Leveraging automated time-lapse microscopy coupled with deep learning to automate colony forming assay by Anusha Klett, Anusha Klett, Dennis Raith, Dennis Raith, Paula Silvestrini, Paula Silvestrini, Paula Silvestrini, Matías Stingl, Jonas Bermeitinger, Avani Sapre, Avani Sapre, Avani Sapre, Martin Condor, Roman Melachrinos, Mira Kusterer, Alexandra Brand, Guido Pisani, Guido Pisani, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Marie Follo, Marie Follo, Jesús Duque-Afonso, Roland Mertelsmann, Roland Mertelsmann

“…Brightfield images were used to train a YOLOv8 object detection network, achieving a mAP50 score of 86% for identifying single cells, clusters, and colonies, and 97% accuracy for Z-stack colony identification with a multi-object tracking algorithm. The detection model accurately identified the majority of objects in the dataset.ResultsThis AI-assisted CFA was successfully applied for density optimization, enabling the determination of seeding densities that maximize plating efficiency (PE), and for IC50 determination, offering an efficient, less labor-intensive method for testing drug concentrations. …”
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Acoustic-based machine learning approaches for depression detection in Chinese university students by Yange Wei, Yange Wei, Shisen Qin, Fengyi Liu, Rongxun Liu, Yunze Zhou, Yuanle Chen, Xingliang Xiong, Wei Zheng, Guangjun Ji, Yong Meng, Fei Wang, Fei Wang, Ruiling Zhang

“…Among five machine learning algorithms, LDA model demonstrated the highest classification performance, with an AUC of 0.771. …”
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Leveraging diverse cell-death patterns in diagnosis of sepsis by integrating bioinformatics and machine learning by Mi Liu, Xingxing Gao, Hongfa Wang, Yiping Zhang, Xiaojun Li, Renlai Zhu, Yunru Sheng

“…The machine learning algorithm screened three PCD-related genes, NLRC4, TXN and S100A9, as potential biomarkers for sepsis. …”
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Machine learning-based ultrasound radiomics for predicting risk of recurrence in breast cancer by Wei Fan, Hao Cui, Xiaoxue Liu, Xudong Zhang, Xinran Fang, Junjia Wang, Zihao Qin, Xiuhua Yang, Jiawei Tian, Lei Zhang

“…The receiver operating characteristic (ROC), calibration, and decision curve analysis (DCA) curves were used to evaluate the model’s clinical applicability and predictive performance.ResultsA total of 12 ultrasound radiomics features were screened, of which wavelet.LHL first order Mean features weighed more and tended to have a high risk of recurrence. …”
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A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data by Fengchun Ren, Xiao Zhao, Qin Yang, Huaqiang Liao, Yudong Zhang, Xuemei Liu

“…Ultimately, a user-friendly webserver was deployed for the predictive model and is freely accessed at http://bio-medical.online/admxp/.DiscussionThe associated webserver enables accessible risk screening and underpins precision prevention strategies in aging populations.…”
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Empowering Healthcare: TinyML for Precise Lung Disease Classification by Youssef Abadade, Nabil Benamar, Miloud Bagaa, Habiba Chaoui

“…These findings highlight the potential of TinyML to provide accessible, reliable, and real-time diagnostic tools, particularly in remote and underserved areas, demonstrating the transformative impact of integrating advanced AI algorithms into portable medical devices. This advancement facilitates the prospect of automated respiratory health screening using lung sounds.…”
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Optimized Allocation of Flood Control Emergency Materials Based on Loss Quantification by Wei Wang, Yunqing Wang, Li Huang, Yue Song

“…The center of gravity method is used to address demand when constructing the quantitative function of out‐of‐stock loss. The NSGA‐II algorithm was selected to generate the results after the method comparison to ultimately determine the Pareto solution of the model. …”
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Optimizing the dynamic treatment regime of outpatient rehabilitation in patients with knee osteoarthritis using reinforcement learning by Sijia Liu, Jiawei Luo, Chengqi He

“…Then, based on the key features screened out, a dynamic treatment recommendation system was constructed by using deep reinforcement learning algorithms, including Deep Deterministic Policy Gradien(DDPG), Deep Q-Network(DQN) and Batch-Constrained Q-learning(BCQ). …”
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Mitochondrial-Localized Protein Transcript Abundance can Predict the Prognosis of Endometrial Carcinoma: A Retrospective Analysis by Weifei Liang, Hong Lin, Donglin Sun, Minghui Tang

