Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma by Duo Wang, Duo Wang, Duo Wang, Jihao Tu, Jihao Tu, Jianfeng Liu, Jianfeng Liu, Yuting Piao, Yuting Piao, Yiming Zhao, Yiming Zhao, Ying Xiong, Ying Xiong, Jianing Wang, Jianing Wang, Xiaotian Zheng, Xiaotian Zheng, Bin Liu, Bin Liu

“…We developed a novel machine learning framework that incorporated 12 machine learning algorithms and their 127 combinations to construct a consensus GPRS to screen biomarkers with diagnostic significance and clinical translation, which was assessed by the internal and external validation datasets. …”
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RNA m7G methylation regulators and targets significantly contribute to chronic obstructive pulmonary disease by Chenyu Zhu, Luyi Tan, Xinyu Zhang, Wenli Cheng, Min Li, Yibo Chen, Wenjuan Zhang

“…In this study, the combined roles of m7G methylation regulators were explored in COPD for the first time by integrated bioinformatic methods. The machine algorithms screened 7 disease signature genes relevant to clinical indicators, including CYFIP2, EIF3D, EIF4G3, GEMIN5, METTL1, SNUPN and NCBP2, and METTL1 was related to the progression in COPD. …”
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Ambulatory Oxygen for Pulmonary Fibrosis (OxyPuF): a randomised controlled trial and acceptability study by Rachel L Adams, Alisha Maher, Nicola Gale, Anjali Crawshaw, David Thickett, Alice M Turner

“…Traditional qualitative analysis and arts-based coproduction analysis approaches were used to produce a short film. An economic model was planned but could not occur due to early termination. …”
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GLUcose COntrol Safety & Efficacy in type 2 DIabetes, a systematic review and NETwork meta-analysis. by Guillaume Grenet, Shams Ribault, Giao Bao Nguyen, Faustine Glais, Augustin Metge, Thomas Linet, Behrouz Kassai-Koupai, Catherine Cornu, Théodora Bejan-Angoulvant, Sylvie Erpeldinger, Rémy Boussageon, Aurore Gouraud, Fabrice Bonnet, Michel Cucherat, Philippe Moulin, François Gueyffier

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In the Refractory Hypertension “Labyrinth”. Focus on Primary Hyperaldosteronism by O. V. Tsygankova, T. I. Batluk, L. D. Latyntseva, E. V. Akhmerova, N. M. Akhmedzhanov

“…It should not only have made the diagnosis easy, but it could have also absolutely justified the surgical tactics. …”
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Machine learning in dentistry and oral surgery: charting the course with bibliometric insights by Shuangwei Liu, Yuquan Hao, Shijie Zhu, Liyao Wan, Zhe Yi, Zhichang Zhang

“…Moreover, challenges, such as data availability and security, algorithmic biases, and “black-box models”, must be addressed. …”
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Artificial intelligence technology in ophthalmology public health: current applications and future directions by ShuYuan Chen, Wen Bai, Wen Bai

“…Key issues include interoperability with electronic health records (EHR), data security and privacy, data quality and bias, algorithm transparency, and ethical and regulatory frameworks. …”
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AI-driven biomarker discovery: enhancing precision in cancer diagnosis and prognosis by Esther Ugo Alum

“…Existing gaps include data quality, algorithmic transparency, and ethical concerns around privacy, among others. …”
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Advancements in Machine Learning (ML): Transforming the Future of Blood Cancer Detection and Outcome Prediction by Wiebke Rösler, Michael Roiss, Corinne Widmer

“…The diagnosis and treatment of hematologic malignancies are becoming more and more complex. Growing knowledge of pathophysiology, diagnostic methods and, last but not least, treatment options offer many opportunities for patients, but integrating the growing amount of knowledge into daily practice can be challenging. …”
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Advancements in the application of artificial intelligence in the field of colorectal cancer by Mengying Zhu, Mengying Zhu, Zhenzhu Zhai, Yue Wang, Fang Chen, Ruibin Liu, Ruibin Liu, Xiaoquan Yang, Guohua Zhao

“…In this context, artificial intelligence (AI) has shown immense potential in revolutionizing CRC management, serving as one of the most effective screening tools. AI, utilizing machine learning (ML) and deep learning (DL) algorithms, improves early detection, diagnosis, and treatment by processing large volumes of medical data, uncovering hidden patterns, and forecasting disease development. …”
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Identifying Data-Driven Clinical Subgroups for Cervical Cancer Prevention With Machine Learning: Population-Based, External, and Diagnostic Validation Study by Zhen Lu, Binhua Dong, Hongning Cai, Tian Tian, Junfeng Wang, Leiwen Fu, Bingyi Wang, Weijie Zhang, Shaomei Lin, Xunyuan Tuo, Juntao Wang, Tianjie Yang, Xinxin Huang, Zheng Zheng, Huifeng Xue, Shuxia Xu, Siyang Liu, Pengming Sun, Huachun Zou

“…We trained a supervised machine learning model and developed pathways to classify individuals before evaluating its diagnostic validity and usability on an external cohort. …”
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Bioinformatics analysis of ferroptosis-related biomarkers and potential drug predictions in doxorubicin-induced cardiotoxicity by Jian Yu, Jian Yu, Jiangtao Wang, Xinya Liu, Xinya Liu, Cancan Wang, Cancan Wang, Li Wu, Yuanming Zhang, Yuanming Zhang

