Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking ap... by Shu-jie Yu, Xiao-bin Kong, Xin Jin, Meng-yi Shan, Gang Cheng, Pei-lu Wang, Wen-long Li, Pei-yuan Zhao, Yun-jie Sheng, Bing-qian He, Qi Shi, Hua-qiang Li, Qi-ming Zhao, Lu-ping Qin, Lu-ping Qin, Xiong-yu Meng, Xiong-yu Meng

“…As a result, the material–liquid ratio was significantly reduced from 100 g/mL to 32 g/mL, and the extraction efficiency was 1.332%, which was close to the predicted value of 1.346% in the response surface method, indicating that the algorithm model had a good fit. Next, a total of 738 compounds, including 161 terpenoids, 144 phenolic acids, 51 alkaloids, 24 flavonoids, 34 saccharides, 32 lignans and coumarins, 45 amino acids and derivatives, 23 organic acids, 134 lipids, 22 nucleotides and derivatives, and 59 other ingredients, were characterized from Scrophulariae Radix based on the accurate precursor and product ions, retention time, standards, fragmentation patterns, and previous publications. …”
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Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation by Guiling Wu, Guiling Wu, Sihui Wu, Sihui Wu, Tian Xiong, Tian Xiong, Tian Xiong, You Yao, You Yao, Yu Qiu, Yu Qiu, Yu Qiu, Liheng Meng, Cuihong Chen, Xi Yang, Xi Yang, Xi Yang, Xinghuan Liang, Yingfen Qin

“…Candidate biomarkers were screened using machine learning algorithms combined with 12 cytoHubba algorithms, and a diagnostic model for T2DM-related MAFLD was constructed and evaluated.The CIBERSORT method was used to investigate immune cell infiltration in MAFLD and the immunological significance of central genes. …”
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Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

“…Additionally, the least absolute shrinkage and selection operator (LASSO) regression algorithm in machine learning was used to screen transcription factors such as bHLH, WRKY, and MYB that influenced the expression of TaAkPHY genes. …”
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Identification of Serum miRNAs as Effective Diagnostic Biomarkers for Distinguishing Primary Central Nervous System Lymphoma from Glioma by Pei-pei Si, Xiao-hui Zhou, Zhen-zhen Qu

“…Candidate miRNAs were identified through SVM-RFE analysis and LASSO model. ROC assays were operated to determine the diagnostic value of serum miRNAs in distinguishing PCNSL from glioma. …”
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Mapping the digital silk road: evolution and strategic shifts in Chinese social media marketing (2015–2025) by Xinrui Liang, Wan Mohd Hirwani Wan Hussain, Mohammed R. M. Salem

“…Following Arksey and O’Malley’s five-stage scoping framework, 3,710 records from Web of Science and Scopus were screened, yielding 41 peer-reviewed studies. Results indicate a transition from search-based behaviour to AI-facilitated impulse purchasing, enabled by algorithmic recommendations, parasocial influencer relations, and livestream commerce. …”
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A beginner’s approach to deep learning applied to VS and MD techniques by Stijn D’Hondt, José Oramas, Hans De Winter

“…There are many ways in which DL can be applied to these molecular modelling techniques to achieve more accurate results in a more efficient manner or expedite the data analysis of the acquired results. …”
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Rapid Detection of Antibiotic Mycelial Dregs Adulteration in Single-Cell Protein Feed by HS-GC-IMS and Chemometrics by Yuchao Feng, Yang Li, Wenxin Zheng, Decheng Suo, Ping Gong, Xiaolu Liu, Xia Fan

“…In addition, the feasibility of quantitative analysis of the AMDs content in adulterated SCPF based on partial least squares regression (PLSR) algorithm. In total, 88 volatile organic compounds (VOCs) were detected. …”
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Maternal factors associated with early-onset neonatal sepsis among caesarean-delivered babies at Mbarara Regional Referral Hospital, Uganda: a case-control study by James M. Maisaba, Richard Migisha, Asiphas Owaraganise, Leevan Tibaijuka, David Collins Agaba, Joy Muhumuza, Joseph Ngonzi, Stella Kyoyagala, Musa Kayondo

“…We enrolled mother-baby pairs for both groups, obtaining maternal data via structured questionnaires The diagnosis of EONS was made using the WHO Young Infant Integrated Management of Childhood Illnesses algorithm. …”
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The performance of artificial intelligence in image-based prediction of hematoma enlargement: a systematic review and meta-analysis by Wenjing Fan, Zhiping Wu, Wangyang Zhao, Luzhu Jia, Shuze Li, Wei Wei, Xin Chen

