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561
Expression signatures with specificity for type I and II IFN response and relevance for autoimmune diseases and cancer
Published 2025-07-01“…Our IFN-II signature is broader applicable than other published signatures as it demonstrates strong performance in detecting IFN-II response in more cell types. In three SLE microarray datasets our IFN-I signature was highly coherent and correlated with disease severity better than most published signatures. …”
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562
MicroRNA markers for the diagnosis of pancreatic and biliary-tract cancers.
Published 2015-01-01“…It is difficult to detect pancreatic cancer or biliary-tract cancer at an early stage using current diagnostic technology. …”
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563
High prevalence of p16 staining in malignant tumors.
Published 2022-01-01“…However, the prevalence of p16 expression in different cancer types is controversial. 15,783 samples from 124 different tumor types and 76 different normal tissue types were analyzed by immunohistochemistry in a tissue microarray format. p16 was detectable in 5,292 (45.0%) of 11,759 interpretable tumors. …”
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564
Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression
Published 2025-01-01“…Therefore, we identified circHIF-1α, hsa_circ_0007976, which was downregulated in senescent cells using circRNA microarray analysis. Meanwhile, significantly upregulated expression of circHIF-1α in pancreatic cancer tissue detected by reverse transcription-polymerase chain reaction (RT-qPCR) and in situ hybridization (ISH). …”
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565
Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation.
Published 2016-01-01“…The WT dams had no detectable hNAG-1 in the milk. A decrease in non-esterified free fatty acids in the milk of hNAG-1 dams was observed. …”
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566
The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus–positive and –negative oropharyngeal squamous cell carcinoma
Published 2019-03-01“…Human papillomavirus is detected in over 50% of oropharyngeal squamous cell carcinomas. …”
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567
Caveolin-1 inhibits the proliferation and invasion of lung adenocarcinoma via EGFR degradation
Published 2025-07-01“…The expressions of CAV1 and EGFR in LUAD tissues and adjacent tissues were detected by Western blotting, immunohistochemistry and microarray technology. …”
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568
Array-CGH increased the diagnostic rate of developmental delay or intellectual disability in Taiwan
Published 2019-08-01“…Key Words: array-CGH, chromosomal microarray, developmental delay, intellectual disabilities, Taiwan…”
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569
Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
Published 2019-03-01“…Methods We downloaded the microarray data from the Gene Expression Omnibus (GEO) database. …”
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570
Electrochemical Strategies for MicroRNA Quantification Leveraging Amplification and Nanomaterials: A Review
Published 2025-07-01“…However, conventional detection methods, such as Northern blotting, RT-PCR, and microarrays, are limited by low sensitivity, lengthy protocols, and limited specificity. …”
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571
Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas
Published 2012-01-01“…A cytoplasmic β-catenin pool was detectable in 13/15 cultures leading to some transcriptional activity assessed by luciferase reporter gene assay in 8/13. …”
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572
Over Time Changes in the Transcriptomic Profiles of Tomato Plants with or Without <i>Mi-1</i> Gene During Their Incompatible or Compatible Interactions with the Whitefly <i>Bemisia...
Published 2025-03-01“…Motelle, incompatible interaction) was studied using the oligonucleotide microarray technique. Both interactions were studied 2 and 12 days post infestation (dpi) of plants with adult insects. …”
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573
Effects of Benzo[a]Pyrene Exposure on Lung Cancer: A Mechanistic Study of Epigenetic m6A Levels and YTHDF1
Published 2025-04-01“…TMT labeling-based proteomic analysis and clinical lung tissue microarray assays demonstrated that CDK6 and MAP3K6 were positively correlated with YTHDF1 expression. …”
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574
Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies
Published 2025-01-01“…They often require karyotyping, fluorescence in situ hybridization, and chromosomal microarray analysis (CMA) for clinical diagnosis because of the limitations of each method. …”
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575
MicroRNA let-7f protects against H2O2-induced oxidative damage in neuroblastoma cells by targeting AKT-2
Published 2020-04-01“…Material and methods miRNA microarray analysis was performed to detect the miRNAs’ differential expression in AD patients and normal elderly volunteers. …”
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576
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis
Published 2025-02-01“…Methods TCGA public database and a tissue microarray were used to investigate the molecular characteristics of CLIP4 and its association with disease. …”
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577
Identification and validation of hub genes associated with biotic and abiotic stresses by modular gene co-expression analysis in Oryza sativa L.
Published 2025-03-01“…A total of 11, 12, 46, and 14 modules containing 85, 106, 253, and 143 hub genes were detected in drought, salinity, tungro virus, and blast. …”
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578
Expression and clinical significance of FGL1 and YAP1 in colorectal cancer
Published 2025-07-01“…<b>Methods</b> Tissue microarray technique was used to detect FGL1 and YAP1 expression in 101 colorectal cancer tissues and 79 adjacent tissues from June 2007 to April 2008. …”
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579
New Frontiers for the Early Diagnosis of Cancer: Screening miRNAs Through the Lateral Flow Assay Method
Published 2025-04-01“…This review focuses on LFA-based methods for detecting and quantifying miRNAs associated with the diagnosis of various cancers, with particular emphasis on sensitivity enhancements achieved through the application of different labels and detection systems. …”
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580
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Published 2013-01-01“…We used live-cell imaging and high content image analysis tools and identified JNJ-10198409 (J101) as an agent that induces mitotic arrest at prometaphase in GNS cells but not NS cells. Antibody microarrays and kinase profiling suggested that J101 responses are triggered by suppression of the active phosphorylated form of polo-like kinase 1 (Plk1) (phospho T210), with resultant spindle defects and arrest at prometaphase. …”
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