High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2... by Edelstein I.A., Gushchin A.E., Gladin D.P., Romanov A.V., Negasheva E.S., Frigo N.V., Kozlov R.S., Potekaev N.N., Kozlova N.S., Borukhovich D.G.

“…The most common combination of mutations was A2059G (23S rRNA) + S80I (parC), which made up to 33% (18/54) in St. Petersburg and 25.7% (25/97) in Moscow. …”
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Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis by Chengze Qiu, Zhiyong Zhang, Haocheng Wang, Na Liu, Ruixin Li, Zhiheng Wei, Benjie Wang, Nan Zhang

“…An artificial neural network model was constructed for the hub genes, and immune analysis was conducted using the ssGSEA algorithm. …”
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Improving synergistic drug combination prediction with signature-based gene expression features in oncology by Mozhgan Mozaffarilegha, Sajjad Gharaghani

“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
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Maximizing YOLOv2 efficiency: A study on multiclass detection of indoor objects by G Divya Deepak, Subraya Krishna Bhat

“…The objective of the present study is to present a systematic approach for optimizing the key hyperparameters of YOLOv2 model for multiclass object detection, specifically targeting seven classes of indoor objects: chair, fire extinguisher, printer, screen, trash bin, exit, and clock. …”
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Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target by Rendong Qu, Yiyan Zhang, Haojia Zhang, Ke Li, Boning Zhang, Hongxuan Tong, Tao Lu

“…Using differential expression analysis and machine learning algorithms, 12 potential hub genes were successfully screened. …”
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An EfficientNet integrated ResNet deep network and explainable AI for breast lesion classification from ultrasound images by Kiran Jabeen, Muhammad Attique Khan, Ameer Hamza, Hussain Mobarak Albarakati, Shrooq Alsenan, Usman Tariq, Isaac Ofori

“…Explainable artificial intelligence‐based analysed the performance of trained models. After that, a new feature selection technique is proposed based on the cuckoo search algorithm called cuckoo search controlled standard error mean. …”
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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders by Ziqin Yang, Ziqin Yang, Nicole A. Teaney, Nicole A. Teaney, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Mustafa Sahin, Mustafa Sahin, Mustafa Sahin, Wardiya Afshar-Saber, Wardiya Afshar-Saber

“…In this review, we compare two-dimensional and three-dimensional hiPSC formats for disease modeling, discuss the applications of functional assays, and offer insights on incorporating ML into hiPSC-based NDD research and drug screening.…”
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U-shaped relationship between frailty and non-HDL-cholesterol in the elderly: a cross-sectional study by Yu Pan, Yan Yuan, Juan Yang, Zhu Qing Feng, Xue Yin Tang, Yi Jiang, Gui Ming Hu, Jiang Chuan Dong

“…The variables underwent screening through Least Absolute Shrinkage and Selection Operator (LASSO) regression, univariate logistic regression, and Light Gradient Boosting Machine (LightGBM), with models developed through multivariate logistic regression and the LightGBM algorithm. …”
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Rapid Resilience Assessment and Weak Link Analysis of Power Systems Considering Uncertainties of Typhoon by Wenqing Ma, Xiaofu Xiong, Jian Wang

“…Second, for the resilience assessment process, the impact increment method is used to reduce the dimensionality of multiple fault state analysis in the power system, and resilience indexes are calculated by screening the contingency set based on depth-first traversal through a backtracking algorithm. …”
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Research and application of image recognition-based identification for flesh browning of loquat fruits by CHEN Yujia, DENG Chaojun, ZHANG Tingting, WANG Xiuping, CHEN Xiuping, ZHAO Jianing, MA Cuilan, JIANG Jimou

“…The Euclidean distance algorithm indicated that the percentage of browning area in the white flesh type was significantly higher than that in the red flesh type. …”
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Prevalence, types, risk factors and clinical correlates of anaemia in older people in a rural Ugandan population. by Joseph O Mugisha, Kathy Baisley, Gershim Asiki, Janet Seeley, Hannah Kuper