“…Moreover, a nomogram was constructed through the combination of the scoring algorithm and the patient’s clinical features. Conclusions: The scoring algorithm based on mitochondrial gene expression can assist clinicians in predicting the postoperative survival rate of patients, allowing them to devise more precise treatment programs.…”
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Evaluation of machine learning methods for prediction of heart failure mortality and readmission: meta-analysis by Hamed Hajishah, Danial Kazemi, Ehsan Safaee, Mohammad Javad Amini, Maral Peisepar, Mohammad Mahdi Tanhapour, Arian Tavasol

“…In total, 346 machine learning models were evaluated, with the most common algorithms being random forest, logistic regression, and gradient boosting. …”
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Implementation costs and cost-effectiveness of ultraportable chest X-ray with artificial intelligence in active case finding for tuberculosis in Nigeria. by Tushar Garg, Stephen John, Suraj Abdulkarim, Adamu D Ahmed, Beatrice Kirubi, Md Toufiq Rahman, Emperor Ubochioma, Jacob Creswell

“…We provide implementation cost and cost-effectiveness estimates of different screening algorithms using symptoms, CXR and AI in Nigeria. …”
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Identification and Evaluation of Lipocalin-2 in Sepsis-Associated Encephalopathy via Machine Learning Approaches by Hu J, Chen Z, Wang J, Xu A, Sun J, Xiao W, Yang M

“…Subsequently, neuroinflammation-related genes were obtained to construct a neuroinflammation-related signature. The AddModuleScore algorithm was used to calculate neuroinflammation scores for each cell subpopulation, whereas the CellCall algorithm was used to assess the crosstalk between neutrophils and other cell subpopulations. …”
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Machine Learning and Interpretability Study for Predicting 30-Day Unplanned Readmission Risk of Schizophrenia: A Retrospective Study by Tan Y, Chen G, Wang S, Zhan X, Cheng R, Qiao L, Zhang Z, Liu Y

“…Models were constructed after screening variables using the multiple linear regression and feature importance methods. …”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…A high IoU value in medical imaging analysis reflects the model’s ability to accurately delineate object boundaries.ConclusionDeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. …”
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Prevention of Cardiometabolic Syndrome in Children and Adolescents Using Machine Learning and Noninvasive Factors: The CASPIAN-V Study by Hamid Reza Marateb, Mahsa Mansourian, Amirhossein Koochekian, Mehdi Shirzadi, Shadi Zamani, Marjan Mansourian, Miquel Angel Mañanas, Roya Kelishadi

“…We applied the XGBoost algorithm to analyze key noninvasive variables, including self-rated health, sunlight exposure, screen time, consanguinity, healthy and unhealthy dietary habits, discretionary salt and sugar consumption, birthweight, and birth order, father and mother education, oral hygiene behavior, and family history of dyslipidemia, obesity, hypertension, and diabetes using five-fold cross-validation. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. …”
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Retinal Microvascular Characteristics—Novel Risk Stratification in Cardiovascular Diseases by Alexandra Cristina Rusu, Klara Brînzaniuc, Grigore Tinica, Clément Germanese, Simona Irina Damian, Sofia Mihaela David, Raluca Ozana Chistol

“…This study aims to identify the retinal microvascular features associated with CHDs and evaluate their potential use in a CHD screening algorithm in conjunction with traditional risk factors. …”
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Effectiveness of mindfulness-based therapy, stress reduction in hypertension and prehypertension: a systematic review by D. I. Nozdrachev, M. N. Solovieva, K. A. Zamyatin

“…The systematic review was prepared according to the PRISMA algorithm with minor modifications. The search algorithm included articles in Russian and English, indexed in the Pubmed/MEDLINE and Cochrane Library databases. …”
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Sialyltransferase-related genes as predictive factors for therapeutic response and prognosis in cervical cancer by Jia Shao, Can Zhang, Yaonan Tang, Aiqin He, Xiangyan Cheng

“…Cox regression analysis and “glmnet” R package were applied to establish the relevant risk model. “MCPcounter” R package, ESTIMATE algorithm and TIMER online tools were used to depict the tumor immune microenvironment in CC. …”
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Fetal electrocardiography and artificial intelligence for prenatal detection of congenital heart disease by Ivar R. deVries, Judith O. E. H. vanLaar, Marieke B. van der Hout‐van der Jagt, Sally‐Ann B. Clur, Rik Vullings

“…More research is required to improve performance and determine the benefits to clinical practice.…”
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