results indicate that the proposed image enhancement algorithm produced significantly improved images, proving its effectiveness in extremely low visibility situations. …”
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Plasma metabolite biomarker identification study for the early detection of gastric cancer by Juan Zhu, Yida Huang, Bin Liu, Xue Li, Li Yuan, Le Wang, Kun Qian, Yingying Mao, Lingbin Du, Xiangdong Cheng

“…Ultra-performance liquid chromatography–mass spectrometry–based metabolomics methods were used to characterize the subjects’ plasma metabolic profiles and to screen and validate the GC biomarkers. Five machine learning algorithms (neural network, support vector machine, ridge regression, lasso regression and Naïve Bayes) were used to build a diagnostic model. …”
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Multi-Dimensional Lithology Identification Method Based on Microresistivity Image Logging by LIU Juan, MIN Xuanlin, QI Zhongli, YI Jun, LAI Fuqiang, ZHOU Wei

“…For the electrical imaging color features of different resistivity responses (mudstone, calcareous mudstone and sandy mudstone), K-means++ algorithm is used to screen out the clustering centers of the overall distribution of the data set to achieve fast classification of the electro-imaging colors. …”
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The use of heart rate variability, oxygen saturation, and anthropometric data with machine learning to predict the presence and severity of obstructive sleep apnea by Rafael Rodrigues dos Santos, Matheo Bellini Marumo, Alan Luiz Eckeli, Helio Cesar Salgado, Luiz Eduardo Virgílio Silva, Renato Tinós, Rubens Fazan

“…IntroductionObstructive sleep apnea (OSA) is a prevalent sleep disorder with a high rate of undiagnosed patients, primarily due to the complexity of its diagnosis made by polysomnography (PSG). Considering the severe comorbidities associated with OSA, especially in the cardiovascular system, the development of early screening tools for this disease is imperative. …”
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Progress and challenges of artificial intelligence in lung cancer clinical translation by Erjia Zhu, Amgad Muneer, Jianjun Zhang, Yang Xia, Xiaomeng Li, Caicun Zhou, John V. Heymach, Jia Wu, Xiuning Le

“…Abstract Artificial intelligence (AI) algorithms, such as convolutional neural networks and transformers, have significantly impacted cancer care. …”
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Fundus camera-based precision monitoring of blood vitamin A level for Wagyu cattle using deep learning by Nanding Li, Naoshi Kondo, Yuichi Ogawa, Keiichiro Shiraga, Mizuki Shibasaki, Daniele Pinna, Moriyuki Fukushima, Shinichi Nagaoka, Tateshi Fujiura, Xuehong De, Tetsuhito Suzuki

“…This study developed a handheld camera system capable of capturing cattle fundus images and predicting vitamin A levels in real time using deep learning. 4000 fundus images from 50 Japanese Black cattle were used to train and test the prediction algorithms, and the model achieved an average 87%, 83%, and 80% accuracy for three levels of vitamin A deficiency classification (particularly 87% for severe level), demonstrating the effectiveness of camera system in vitamin A deficiency prediction, especially for screening and early warning. …”
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Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications by Can Qi, Can Qi, Ziwei Zhao, Lin Chen, Le Wang, Yun Zhou, Guochen Duan, Guochen Duan

“…A total of five biomarkers,[Selenoprotein P1 (SEPP1), Fibrinogen-like protein 2 (FGL2), NK cell lectin-like receptor K1 (KLRK1), ATP-binding cassette transporters 6(ABCA6) and Galectins(GAL)], were screened, and a risk model based on the biomarkers was created. …”
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