-
881
Gas adsorption meets geometric deep learning: points, set and match
Published 2024-11-01“…Recently, machine learning (ML) pipelines have been established as the go-to method for large scale screening by means of predictive models. These are typically built in a descriptor-based manner, meaning that the structure must be first coarse-grained into a 1D fingerprint before it is fed to the ML algorithm. …”
Get full text
Article -
882
Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery
Published 2025-07-01“…Subsequently, we performed Gene Ontology (GO) analysis and Kyoto encyclopedia of genes and genomes (KEGG) analyses, followed by immune infiltration analysis using the single-sample gene-set enrichment analysis (ssGSEA) and CIBERSORT algorithms. By constructing a multivariate Cox prognostic model using Kaplan–Meier curves and least absolute shrinkage and selection operator (LASSO) regression analysis, we assessed the model’s prognostic capability. …”
Get full text
Article -
883
Integrated analysis of single-cell RNA-seq and spatial transcriptomics to identify the lactylation-related protein TUBB2A as a potential biomarker for glioblastoma in cancer cells...
Published 2025-06-01“…Notably, the expression levels of these three hub genes and the lactylation level of TUBB2A in GBM tissues were significantly higher compared to those in normal tissues.ConclusionsWe propose and validate a IQR lactylation screening method that provides potential insights for GBM therapy and an effective framework for developing gene screening models applicable to other diseases and pathogenic mechanisms.…”
Get full text
Article -
884
Bioinformatics analysis of potential targets influencing the prognosis of OSCC
Published 2024-06-01“…The Timer website was used to analyze the relationship between hub genes and immune cell infiltration and immune checkpoints. Based on Lasso-Cox algorithm, a prognostic risk model of related genes was constructed. …”
Get full text
Article -
885
Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics
Published 2025-02-01“…The diagnostic performance was assessed by supplementing external datasets to draw ROC curves on the diagnostic model. The diagnostic model was further screened for key genes by prognostic analysis. …”
Get full text
Article -
886
Technical Code Analysis of Geomagnetic Flaw Detection of Suppression Rigging Defect Signal Based on Convolutional Neural Network
Published 2024-12-01“…The single-stage object detection algorithm YOLOv5 (You Only Look Once) based on convolutional neural network model calculation is used, the scale detection layer and positioning loss function of the YOLOv5 algorithm are improved and optimized, and the improved YOLOv5 algorithm is used for experiments. …”
Get full text
Article -
887
Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for thyroid cancer
Published 2025-06-01“…Abstract Background Thyroid cancer (THCA) exhibits high molecular heterogeneity, posing challenges for precise prognosis and personalized therapy. Most existing models rely on single-omics data and limited algorithms, reducing robustness and clinical value. …”
Get full text
Article -
888
The value of habitat analysis based on 18F-PSMA-1007 PET/CT images for prostate cancer risk grading
Published 2025-07-01“…Independent risk factors were screened and a combined model was constructed to predict GS grade by univariate logistic regression followed by multivariate logistic regression of habitat (1–4) and clinical factors (SUVmax, tPSA, fPSA/tPSA, age). …”
Get full text
Article -
889
Machine Learning and Deep Learning Techniques for Prediction and Diagnosis of Leptospirosis: Systematic Literature Review
Published 2025-05-01“…MethodsUsing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies (CHARMS), and Prediction model Risk of Bias Assessment Tool (PROBAST) tools, we conducted a comprehensive review of studies applying ML and DL models for leptospirosis detection and prediction, examining algorithm performance, data sources, and validation approaches. …”
Get full text
Article -
890
3D Film Animation Image Acquisition and Feature Processing Based on the Latest Virtual Reconstruction Technology
Published 2021-01-01“…Finally, the target 3D face is reconstructed using the feature points of the target face for model matching. The experimental results show that the algorithm reconstructs faces with high realism and accuracy, and the algorithm can reconstruct expression faces.…”
Get full text
Article -
891
High‐resolution mapping of cancer cell networks using co‐functional interactions
Published 2018-12-01“…This work establishes new algorithms for probing cancer cell networks and motivates the acquisition of further CRISPR screen data across diverse genotypes and cell types to further resolve complex cellular processes.…”
Get full text
Article -
892
An estimation method of lightning-voltage sag severity based on adaptive association rule mining
Published 2025-07-01“…The key condition attributes that affect voltage sag severity are screened by attribute reduction algorithm. An association rule mining algorithm based on parameter adaption is proposed, which overcomes the problem that the results of traditional association rules mining methods are affected by non-uniform data. …”
Get full text
Article -
893
Predicting radiation pneumonitis in lung cancer using machine learning and multimodal features: a systematic review and meta-analysis of diagnostic accuracy
Published 2024-11-01“…By selecting multiple machine learning algorithm frameworks and competing for the best combination model based on research goals, the reliability and accuracy of the radiation pneumonitis prediction model can be greatly improved. …”
Get full text
Article -
894
Increasing comprehensiveness and reducing workload in a systematic review of complex interventions using automated machine learning
Published 2022-11-01“…Background As part of our ongoing systematic review of complex interventions for the primary prevention of cardiovascular diseases, we have developed and evaluated automated machine-learning classifiers for title and abstract screening. The aim was to develop a high-performing algorithm comparable to human screening. …”
Get full text
Article -
895
Intratumoral and peritumoral CT radiomics in predicting anaplastic lymphoma kinase mutations and survival in patients with lung adenocarcinoma: a multicenter study
Published 2025-03-01“…The GPTV3 radiomics model using a support vector machine algorithm achieved the best predictive performance, with the highest average AUC of 0.811 in the validation sets. …”
Get full text
Article -
896
Role of arachidonic acid metabolism in osteosarcoma prognosis by integrating WGCNA and bioinformatics analysis
Published 2025-03-01“…An AA metabolism predictive model of the five AAMRGs were established by Cox regression and the LASSO algorithm. …”
Get full text
Article -
897
Global trends in machine learning applications for single-cell transcriptomics research
Published 2025-08-01“…Research hotspots concentrated on random forest (RF) and deep learning models, showing transition from algorithm development to clinical applications (e.g., tumor immune microenvironment analysis). …”
Get full text
Article -
898
The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway
Published 2025-04-01“…Finally, potential clinical drugs targeting CD163 + macrophages with high ferroptosis activity in TAO were predicted using the Random Walk with Restart (RWR) algorithm combined with the DGIdb database. Results We first utilized TAO-related datasets from the GEO database, combined with the FerrDb ferroptosis database, to identify changes in iron metabolism genes during TAO progression through differential expression analysis, screening 7 key ferroptosis-related proteins. …”
Get full text
Article -
899
Enhancing glaucoma diagnosis: Generative adversarial networks in synthesized imagery and classification with pretrained MobileNetV2
Published 2025-06-01“…This approach does not only contribute to glaucoma screening but also can also reveal the benefits of the GANs and transfer learning in medical imaging. • A GAN approach to generate high-quality fundus image datasets in an attempt to minimize dataset differences. • Implemented improved Enhanced Level Set Algorithm for Optic Cup segmentation. • Built on top of the pretrained MobileNetV2 to obtain better results of glaucoma classification.…”
Get full text
Article -
900
Time-Distributed Vision Transformer Stacked With Transformer for Heart Failure Detection Based on Echocardiography Video
Published 2024-01-01“…This study proposed a novel deep learning model consisting of a time-distributed vision transformer stacked with a transformer. …”
Get full text
Article