Genetic correlation between fetal nuchal translucency thickening and cystic hygroma and exploration of pregnancy outcome by Jianli Zheng, Tiantian Wang, Huilin Sun, Yongjuan Guan, Fangfang Yang, Jing Wu, Feifei Ying, Yadong Fu, Min Li, Jianbing Liu

“…Abstract Chromosome microarray analysis (CMA) and whole exome sequencing (WES) are increasingly utilized in prenatal diagnosis of abnormal ultrasound findings, but studies on correlation between pathogenic copy number variations (pCNVs) and single-gene mutations in fetuses with nuchal translucency (NT) thickening/cystic hygroma (CH), and pregnancy outcomes, are rare. …”
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Ultrasensitive Peptide-Based Electrochemical Biosensor for Universal Diagnostic of Dengue by Isis Campos Prado, João Pedro Rangel da Silva Carvalho, André Souza Araujo, Paloma Napoleão-Pêgo, Salvatore Giovanni De-Simone

“…An identified linear B-cell epitope (DENV/18) specific for DENV 1–4 serotypes recognized by IgG in patient sera was selected as a target molecule after a microarray of peptides using the SPOT-synthesis methodology. …”
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CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion by Hongbo Liu, Haoqi Wang, Wei Gao, Yang Yuan, Tiantian Tang, Meixiang Sang, Fei Liu, Cuizhi Geng

“…We found a novel circRNA named circATP5C1, whose function in TNBC remains uncovered. Tissue microarray was used to analyze the association between the expression of circATP5C1 and the prognoses of TNBC patients. …”
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Identifying 4 Novel lncRNAs as Potential Biomarkers for Acute Rejection and Graft Loss of Renal Allograft by Zedan Zhang, Yanlin Tang, Hongkai Zhuang, Enyu Lin, Lu Xie, Xiaoqiang Feng, Jiayi Zeng, Yanjun Liu, Jiumin Liu, Yuming Yu

“…Then, 4 optimal DElncRNAs, ATP1A1-AS1, CTD-3080P12.3, EMX2OS, and LINC00645, were selected from 17 prognostic DElncRNAs to establish the 4-lncRNA risk score model. …”
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Characterizing Methicillin-Resistant <i>Staphylococcus</i> spp. and Extended-Spectrum Cephalosporin-Resistant <i>Escherichia coli</i> in Cattle by Lisa Abdank, Igor Loncaric, Sascha D. Braun, Elke Müller, Stefan Monecke, Ralf Ehricht, Reinhild Krametter-Frötscher

“…Isolates were characterized by a polyphasic approach including susceptibility pheno- and genotyping and microarray-based assays. No methicillin-resistant <i>Staphylococcus aureus</i> was found in the milk samples, but one nasal swab was positive for methicillin-resistant <i>Staphylococcus aureus</i>. …”
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Establishment and Genetic Profiling of Platinum/Taxane Doublet-Resistant Cells Generated by Hybridizing Single Resistant Cells by Seiji Isonishi, Rika Saito, Noriko Yamaguchi, Saburo Saito

“…The resistant cells were selected through repeated exposure to cisplatin and paclitaxel. …”
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IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion by Madelene Lindkvist, Anna Göthlin Eremo, Geena Varghese Paramel, Sheikh Anisul Haque, Camilla Rydberg Millrud, Sara Rattik, Caitríona Grönberg, David Liberg, Allan Sirsjö, Karin Fransén

“…Background Blockade of IL1RAP (interleukin 1 receptor associated protein) was recently shown to reduce atherosclerosis in mice, but the effect on human vascular cells is largely unknown. …”
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Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation by Olof Gidlöf, Andrea L. Johnstone, Kerstin Bader, Bohdan B. Khomtchouk, Jiaqi J. O'Reilly, Selvi Celik, Derek J. Van Booven, Claes Wahlestedt, Bernhard Metzler, David Erlinge

“…The aim of this study was to investigate the effect of histone methylation in the response to cardiac ischemic preconditioning. …”
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Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…The expression of programmed cell death ligand 1 (PD-L1) largely determines the efficacy and effectiveness of cancer immunotherapies targeting this specific immune checkpoint. …”
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Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics... by Ziwei Gong, Rong Cao, Hong Zhu

“…In MS peripheral blood microarray data, CD40 is significantly downregulated in RRMS. …”
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GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer by Yongchang Zheng, Yue Shi, Si Yu, Yuanyuan Han, Kai Kang, Haifeng Xu, Huajian Gu, Xinting Sang, Yang Chen, Jingyu Wang

“…To investigate underlying molecular mechanism, we generated GTSE1 knockdown HCC cell line and explored the effects of GTSE1 deficiency in cell growth. Between GTSE1 knockdown and wild-type HCC cells, we identified 979 differentially expressed genes (520 downregulated and 459 upregulated genes) in the analysis of microarray-based gene expression profiling. …”
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Immunohistochemistry‐based molecular subtypes of urothelial carcinoma derive different survival benefit from platinum chemotherapy by Csilla Olah, Oleksandr Shmorhun, Gilbert Georg Klamminger, Josefine Rawitzer, Lara Sichward, Boris Hadaschik, Mulham Al‐Nader, Ulrich Krafft, Christian Niedworok, Melinda Váradi, Peter Nyirady, Andras Kiss, Eszter Szekely, Henning Reis, Tibor Szarvas

