The microRNA expression signature of CD4+ T cells in the transition of brucellosis into chronicity. by Ferah Budak, Salih Haldun Bal, Gulcin Tezcan, Emin Halis Akalın, Abdullah Yılmaz, Pınar Hız, Haluk Barbaros Oral

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Is cardiovascular risk profiling from UK Biobank retinal images using explicit deep learning estimates of traditional risk factors equivalent to actual risk measurements? A prospec... by Kohji Nishida, Ryo Kawasaki, Yiming Qian, Liangzhi Li, Yuta Nakashima, Hajime Nagahara

“…This two-stage approach provides human interpretable information between stages, which helps clinicians gain insights into the screening process copiloting with the DL model.…”
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Machine learning and SHAP value interpretation for predicting the response to neoadjuvant chemotherapy and long-term clinical outcomes in Chinese female breast cancer by Quan Yuan, Rongjie Ye, Yao Qian, Hao Yu, Yuexin Zhou, Xiaoqiao Cui, Feng Liu, Ming Niu

“…The Least Absolute Shrinkage and Selection Operator (LASSO) Cox algorithm, combined with XGBoost and Random Forest (RF) models, identified 9 overlapping prognostic features, enhancing the nomogram’s predictive accuracy for overall survival (OS). …”
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An Upper Partial Moment Framework for Pathfinding Problem Under Travel Time Uncertainty by Xu Zhang, Mei Chen

“…Theoretical analysis shows that the MUPM framework is consistent with the expected utility theory (EUT) and stochastic dominance theory (SDT), providing a behavioral foundation for the model. To efficiently solve the model, an SDT-based label-correcting algorithm is adapted, with a pre-screening step to reduce unnecessary pairwise path comparisons. …”
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Global trends in machine learning applications for single-cell transcriptomics research by Xinyu Liu, Zhen Zhang, Chao Tan, Yinquan Ai, Hao Liu, Yuan Li, Jin Yang, Yongyan Song

“…Research hotspots concentrated on random forest (RF) and deep learning models, showing transition from algorithm development to clinical applications (e.g., tumor immune microenvironment analysis). …”
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Predicting diabetic peripheral neuropathy through advanced plantar pressure analysis: a machine learning approach by Mehewish Musheer Sheikh, Mamatha Balachandra, Narendra V. G., Arun G. Maiya

“…An automated image processing algorithm segmented plantar pressure images into forefoot and hindfoot regions for precise pressure distribution measurement. …”
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An Automatic Measurement Method of Test Beam Response Based on Spliced Images by Dong Liang, Jing Liu, Lida Wang, Chenjing Liu, Jia Liu

“…Next, the spliced image is obtained through the PCA-SIFT method with a screening mechanism. The cracks’ information is acquired by the dual network model. …”
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Health inequities in medical crowdfunding: a systematic review by Yingying Cai, Syafila Kamarudin, Xiaoyu Jiang, Baiyu Zhou

“…In regions with high medical debt or limited insurance coverage, more crowdfunding campaigns appeared, but with lower overall success. …”
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Shared and Distinctive Inflammation-Related Protein Profiling in Idiopathic Inflammatory Myopathy with/without Anti-MDA5 Autoantibodies by Zhang Y, Hu W, Li T, Pan Z, Sun J, He Y, Guan W, Zhang L, Lian C, Liu S, Zhang P

“…The least absolute shrinkage and selection operator (Lasso) regression algorithm of machine learning was used to screen biomarkers related to anti-MDA5+ DM.Results: Compared with HCs, 36 inflammation-related proteins were identified as DEPs. …”
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Diagnostic Value of F-FDG PET/CT Radiomics in Lymphoma: A Systematic Review and Meta-Analysis by Chaoying Liu MD, Jun Zhao PhD, Heng Zhang PhD, Xinye Ni PhD

“…Six meta-regressions were conducted on study performance, considering sample size, image modality, region of interest (ROI) selection, ROI segmentation, radiomics mode, and algorithms. Results In total, 20 studies classified as type 2a or above according to the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement were included for this systematic review and meta-analysis. …”
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Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning by Sizhang Wang, Xiaoyan Wang, Jing Xia, Qiang Mu