“…Utilized LASSO regression, SVM-RFE, and RF algorithms to identify key genes, followed by validation using external datasets (GSE232331, GSE230638) and ROC curve plotting to determine the diagnostic value of key genes. …”
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Estimation of potato leaf area index based on spectral information and Haralick textures from UAV hyperspectral images by Jiejie Fan, Jiejie Fan, Yang Liu, Yang Liu, Yiguang Fan, Yihan Yao, Riqiang Chen, Mingbo Bian, Yanpeng Ma, Huifang Wang, Haikuan Feng, Haikuan Feng, Haikuan Feng

“…Three types of spectral data—original spectral reflectance (OSR), first-order differential spectral reflectance (FDSR), and vegetation indices (VIs)—along with three types of Haralick textures—simple, advanced, and higher-order—were analyzed for their correlation with LAI across multiple growth stages. A model for LAI estimation in potato at multiple growth stages based on spectral and textural features screened by the successive projection algorithm (SPA) was constructed using partial least squares regression (PLSR), random forest regression (RFR) and gaussian process regression (GPR) machine learning methods. …”
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Accuracy and interpretability of smartwatch electrocardiogram for early detection of atrial fibrillation: A systematic review and meta‐analysis by Dr. Muhammad Iqhrammullah, Prof. Asnawi Abdullah, Dr. Hermansyah, Fahmi Ichwansyah, Prof. Dr. Ir. Hafnidar A. Rani, Meulu Alina, Artha M. T. Simanjuntak, Derren D. C. H. Rampengan, dr. Seba Talat Al‐Gunaid, dr. Naufal Gusti, dr. Arditya Damarkusuma, Edza Aria Wikurendra

“…Methods Data derived from indexed literature in the Scopus, Scilit, PubMed, Google Scholar, Web of Science, IEEE, and Cochrane Library databases (as of June 1, 2024) were systematically screened and extracted. The quantitative synthesis was performed using a two‐level mixed‐effects logistic regression model, as well as a proportional analysis with Freeman‐Tukey double transformation on a restricted maximum‐likelihood model. …”
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Geographic variation in secondary metabolites contents and their relationship with soil mineral elements in Pleuropterus multiflorum Thunb. from different regions by Yaling Yang, Siman Wang, Ruibin Bai, Feng Xiong, Yan Jin, Hanwei Liu, Ziyi Wang, Chengyuan Yang, Yi Yu, Apu Chowdhury, Chuanzhi Kang, Jian Yang, Lanping Guo

“…Conversely, a positive correlation was found between the contents of elements Na, Ce, Ti, and physcion and THSG-5, 2 components that exhibited higher levels in Deqing. Furthermore, an RF algorithm was employed to establish an interrelationship model, effectively forecasting the abundance of the majority of differential metabolites in HSW samples based on the content data of soil mineral elements. …”
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Prevalence estimates of trafficking in persons using statistical definitions: a cross-sectional high-risk community survey in Cape Town, South Africa by Rumi Kato Price, Annah K Bender, Floriana H Milazzo, Edna G. Rich, Nicolette V. Roman, Sheldon X Zhang, Erica L Koegler

“…Secondary outcome measures included individual and summary measures from the two screeners.Results Our PRIF algorithm yielded a TIP lifetime prevalence rate of 17.0% and past 12-month rate of 2.9%. …”
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Validation of a deep learning computer aided system for CT based lung nodule detection, classification, and growth rate estimation in a routine clinical population. by John T Murchison, Gillian Ritchie, David Senyszak, Jeroen H Nijwening, Gerben van Veenendaal, Joris Wakkie, Edwin J R van Beek

“…<h4>Objective</h4>In this study, we evaluated a commercially available computer assisted diagnosis system (CAD). The deep learning algorithm of the CAD was trained with a lung cancer screening cohort and developed for detection, classification, quantification, and growth of actionable pulmonary nodules on chest CT scans. …”
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Nitrogen content estimation of apple trees based on simulated satellite remote sensing data by Meixuan Li, Xicun Zhu, Xicun Zhu, Xinyang Yu, Cheng Li, Dongyun Xu, Ling Wang, Dong Lv, Yuyang Ma

“…Support Vector Machine (SVM) and Backpropagation Neural Network (BPNN) algorithms were used to construct and screen the optimal models for apple tree nitrogen content estimation.ResultsResults showed that visible light, red edge, near-infrared, and yellow edge bands were sensitive bands for estimating apple tree nitrogen content. …”
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RAD-Seq-derived SSR markers: a new paradigm for genetic analysis and construction of genetically improved production populations in Pinus koraiensis by Pingyu Yan, Wanying Zhang, Junfei Hao, Xiaotian Miao, Jun Wu, Zixiong Xie, Zhixin Li, Lei Zhang, Hanguo Zhang

“…A production population of 20 individuals was constructed via the simulated annealing algorithm, which exhibited a more reasonable mating system (F=−0.028) and demonstrated superior cone production compared with that of the plus tree population, with an increase of 79.6%. …”
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Machine learning for clustering and classification of early knee osteoarthritis using single-leg standing kinematics by Ui-Jae Hwang, Kyu Sung Chung, Sung-Min Ha

“…This study investigated the application of machine learning techniques to single-leg standing (SLS) kinematics to classify and predict EOA. (1) To identify distinct groups based on SLS kinematic patterns using unsupervised learning algorithms, (2) to develop supervised learning models to predict EOA status, and (3) to identify the most influential kinematic variables associated with EOA. …”
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