Glypican-3 regulated epithelial mesenchymal transformation-related genes in osteosarcoma: based on comprehensive tumor microenvironment profiling by Jiaming Zhang, Wei Wang

“…The least absolute shrinkage and selection operator (LASSO) algorithm was applied to screen candidate genes for developing a prognostic model. …”
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Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

“…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. Machine learning algorithms were used to screen for the hub RA-RF differential expression genes, and then a Logistic Regression (LR) model was constructed. …”
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Development of a machine learning prognostic model for early prediction of scrub typhus progression at hospital admission based on clinical and laboratory features by Youguang Lu, Zixu Wang, Junhu Wang, Yingqing Mao, Chuanshen Jiang, Jinpiao Wu, Haizhou Liu, Haiming Yi, Chao Chen, Wei Guo, Liguan Liu, Yong Qi

“…Eighteen objective clinical and laboratory features collected at admission were screened using various feature selection algorithms, and used to construct models based on six machine learning algorithms.Results The model based on Gradient Boosting Decision Tree using 14 features screened by Recursive Feature Elimination was evaluated as the optimal one. …”
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Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research by Fan Jiang, Fan Jiang, Fan Jiang, Yanhua Liu, Linsheng Li, Linsheng Li, Ruizi Ni, Ruizi Ni, Yajing An, Yajing An, Yufeng Li, Yufeng Li, Lingxia Zhang, Wenping Gong

“…A Naive Bayes (NB) model incorporating these two markers demonstrated robust diagnostic performance: training set AUC: median = 0.8572 (inter-quartile range 0.8002, 0.8708), validation AUC = 0.5719 (0.51645, 0.7078), and subgroup AUC = 0.8635 (0.8212, 0.8946).ConclusionOur multicohort analysis established an NB-based diagnostic model utilizing S100A12/S100A8, which maintains diagnostic accuracy across diverse geographic, ethnic, and clinical variables (including HIV co-infection), highlighting its potential for clinical translation in LTBI/ATB differentiation.…”
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AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen by Zhen Gao, Qiyuan Bai, Mingyu Wei, Hao Chen, Yan Yan, Jiahao Mao, Xiangzhi Kong, Yang Yu

“…Conclusions: Using machine-learning algorithms, we built a prediction model of a treatment plan for patients with concomitant DM and CHD by integrating patients' information and screened the best feature set containing 15 features, which provides help and strategies to develop the best treatment plan for patients with concomitant DM and CHD.…”
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Low-cost and scalable machine learning model for identifying children and adolescents with poor oral health using survey data: An empirical study in Portugal. by Susana Lavado, Eduardo Costa, Niclas F Sturm, Johannes S Tafferner, Octávio Rodrigues, Pedro Pita Barros, Leid Zejnilovic

“…Such a model could enable scalable and cost-effective screening and targeted interventions, optimizing limited resources to improve oral health outcomes. …”
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A novel prediction model for the prognosis of non-small cell lung cancer with clinical routine laboratory indicators: a machine learning approach by Yuli Wang, Na Mei, Ziyi Zhou, Yuan Fang, Jiacheng Lin, Fanchen Zhao, Zhihong Fang, Yan Li

“…Finally, critical variables in the optimal model were screened based on the interpretable algorithms to build a decision tree to facilitate clinical application. …”
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The Automatable Activity–Based Approach to Complexity Unit Scoring as a task-specific model approach to monetizing outcomes of pathology artificial intelligence solutions by Stavros Pantelakos, Martha Nifora, Georgios Agrogiannis

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An efficient hybrid Hopfield convolutional neural network for detecting spam bots in Twitter platform by A.V. Santhosh Kumar, N. Suresh Kumar, R. Kanniga Devi

“…The extracted features are then subjected to feature selection, where a meta-heuristic-based optimization algorithm called the Binary Golden Search Optimization algorithm (BGSO) is used. …”
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Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity by Shan Jin, Junbin Yin, Wei Li, Ni Mao

“…Multiple machine learning algorithms were applied to screen and verify the diagnostic genes of intersection genes. …”
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Development and validation of an early predictive model for hemiplegic shoulder pain: a comparative study of logistic regression, support vector machine, and random forest by Qiang Wu, Qiang Wu, Fang Zhang, Yuchang Fei, Zhenfen Sima, Shanshan Gong, Qifeng Tong, Qingchuan Jiao, Hao Wu, Jianqiu Gong, Jianqiu Gong