“…Clinicians should consider screening older people with HIV or malaria for anaemia. …”
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High-throughput discovery of genetic determinants of circadian misalignment. by Tao Zhang, Pancheng Xie, Yingying Dong, Zhiwei Liu, Fei Zhou, Dejing Pan, Zhengyun Huang, Qiaocheng Zhai, Yue Gu, Qingyu Wu, Nobuhiko Tanaka, Yuichi Obata, Allan Bradley, Christopher J Lelliott, Sanger Institute Mouse Genetics Project, Lauryl M J Nutter, Colin McKerlie, Ann M Flenniken, Marie-France Champy, Tania Sorg, Yann Herault, Martin Hrabe De Angelis, Valerie Gailus Durner, Ann-Marie Mallon, Steve D M Brown, Terry Meehan, Helen E Parkinson, Damian Smedley, K C Kent Lloyd, Jun Yan, Xiang Gao, Je Kyung Seong, Chi-Kuang Leo Wang, Radislav Sedlacek, Yi Liu, Jan Rozman, Ling Yang, Ying Xu

“…We developed a machine learning algorithm to quantify these two parameters in our misalignment screen (SyncScreener) with existing datasets and used it to screen 750 mutant mouse lines from five IMPC phenotyping centres. …”
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Atrial fibrillation with thrombotic complications. Justification of the diagnosis and treatment regimen according to evidence-based medicine (clinical case) by L.O. Martymianova, E.P. Kamenska, A.O. Bulyha, K.О. Serdyuk

“…Diagnosis and systematic screening of AF, as well as timely assessment of stroke risk, are of paramount importance for the prognosis of patients, especially in older age groups. …”
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Research on the Evaluation of the Node Cities of China Railway Express Based on Machine Learning by Chenglin Ma, Mengwei Zhou, Wenchao Kang, Haolong Wang, Jiajia Feng

“…The Random Forest model outperformed comparative algorithms with 99.5% prediction accuracy (8.33% higher than conventional classification models), particularly in handling multi-dimensional interactions between urban development factors. …”
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Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes. by Taole Li, Jifeng Guo

“…According to the five machine algorithms, 4 features (S100A2, GNGT1, NEUROD4, FCN2) were screened and used to create a PD diagnostic model. …”
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Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data by Jialiang Lin, Linjuan Huang, Weiming Li, Haijun Xiao, Mingmang Pan

“…Furthermore, in vitro experiments successfully established a DFU oxidative stress model of fibroblasts, revealing reduced migration ability in the absence of cell death. …”
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Association between pace of biological aging and cancer and the modulating role of physical activity: a national cross-sectional study by Jingying Nong, Yu Wang, Yi Zhang

“…Epigenetic clocks, derived from sets of DNA methylation CpGs and mathematical algorithms, have demonstrated a remarkable ability to indicate biological aging and age-related health risks. …”
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Will Artificial Intelligence Replace Physicians or Augment Their Capabilities? by Sara Rahmati Roodsari, Alireza Zali, Mohammad Rahmati-Roodsari, Behina Forouzanmehr

“…In medical imaging, deep learning algorithms, especially those trained with genetic algorithms, have demonstrated immense promise to improve the accuracy of pneumonia and COVID-19 diagnosis from chest X-rays. …”
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Unveiling the ageing-related genes in diagnosing osteoarthritis with metabolic syndrome by integrated bioinformatics analysis and machine learning by Jian Huang, Lu Wang, Jiangfei Zhou, Tianming Dai, Weicong Zhu, Tianrui Wang, Hongde Wang, Yingze Zhang

“…The limma package was used to identify differentially expressed genes (DEGs), and weighted gene coexpression network analysis (WGCNA) screened gene modules, and machine learning algorithms, such as random forest (RF), support vector machine (SVM), generalised linear model (GLM), and extreme gradient boosting (XGB), were employed. …”
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Artificial Intelligence Powered Automated and Early Diagnosis of Acute Lymphoblastic Leukemia Cancer in Histopathological Images: A Robust SqueezeNet-Enhanced Machine Learning Fram... by Vineet Mehan

“…The growing prevalence of acute lymphoblastic leukemia cancer worldwide underlines the critical need for early and more precise detection to counter this deadly disease. …”
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