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421
Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment.
Published 2025-01-01“…<h4>Results</h4>Four AR signature genes (MRPS30, CLPX, MRPL13, and MRPL53) were selected by the MCC, EPC, BottleNeck, and Closeness algorithms. …”
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422
SMART: unique splitting-while-merging framework for gene clustering.
Published 2014-01-01“…Moreover, two real microarray gene expression datasets are studied using this approach. …”
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423
Bioinformatic-based differential expression gene expressions of epithelial mesenchymal transformation in diabetic kidney disease and prediction of traditional Chinese medicine
Published 2022-11-01“…ObjectiveBased upon the bioinformatic analysis of gene chip data between patients with diabetic kidney disease (DKD) and normal controls, differentially expressed genes of epithelial mesenchymal transformation of DKD were screened for elucidating its pathogenesis and predicting the potential therapeutic Chinese medicine for DKD.MethodsGSE23338 microarray data were downloaded from gene expression omnibus, related differentially expressed genes screened by R language and differentially expressed genes analyzed by Gene Ontology, Kyoto Encyclopedia of Genes and Genomes. …”
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424
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…In our study, we analyzed RA microarray data from the Gene Expression Omnibus (GEO) and focused on cellular senescence genes from the CellAge database. …”
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425
Glucose-6-phosphate dehydrogenase activity, structure, molecular characteristics and role in neonatal hyperbilirubinemia in cord blood in Cukurova region
Published 2011-04-01“…These differences might be caused by the effects of kinetic variant on the hyperbilirubinemia without the direct effect of the mutation. …”
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426
Ultradian cortisol pulsatility encodes a distinct, biologically important signal.
Published 2011-01-01“…In addition, effects on glucocorticoid receptor (GR) expression levels and phosphorylation, as a potential mediator, were measured.…”
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427
Stabilization of Transcription Factor, HIF-1α by Prolylhydroxylase 1 Knockout Reduces Cardiac Injury After Myocardial Infarction in Mice
Published 2025-03-01“…Our current work investigates the protective effects of PHD1 knockout in mice against myocardial infarction. …”
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428
Exploration of autophagy-related molecular mechanisms underlying epilepsy using multiple datasets
Published 2025-08-01“…Methods We analyzed GSE143272 and GSE4290 microarray datasets from the NCBI Gene Expression Omnibus database, which is established based on evaluations of peripheral blood samples. …”
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429
Integrated Bioinformatics Analysis of Hub Genes and Pathways in Anaplastic Thyroid Carcinomas
Published 2019-01-01“…The aim of the present study was to identify hub genes and pathways in ATC by microarray expression profiling. Two independent datasets (GSE27155 and GSE53072) were downloaded from GEO database. …”
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430
Hub genes and associated drugs for multiple myeloma with 1q21+: identified by bioinformatic analysis
Published 2024-12-01“…While 1q21+ was common genetic alteration and found to have adverse effect on prognosis, the underlying genes remain unclear. …”
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431
Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathway.
Published 2014-01-01“…Recent evidence suggests that local anesthetics have a broad spectrum of effects including inhibition of cell proliferation and induction of apoptosis in neuronal and other types of cells. …”
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432
Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling.
Published 2007-11-01“…The chronic effects of cocaine abuse on brain structure and function are blamed for the inability of most addicts to remain abstinent. …”
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433
Parallel clustering algorithm for large-scale biological data sets.
Published 2014-01-01“…The runtime is reduced from serval hours to a few seconds, which indicates that parallel algorithm is capable of handling large-scale data sets effectively. The parallel affinity propagation also achieves a good performance when clustering large-scale gene data (microarray) and detecting families in large protein superfamilies.…”
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434
M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p
Published 2025-01-01“…The molecular mechanism was evaluated using microarray analysis, RT-qPCR, dual-luciferase reporter analysis, and RNA pull-down assay. …”
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435
Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems.
Published 2025-01-01“…RNA microarray was performed using HBV-infected PXB cells with STAT1 knockdown. …”
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436
Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study
Published 2024-01-01“…We explored the expression pattern and clinicopathological significance of ZIC2 in oral cancer through performing in-house tissue microarray and integrated analysis global RNA-seq and microarrays containing large samples. …”
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437
Transcription factor binding site analysis identifies FOXO transcription factors as regulators of the cutaneous wound healing process.
Published 2014-01-01“…The search for significantly overrepresented and co-occurring transcription factor binding sites in the promoter regions of the most differentially expressed genes in microarray data sets could be a powerful approach for finding key regulators of complex biological processes. …”
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438
Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.
Published 2014-01-01“…We found that COX-2 inhibition had no effect on CSC growth, or resistance to chemotherapy. …”
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439
Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant.
Published 2011-01-01“…We report here on the characterization of a synthetic hexaacylated lipid A derivative, denoted as glucopyranosyl lipid adjuvant (GLA). We assessed the effects of GLA on murine and human dendritic cells (DC) by combining microarray, mRNA and protein multiplex assays and flow cytometry analyses. …”
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440
A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development.
Published 2018-01-01“…Gene ontology analysis also suggested that some of the genes activated-by-JHA/repressed-by-JHD play roles in spermatogenesis. Affymetrix microarray-based analysis indicated that the expression of genes activated-by-JHA/repressed-by-JHD was testis-specific. …”
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