“…ObjectiveIn this study, we aim to identify the predictive variables for hemiplegic shoulder pain (HSP) through machine learning algorithms, select the optimal model and predict the occurrence of HSP.MethodsData of 332 stroke patients admitted to a tertiary hospital in Zhejiang Province from January 2022 to January 2023 were collected. …”
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Machine Learning-Assisted NIR Spectroscopy for Dynamic Monitoring of Leaf Potassium in Korla Fragrant Pear by Mingyang Yu, Weifan Fan, Junkai Zeng, Yang Li, Lanfei Wang, Hao Wang, Feng Han, Jianping Bao

“…By measuring leaf potassium content at the fruit setting, expansion, and maturity stages (decreasing from 1.60% at fruit setting to 1.14% at maturity), this study reveals its dynamic change pattern and establishes a high-precision prediction model by combining near-infrared spectroscopy (NIRS) with machine learning algorithms. …”
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Comparative analysis of machine learning models for malaria detection using validated synthetic data: a cost-sensitive approach with clinical domain knowledge integration by Gudi V. Chandra Sekhar, Chekol Alemu

“…Machine learning offers promising solutions for automated detection, but systematic algorithm comparison using clinically validated data remains limited. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…A discriminative diagnostic model was developed using a multivariate logistic regression algorithm. …”
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Plasma proteomics-based risk scores for psoriasis prediction: a novel approach to early diagnosis by Siyu Wei, Zehong Yue, Chen Sun, Yuping Zou, Haiyan Chen, Junxian Tao, Jing Xu, Yuan Xu, Ning Wang, Yan Guo, Qinduo Ren, Chang Wang, Songlin Lu, Ye Ma, Yu Dong, Chen Zhang, Hongmei Sun, Guoping Tang, Fanwu Kong, Wenhua Lv, Zhenwei Shang, Mingming Zhang, Yongshuai Jiang, Hongchao Lyu

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Molecular characterization and prognostic modeling associated with M2-like tumor-associated macrophages in breast cancer: revealing the immunosuppressive role of DLG3 by Ziqiang Wang, Jing Zhang, Huili Chen, Xinyu Zhang, Kai Zhang, Feiyue Zhang, Yiluo Xie, Hongyu Ma, Linfeng Pan, Qiang Zhang, Min Lu, Hongtao Wang, Chaoqun Lian

“…Consensus clustering analysis identified three molecular subtypes with distinct clinical features, and we explored potential differences in genomic mutations, pathway enrichment, and immune infiltration in patients between subtypes. Machine learning algorithms were used to screen key genes and construct M2-like macrophage-associated prognostic models. …”
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Construction of an oligometastatic prediction model for nasopharyngeal carcinoma patients based on pathomics features and dynamic multi-swarm particle swarm optimization support ve... by Yunfei Li, Dongni Zhang, Yiren Wang, Yiren Wang, Yiheng Hu, Zhongjian Wen, Zhongjian Wen, Cheng Yang, Ping Zhou, Wen-Hui Cheng

“…A demo of the DMS-PSO-SVM modeling algorithm code used in this study can be found on Github (https://github.com/Edward-E-S-Wang/DMS-PSO-SVM).…”
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The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma by Fuqing Chen, Yifan Cai, Xiangmei Chen, Changzhou Chen, Qinliang Fang, Jianming Liu, Yibin Zhang, Jianyin Zhou

“…SVM algorithm was used to classify HCC patients based on HSCRGs. …”
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Development of an MRI based artificial intelligence model for the identification of underlying atrial fibrillation after ischemic stroke: a multicenter proof-of-concept analysisRes... by Zijie Zhang, Yang Ding, Kaibin Lin, Wenli Ban, Luyue Ding, Yudong Sun, Chuanliang Fu, Yihang Ren, Can Han, Xue Zhang, Xiaoer Wei, Shundong Hu, Yuwu Zhao, Li Cao, Jun Wang, Saman Nazarian, Ying Cao, Lan Zheng, Min Zhang, Jianliang Fu, Jingbo Li, Xiang Han, Dahong Qian, Dong Huang

“…More importantly, our proposed model identified all the AF patients that were diagnosed with Holter monitoring during index stroke admission. …”
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Non-Invasive Detection of Breast Cancer by Low-Coverage Whole-Genome Sequencing from Plasma by Li Peng, Ru Yao, Sihang Gao, Yang Qu, Li Qu, Jingbo Zhang, Yidong Zhou

“…Our approach adopted principal component analysis and a generalized linear model algorithm to distinguish between breast cancer and normal samples. …”
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