“…Two reviewers independently screened the retrieved citations and extracted data. …”
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Miniaturized Near-Infrared Analyzer for Quantitative Detection of Trace Water in Ethylene Glycol by Qunling Luo, Zhiqiang Guo, Danping Lin, Boxue Chang, Yinlan Ruan

“…To address the limitations of a traditional Fourier-transform infrared (FTIR) spectrometer, including its bulky size, high cost, and unsuitability for on-site industrial detection, this study developed a Fourier-transform near-infrared (FT-NIR) absorption testing system utilizing Micro-Electro-Mechanical System (MEMS) technology for detecting trace water content in ethylene glycol. The modeling performances of three algorithms including Support Vector Machine Regression (SVMR), Principal Component Regression (PCR), and Partial Least Squares Regression (PLSR) were systematically evaluated, with PLSR identified as the optimal algorithm. …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Patients whose PCP was contacted were more likely to have adjustments made to their lipid lowering medication(s) (p = 0.016), be diagnosed with FH (p = 0.025), and have a follow-up visit (p = 0.033). …”
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Estimation of the aboveground carbon stocks based on tree species identification in Saihanba plantation forest by Ao Zhang, Xiaohong Wang, Xin Gu, Xiangyao Xu, Xintong Gao, Linlin Jiao

“…The results were shown that: 1) The identification effect of Scheme IV, as ascertained by screening three types of effective feature vectors based on the random forest algorithm, was the most effective, with an overall accuracy (OA) and kappa coefficient of 89.7% and 0.863, respectively. …”
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Machine learning in dentistry and oral surgery: charting the course with bibliometric insights by Shuangwei Liu, Yuquan Hao, Shijie Zhu, Liyao Wan, Zhe Yi, Zhichang Zhang

“…Moreover, challenges, such as data availability and security, algorithmic biases, and “black-box models”, must be addressed. …”
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Robust Bi-CBMSegNet framework for advancing breast mass segmentation in mammography with a dual module encoder-decoder approach by Yu Wang, Mudassar Ali, Tariq Mahmood, Amjad Rehman, Tanzila Saba

“…Current target detection algorithms have limited applications and low accuracy. …”
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Identification of Ferroptosis‐Related Gene in Age‐Related Macular Degeneration Using Machine Learning by Meijiang Zhu, Jing Yu

“…Differentially expressed genes (DEGs) were selected and intersected with genes from the ferroptosis database to obtain differentially expressed ferroptosis‐associated genes (DEFGs). Machine learning algorithms were employed to screen diagnostic genes. …”
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Diagnostic Value of F-FDG PET/CT Radiomics in Lymphoma: A Systematic Review and Meta-Analysis by Chaoying Liu MD, Jun Zhao PhD, Heng Zhang PhD, Xinye Ni PhD

“…Six meta-regressions were conducted on study performance, considering sample size, image modality, region of interest (ROI) selection, ROI segmentation, radiomics mode, and algorithms. Results In total, 20 studies classified as type 2a or above according to the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement were included for this systematic review and meta-analysis. …”
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Mechanism and relevance of necroptosis to immune microenvironment of periodontitis: A pilot study by ZHENG Zhanglong, LI Jia, JIANG Jirui, SHAN Zhengnan, LI Shengjiao

“…[Objective:] To explore the effect and mechanism of necroptosis on the immune microenvironment of periodontitis. [Methods:] We screened out the differentially expressed necroptosis-related genes in periodontitis, first calculated the hub genes through machine learning algorithms, and constructed a diagnostic model. …”
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Artificial intelligence technology in ophthalmology public health: current applications and future directions by ShuYuan Chen, Wen Bai, Wen Bai

“…Key issues include interoperability with electronic health records (EHR), data security and privacy, data quality and bias, algorithm transparency, and ethical and regulatory frameworks. …”
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Advancements in Machine Learning (ML): Transforming the Future of Blood Cancer Detection and Outcome Prediction by Wiebke Rösler, Michael Roiss, Corinne Widmer

“…The diagnosis and treatment of hematologic malignancies are becoming more and more complex. Growing knowledge of pathophysiology, diagnostic methods and, last but not least, treatment options offer many opportunities for patients, but integrating the growing amount of knowledge into daily practice can be challenging. …”
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Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches by Jiayi Zhang, Zhixiang Jia, Jiahui Zhang, Xiaohui Mu, Limei Ai

“…Using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine Recursive Feature Elimination (SVM-RFE), and Random Forest (RF) algorithms, we screened for seven potential diagnostic biomarkers with strong diagnostic capabilities: SMAD3, IL7R, IL18, FAS, CD5, CCR7, and CSF1R. …”
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