-
41
A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
Published 2024-12-01“…In this study, we introduce a custom-designed lectin microarray featuring nine distinct lectins: rPhoSL, rOTH3, RCA120, rMan2, MAL_I, rPSL1a, PHAE, rMOA, and PHAL. …”
Get full text
Article -
42
CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
Get full text
Article -
43
THE VALIDATION OF THE RESULTS OF MICROARRAY STUDIES OF ASSOCIATION BETWEEN GENE POLYMORPHISMS AND THE FREQUENCY OF RADIATION EXPOSURE MARKERS
Published 2014-06-01“…The results from the selective validation research into the association between genetic polymorphisms and the frequency of cytogenetic abnormalities on a large independent sample are analyzed. …”
Get full text
Article -
44
Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…An artificial neural network (ANN) model trained on microarray gene expression data determined minimal gene combinations for each subgroup. …”
Get full text
Article -
45
Discovery of possible gene relationships through the application of self-organizing maps to DNA microarray databases.
Published 2014-01-01“…DNA microarrays and cell cycle synchronization experiments have made possible the study of the mechanisms of cell cycle regulation of Saccharomyces cerevisiae by simultaneously monitoring the expression levels of thousands of genes at specific time points. …”
Get full text
Article -
46
Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays.
Published 2011-01-01“…<h4>Experimental design</h4>A search of publicly available databases was performed to identify microarray datasets with multiple histologic sub-types of renal cortical neoplasms. …”
Get full text
Article -
47
Microarray Core Detection by Geometric Restoration
Published 2012-01-01“…Furthermore, the algorithm is more efficient than existing methods based on the Hough transform for circle detection. The algorithm’s simplicity, accuracy, and computational efficiency allow for automated high-throughput analysis of microarray images.…”
Get full text
Article -
48
Expression of long non-coding RNA in patients with non-IgA mesangial proliferative glomerulonephritis
Published 2015-01-01“…Objective To study differential expression profile of mRNA and long non-coding RNA(IncRNA) through microarray analysis between non-IgA mesangial proliferative glomerulonephritis(MsPGN) patients and the controls,and then explore the potential role of IncRNA in the pathogenesis of non-IgA MsPGN.Methods Through simple random sampling,4 patients with non-IgA MsPGN and 2 controls were selected as disease group and control group,respectively.Renal cortical tissues from two groups were collected.Total RNA was extracted,quantified and prepared to ds-cDNA through reverse transcription ds-cDNA was labeled with NimbleGen one-color DNA labeling kit and used for array hybridization.All experimental data were processed through GO analysis,Pathway analysis and the gene loci correlation analysis of mRNA and IncRNA.Some IncRNAs that were closely related to non-IgA MsPGN were screened out.Finally,part of the array results was detected by PCR to verify the reliability of array test Results By fold change filtering,4317 differentially expressed mRNAs and 3502 differentially expressed IncRNAs were screened out.Five IncRNAs were found to play potential roles in the pathogenesis of non-IgA MsPGN:AF1180924(close to coding gene FGG),AK092233(close to coding gene COL18A1),AK130579(close to coding gene CREBBP),AK023598(close to coding gene LEPR),and AK055915(close to coding gene CDC42EP3).These results provided an important basis for revealing the pathogenesis of non-IgA MsPGN.Conclusions Some IncRNAs can potentially regulate related genes and plays an important role in the pathogenesis and development of non-IgA MsPGN.…”
Get full text
Article -
49
Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer
Published 2015-01-01“…Using carbohydrate microarrays, we explored potential natural ligands of antitumor monoclonal antibody HAE3. …”
Get full text
Article -
50
-
51
-
52
IDENTIFYING IMPORTANT GENES IN OVARIAN CANCER FROM HIGH-DIMENSIONAL MICROARRAY DATA USING SIFS-CART METHOD
Published 2024-07-01“…Ovarian cancer can be identified from microarray data using machine learning. Many studies only focus on improving the machine learning classification algorithms to achieve higher performance. …”
Get full text
Article -
53
Photopolymerization as an innovative detection technique for low-density microarrays
Published 2008-08-01“…One limitation that accounts in part for the scarcity of commercially available diagnostic microarrays is the expense associated with fluorescence detection. …”
Get full text
Article -
54
RETRACTED ARTICLE: Multi-stage biomedical feature selection extraction algorithm for cancer detection
Published 2023-04-01“…Abstract Cancer is a significant cause of death worldwide. Early cancer detection is greatly aided by machine learning and artificial intelligence (AI) to gene microarray data sets (microarray data). …”
Get full text
Article -
55
Multiplex peptide microarray profiling of antibody reactivity against neglected tropical diseases derived B-cell epitopes for serodiagnosis in Zimbabwe.
Published 2022-01-01“…In this framework, we present a pilot study to design and produce a peptide microarray for the integrated surveillance of neglected tropical diseases. …”
Get full text
Article -
56
-
57
Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells.
Published 2012-01-01“…Here we show, and experimentally verify, that cryptic repetitive element probes present in Illumina and Affymetrix gene expression microarray platforms can accurately and sensitively monitor repetitive element expression data. …”
Get full text
Article -
58
-
59
Candidate Anxiety‐Related Genes in the Hippocampus of Hatano Male Rats: Anxiolytic Action of Neuromedin U in the Hippocampus
Published 2025-06-01“…The present study focuses on the hippocampus, which is associated with anxiety‐like behavior, and used microarray analysis and RT‐qPCR to select genes with differential expression in the hippocampus between HAA and LAA (Experiment 1). …”
Get full text
Article -
60
CCD Standard Curve Fitting for Microarray Detection Base on Multi-Layer Perceptron
Published 2024-01-01“…The gray-level of the fluorescent probe in detection image was obtained as the data set acquired by the microarray scanner at different exposure time. …”
Get full text
Article