Signatures of Six Autophagy‐Related Genes as Diagnostic Markers of Thyroid‐Associated Ophthalmopathy and Their Correlation With Immune Infiltration by Qintao Ma, Yuanping Hai, Jie Shen

“…The combined six‐gene model also showed good diagnostic efficacy (AUC = 0.948). …”
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Identifying and Validating an Acidosis-Related Signature Associated with Prognosis and Tumor Immune Infiltration Characteristics in Pancreatic Carcinoma by Pingfei Tang, Weiming Qu, Dajun Wu, Shihua Chen, Minji Liu, Weishun Chen, Qiongjia Ai, Haijuan Tang, Hongbing Zhou

“…Univariate Cox regression and the Kaplan–Meier method were applied to screen for prognostic genes. The least absolute shrinkage and selection operator (LASSO) Cox regression was used to establish the optimal model. …”
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Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics by Haiting Ye, Xiang Zhang, Pengyan Li, Mei Wang, Ruolan Liu, Dingping Yang

“…Immune cell infiltration was analyzed using the CIBERSORT algorithm, and potential associations between the hub genes and clinicopathological features were explored based on the Nephroseq database. …”
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Cell death-related signature genes: risk-predictive biomarkers and potential therapeutic targets in severe sepsis by Yanan Li, Yuqiu Tan, Zengwen Ma, Zengwen Ma, Weiwei Qian, Weiwei Qian

“…Further combining cell death-related gene screening and four machine learning algorithms (including LASSO-logistic, Gradient Boosting Machine, Random Forest and xGBoost), nine SeALAR-characterized cell death genes (SeDGs) were screened and a risk prediction model based on SeDGs was constructed that demonstrated good prediction performance. …”
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Opening closed doors: using machine learning to explore factors associated with marital sexual violence in a cross-sectional study from India by Anita Raj, Abhishek Singh, Nandita Bhan, Lotus McDougal, Nabamallika Dehingia, Julian McAuley

“…Analyses included iterative thematic analysis (L-1 regularised regression followed by iterative qualitative thematic coding of L-2 regularised regression results) and neural network modelling.Outcome measure Participants reported their experiences of sexual violence perpetrated by their current (or most recent) husband in the previous 12 months. …”
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Improving the accuracy of remotely sensed TSS and turbidity using quality enhanced water reflectance by a statistical resampling technique by Kunwar Abhishek Singh, Dongryeol Ryu, Meenakshi Arora, Manoj Kumar Tiwari, Bhabagrahi Sahoo

“…The statistical resampling approach based on GMM was applied to Sentinel-2 (S2) imagery to produce input to Machine Learning (ML) algorithms to retrieve the TSS and turbidity for target river sections. …”
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Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review by Martins Nweke, Nombeko Mshunqane

“…Predictive and preventative models should target factors with a high causality index and low investigative costs. …”
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Individual differences in response to alcohol exposure in zebrafish (Danio rerio). by Heloysa Araujo-Silva, Jaquelinne Pinheiro-da-Silva, Priscila F Silva, Ana C Luchiari

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Molecular epidemiology of enteroviruses from Guatemalan wastewater isolated from human lung fibroblasts. by Leanna Sayyad, Chelsea Harrington, Christina J Castro, Hanen Belgasmi-Allen, Stacey Jeffries Miles, Jamaica Hill, María Linda Mendoza Prillwitz, Lorena Gobern, Ericka Gaitán, Andrea Paola Delgado, Leticia Castillo Signor, Marc Rondy, Gloria Rey-Benito, Nancy Gerloff

“…Murine recombinant fibroblast L-cells (L20B) and human rhabdomyosarcoma (RD) cells are used for the isolation of polioviruses following a standard detection algorithm. Though non-polio-Enteroviruses (NPEV) can be isolated, the algorithm is optimized for the detection of polioviruses. …”
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A nicotinamide metabolism-related gene signature for predicting immunotherapy response and prognosis in lung adenocarcinoma patients by Meng Wang, Wei Li, Fang Zhou, Zheng Wang, Xiaoteng Jia, Xingpeng Han

“…Four independent prognostic NMRGs (GJB3, CPA3, DKK1, KRT6A) were screened and used to construct a RiskScore model, which exhibited a strong predictive performance. …”
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Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium by Kun Gao, Zhenyu Huang, Zhouwei Liao, Yanfei Wang, Dayu Chen