“…However, high tumor heterogeneity between the primary tumor and metastatic sites can impact the effectiveness of therapies.…”
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MicroRNA-26b inhibits cardiac remodeling after myocardial infarction by targeting ring finger protein 6 expression by Chun-Mei Tang, Qiang Su, Hai-Xia Zhao, He-Huan Sui, Jing Liang, Li-Sha Zhu, Si-Yun Yang, Tao Liu

“…Material and methods An MI rat model was established by left coronary artery ligation. Microarray data were analyzed to distinguish differentially expressed genes in MI. miR-26b was found to be poorly expressed, whereas ring finger protein 6 (RNF6) was highly expressed in MI. …”
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Assessment of NUDT5 in Endometrial Carcinoma: Functional Insights, Prognostic and Therapeutic Implications by Hongfei Yu, Lingling Zu, Yuqin Zang, Fei Teng, Tao Wang, Ming Wu, Yingmei Wang, Fengxia Xue

“…<b>Methods</b>: This study analyzed gene expression data from The Cancer Genome Atlas and performed tissue microarray validation to assess <i>NUDT5</i> expression in EC samples. …”
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Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma by Katherine J. Crawford, Kennedy S. Humphrey, Eduardo Cortes, Jianxin Wang, Vishnu Kumarasamy, Yin Wan, Mark D. Long, Michael E. Feigin, Agnieszka K. Witkiewicz, Karen M. Mann, Erik S. Knudsen, Ethan V. Abel

“…Single-cell RNA sequencing (scRNA-seq), tissue microarray (TMA) data, and UMAP spatial profiling were used to identify FGFR4 as an HNF1A target gene upregulated in metastatic cells. …”
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Highly proliferating cancer cells function as novel prognostic biomarkers for lung adenocarcinoma with particular usefulness for stage IA risk stratification by Yanlu Xiong, Yongfu Ma, Jie Lei, Jianfei Zhu, Nianlin Xie, Feng Tian, Qiang Lu, Miaomiao Wen, Qian Zheng, Yong Han, Tao Jiang, Yang Liu

“…Next, we analysed the OS predictive effect of HPCs at different LUAD stages, especially for stage I risk stratification. …”
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miR-21-5p Enriched Exosomes from Human Embryonic Stem Cells Promote Osteogenesis via YAP1 Modulation by Huang X, Zhao Z, Zhan W, Deng M, Wu X, Chen Z, Xie J, Ye W, Zhao M, Chu J

“…Xinqia Huang,1,&ast; Ziquan Zhao,1,&ast; Weiqiang Zhan,1 Mingzhu Deng,1 Xuyang Wu,1 Zhoutao Chen,1 Jiahao Xie,2 Wei Ye,3 Mingyan Zhao,1,4 Jiaqi Chu3,4 1Orthopaedic Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China; 2Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China; 3Department of Obstetrics and Gynecology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China; 4Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jiaqi Chu; Mingyan Zhao, Affiliated Hospital of Guangdong Medical University, No. 57 Renmin Avenue South Road, Zhanjiang, Guangdong, 524001, People’s Republic of China, Email chujiaqi@gdmu.edu.cn; mingyan.zhao@gdmu.edu.cnPurpose: To investigate the osteogenic potential of human embryonic stem cell-derived exosomes (hESC-Exos) and their effects on the differentiation of human umbilical cord mesenchymal stem cells (hUCMSCs).Methods: hESC-Exos were isolated and characterized using transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA), and Western blotting. hUCMSCs were cultured with hESC-Exos to assess osteogenic differentiation through alizarin red staining, quantitative PCR (qPCR), and Western blotting. miRNA profiling of hESC-Exos was performed using miRNA microarray analysis. …”
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Spatially resolved analysis of TGF/BMP signalling in pancreatic ductal adenocarcinoma by digital pathology identifies patient subgroups with adverse outcome by Konstantin Bräutigam, Philipp Zens, Stefan Reinhard, Jessica L. Rohrbach, Simon J. Leedham, Anna S. Wenning, Beat Gloor, Viktor H. Koelzer, Martin Wartenberg

“…Methods We performed a spatially resolved analysis of PDAC on a multi-region tissue microarray cohort of 117 curatively resected PDAC specimens consisting of tumour centre (TC), tumour front (TF), and stromal(-predominant) tissue cores each. …”
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Expression, clinical significance and biological function of CDC7 in osteosarcoma by CHEN Peijun, MAN Yunan, HE Mingwei, LIANG Bumin, HE Maolin

“…Methods The mRNA microarray data from the Gene Expression Omnibus (GEO) database was used to analyze the expression of CDC7 in OS tissues. …”
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Hypoxia‐induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9‐mediated GSK3β/β‐catenin signalling by Jia‐cheng Xu, Lin‐feng Wu, Tian‐yin Chen, Yan‐bo Liu, Yi‐fei Zhang, Ping‐hong Zhou, Yi‐qun Zhang

“…Methods Esophageal cancer bioinformatics analysis and tissue microarray analysis were employed to elucidate the aberrant expression of PGK1 during ESCC progression. …”
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