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321
Amogel: a multi-omics classification framework using associative graph neural networks with prior knowledge for biomarker identification
Published 2025-03-01“…Abstract The advent of high-throughput sequencing technologies, such as DNA microarray and DNA sequencing, has enabled effective analysis of cancer subtypes and targeted treatment. …”
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322
Mutation Spectrum of the ABCA4 Gene in a Greek Cohort with Stargardt Disease: Identification of Novel Mutations and Evidence of Three Prevalent Mutated Alleles
Published 2018-01-01“…A total of 59 patients were analyzed for ABCA4 mutations using the ABCR400 microarray and PCR-based sequencing of all coding exons and flanking intronic regions. …”
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323
Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker.
Published 2013-01-01“…Six genes identified by microarray as highly expressed in HH-HCC were confirmed by RT qPCR. …”
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324
Differentially expressed miR-3680-5p is associated with parathyroid hormone regulation in peritoneal dialysis patients.
Published 2017-01-01“…Total RNA from 15 patients (7 and 8 patients in the low and high iPTH groups, respectively) underwent miRNA microarray analysis, and three differentially upregulated (>2-fold change) miRNAs previously associated with human disease were selected for real-time quantitative PCR (qPCR) analysis. …”
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325
Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells
Published 2017-01-01“…Purpose. To investigate the effect of rho kinase inhibitors on oxidative stress in trabecular meshwork (TM) cells. …”
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326
TRIM22 promotes glioblastoma development by ubiquitinating Bcl-2
Published 2025-12-01“…A TRIM22-overexpressing ubiquitination microarray identified TRIM22 as a potential activator of Bcl-2. …”
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327
Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
Published 2022-11-01“…Material and methods. a total of 130 breast cancer patients were included in the study. microarray analysis was performed on Affymetrix Cytoscantm HD Array high-density DNA chips to assess LOH status. …”
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328
FAM111B knockdown attenuates tumorigenesis of ovarian cancer via the downregulation of MYC
Published 2025-08-01“…Immunohistochemical analyses conducted on tissue-microarray samples obtained from patients with serous ovarian cancer indicated that elevated levels of FAM111B expression were associated with unfavorable prognostic outcomes. …”
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329
Global challenges and solutions to achieving and sustaining measles and rubella elimination
Published 2024-12-01“…Progress will be supported through technological innovations such as microarray patch vaccines. Whether this holistic approach will be more effective than vertical initiatives at achieving measles and rubella elimination remains to be seen. …”
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330
Investigation on the Electron Emission Regularity of Sputtered Boron Nitride Thin Films and Microstructured Array Surfaces
Published 2025-03-01“…The results of laser etching on the BN bulk surface to form microarray structures show that the EEC of BN bulk decreases significantly with the increase of the average aspect ratio of the microstructures. …”
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331
Poly-β-D-(1,6)-N-acetyl-glucosamine (PNAG) glycan vaccines with broad spectrum neutralizing activities
Published 2025-07-01“…Glycan microarray analysis shows that dPNAG glycans with DP8 and DP12 are optimal, with corresponding protein conjugates eliciting the highest IgG titers. …”
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332
Gene co-expression module study identifies key genes and pathways underpinning hypercholesterolemia-induced atherosclerosis development
Published 2025-07-01“…Methods The Affymetrix microarray dataset (GSE13985), which includes samples from five healthy controls and five FH patients, was obtained from the Gene Expression Omnibus (GEO) database. …”
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333
Identification of Key Genes and Potential Therapeutic Targets in Sepsis-Associated Acute Kidney Injury Using Transformer and Machine Learning Approaches
Published 2025-05-01“…Early diagnosis and effective therapy remain difficult despite extensive investigation. …”
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334
Genetic testing for oral clefts: reflections based on a single Brazilian public genetics service
Published 2025-08-01“…They also show the need to improve public health policies for genetic evaluation, diagnostic tests, and genetic counseling for an effective NPCCPRD.…”
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335
The Necessity of Prenatal Diagnosis by CMA for the Women with NIPS-Positive Results
Published 2020-01-01“…Single nucleotide polymorphism array testing was performed on a commercial 750K microarray chip (Affymetrix CytoScan 750K Array). Results. …”
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336
VEGF Contributes to Mesenchymal Stem Cell-Mediated Reversion of Nor1-Dependent Hypertrophy in iPS Cell-Derived Cardiomyocytes
Published 2021-01-01“…Phenylephrine (PE) was used to induce hypertrophy in murine iPS-CM, and markers of hypertrophy were identified by microarray analysis. Murine MSCs were treated with IFN-γ and IL-1β to enhance their paracrine activity, and transcriptional profiling was performed by microarray analysis. …”
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337
Exploration of the shared gene signatures and comorbidity mechanisms of primary aldosteronism and atrial fibrillation
Published 2024-12-01“…These hub genes were subsequently validated via two independent external datasets: GSE60042 (PA microarray dataset) and GSE41177 (AF microarray dataset). …”
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338
Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts
Published 2020-01-01“…Here, we aimed to explore the genome-wide effects of PPARγ on EVCTs and VCTs via treatment with the PPARγ-agonist rosiglitazone. …”
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339
Downregulation of sorting nexin 10 is associated with overexpression of miR-30d during liver cancer progression in rats
Published 2017-04-01“…The identification of molecules that might be molecular markers or therapeutic targets is urgently needed to improve clinical management. Based on a microarray analysis performed in our laboratory, we selected six genes—namely, ANXA2, DYNLT1, PFKP, PLA2G7, KRT19 , and SNX10 —as candidates for validation as tumor markers of liver cancer in a rat model. …”
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340
SPP1 mRNA Expression Is Associated with M2 Macrophage Infiltration and Poor Prognosis in Triple-Negative Breast Cancer
Published 2024-11-01“…Additionally, we examined SPP1 mRNA expression datasets available in the Kaplan–Meier plotter and investigated the SPP1 protein expression patterns in our own tissue microarray cohort via immunohistochemistry. (3): The results revealed that genes associated with the Toll-like receptor signaling pathway showed a significant increase in activity in TNBC tissues when compared to normal breast tissues. …”
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