“…We employed several machine learning algorithms, including least absolute shrinkage and selection operator and support vector machine–recursive feature elimination, to screen for key genes. …”
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Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma by Duo Wang, Duo Wang, Duo Wang, Jihao Tu, Jihao Tu, Jianfeng Liu, Jianfeng Liu, Yuting Piao, Yuting Piao, Yiming Zhao, Yiming Zhao, Ying Xiong, Ying Xiong, Jianing Wang, Jianing Wang, Xiaotian Zheng, Xiaotian Zheng, Bin Liu, Bin Liu

“…We developed a novel machine learning framework that incorporated 12 machine learning algorithms and their 127 combinations to construct a consensus GPRS to screen biomarkers with diagnostic significance and clinical translation, which was assessed by the internal and external validation datasets. …”
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Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis by Chengze Qiu, Zhiyong Zhang, Haocheng Wang, Na Liu, Ruixin Li, Zhiheng Wei, Benjie Wang, Nan Zhang

“…An artificial neural network model was constructed for the hub genes, and immune analysis was conducted using the ssGSEA algorithm. …”
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Diagnosing cystic fibrosis in low- and middle-income countries: challenges and strategies by Michèle Fuhrer, Marco Zampoli, Hugues Abriel

“…Recent evidence indicates that Cystic Fibrosis is more common than initially thought and is likely underreported in low- and middle-income countries. …”
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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders by Ziqin Yang, Ziqin Yang, Nicole A. Teaney, Nicole A. Teaney, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Mustafa Sahin, Mustafa Sahin, Mustafa Sahin, Wardiya Afshar-Saber, Wardiya Afshar-Saber

“…In this review, we compare two-dimensional and three-dimensional hiPSC formats for disease modeling, discuss the applications of functional assays, and offer insights on incorporating ML into hiPSC-based NDD research and drug screening.…”
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Accuracy and interpretability of smartwatch electrocardiogram for early detection of atrial fibrillation: A systematic review and meta‐analysis by Dr. Muhammad Iqhrammullah, Prof. Asnawi Abdullah, Dr. Hermansyah, Fahmi Ichwansyah, Prof. Dr. Ir. Hafnidar A. Rani, Meulu Alina, Artha M. T. Simanjuntak, Derren D. C. H. Rampengan, dr. Seba Talat Al‐Gunaid, dr. Naufal Gusti, dr. Arditya Damarkusuma, Edza Aria Wikurendra

“…Methods Data derived from indexed literature in the Scopus, Scilit, PubMed, Google Scholar, Web of Science, IEEE, and Cochrane Library databases (as of June 1, 2024) were systematically screened and extracted. The quantitative synthesis was performed using a two‐level mixed‐effects logistic regression model, as well as a proportional analysis with Freeman‐Tukey double transformation on a restricted maximum‐likelihood model. …”
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Nitrogen content estimation of apple trees based on simulated satellite remote sensing data by Meixuan Li, Xicun Zhu, Xicun Zhu, Xinyang Yu, Cheng Li, Dongyun Xu, Ling Wang, Dong Lv, Yuyang Ma

“…Support Vector Machine (SVM) and Backpropagation Neural Network (BPNN) algorithms were used to construct and screen the optimal models for apple tree nitrogen content estimation.ResultsResults showed that visible light, red edge, near-infrared, and yellow edge bands were sensitive bands for estimating apple tree nitrogen content. …”
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Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data by Jialiang Lin, Linjuan Huang, Weiming Li, Haijun Xiao, Mingmang Pan

“…Furthermore, in vitro experiments successfully established a DFU oxidative stress model of fibroblasts, revealing reduced migration ability in the absence of cell death. …”
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Association between pace of biological aging and cancer and the modulating role of physical activity: a national cross-sectional study by Jingying Nong, Yu Wang, Yi Zhang

“…Epigenetic clocks, derived from sets of DNA methylation CpGs and mathematical algorithms, have demonstrated a remarkable ability to indicate biological aging and age-related health risks. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…Abnormal liver functional tests were revealed in 30,6% of industrial city inhabitants — in 1461 of 4768 cases (232 patients were excluded from the study due to partial data loss), significantly more frequently in men in comparison to women, i.e. 49,7 and 25,5% respectively (p<0,001). …”
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