“…Then, four overlapping M1 macrophage infiltration-related genes (M1 MIRGs), namely CCDC69, PPP1R16B, IL21R, and FOXP3, were obtained using five machine-learning algorithms. Subsequently, nomogram models were constructed to predict the incidence of Her2-positive breast cancer patients. …”
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A scoping review on metrics to quantify reproducibility: a multitude of questions leads to a multitude of metrics by Rachel Heyard, Samuel Pawel, Joris Frese, Bernhard Voelkl, Hanno Würbel, Sarah McCann, Leonhard Held, Kimberley E. Wever, Helena Hartmann, Louise Townsin, Stephanie Zellers

“…The metrics were characterized based on type (formulas and/or statistical models, frameworks, graphical representations, studies and questionnaires, algorithms), input required and appropriate application scenarios. …”
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Immunoglobulin G N-Glycosylation and Inflammatory Factors: Analysis of Biomarkers for the Diagnosis of Moyamoya Disease by Zan X, Liu C, Wang X, Sun S, Li Z, Zhang W, Sun T, Hao J, Zhang L

“…This research aimed to evaluate the diagnostic efficacy of IgG N-glycosylation for MMD.Methods: Ultra-high-performance liquid chromatography (UPLC) was employed to examine the properties of IgG N-glycans in blood samples from 116 patients with MMD and 126 controls, resulting in the quantitative determination of 24 initial glycan peaks (GP). Through the Lasso algorithm and multivariate logistic regression analysis, we constructed a diagnostic model based on initial glycans and related inflammatory factors to distinguish MMD patients from healthy individuals.Results: After adjusting for potential confounding variables, including age, fasting blood glucose (FBG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), neutrophil count (NEUT), and lymphocyte count (LYM), our study demonstrated significant differences in the characteristics of 6 initial glycans and 16 derived glycans between the MMD cohort and the healthy control group. …”
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Leveraging diverse cell-death patterns to predict to predict prognosis and immunotherapy in hepatocellular carcinoma by Xiaoxiang Zhang, Dongxiao Ding, Dianqian Wang, Yunsheng Qin

“…Although many efforts have been made to improve the prognosis of LIHC, the situation is still dismal. …”
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Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer by Wang S, Ma C, Ren Z, Zhang Y, Hao K, Liu C, Xu L, He S, Zhang J

“…The signatures were screened in a discovery cohort of GC patients (n=55) and non-disease controls (n=46) using an integrated process, including high-throughput sequencing technology, screening using a complete bioinformatics algorithm, validation using RT-qPCR, and evaluation by constructing a diagnostic model. …”
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Research on Path Optimization of Vehicle-Drone Joint Distribution considering Customer Priority by Xiaoye Zhou, Yuhao Feng

“…Compared with the three algorithms and error analysis, the effectiveness of the model and the two-stage algorithm was verified. …”
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Optimization of the Canopy Three-Dimensional Reconstruction Method for Intercropped Soybeans and Early Yield Prediction by Xiuni Li, Menggen Chen, Shuyuan He, Xiangyao Xu, Panxia Shao, Yahan Su, Lingxiao He, Jia Qiao, Mei Xu, Yao Zhao, Wenyu Yang, Wouter H. Maes, Weiguo Liu

“…Point cloud preprocessing was refined through the application of secondary transformation matrices, color thresholding, statistical filtering, and scaling. Key algorithms—including the convex hull algorithm, voxel method, and 3D α-shape algorithm—were optimized using MATLAB, enabling the extraction of multi-dimensional canopy parameters. …”
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Dynamic SOFA component scores-based deep learning for short to long-term mortality prediction in sepsis survivors by Juan Wei, Feihong Lin, Tian Jin, Qian Yao, Sheng Wang, Di Feng, Xin Lv, Wen He

“…Comparisons were made with a multilayer perceptron and two machine learning models of random forest and eXtreme Gradient Boosting (XGBoost). …”
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Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medici... by Yuan S, Zhang R, Zhu Z, Zhou X, Zhang H, Li X, Hao Y

“…We applied metabolomics to identify differential metabolites distinguishing these patterns.Methods: In this study, the first principal component was analyzed by the OPLS-DA model. The model quality was evaluated by 7-fold cross-validation, and the model validity was evaluated based on R²Y (interpretability of categorical variable Y) and Q² (predictability of the model), and the permutation test was used for further verification. …”
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Integrative machine learning and molecular simulation approaches identify GSK3β inhibitors for neurodegenerative disease therapy by Hassan H. Alhassan

“…Among all models, the Random Forest (RF) algorithm had the best prediction accuracy, with a value of 0.6832 on the test set and 0.7432 on the training set, and was employed to screen the target library of 11,032 phytochemicals. …”
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