Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers by Hengyan Zhang, Ye Zhou, Heguo Yan, Changxing Huang, Licong Yang, Yangwen Liu

“…We integrated the genes screened by three machine learning models (LASSO, SVM, and Random Forest), and CXCR4 was identified as a key gene with potential therapeutic value in DFUs. …”
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Integrating digital and narrative medicine in modern healthcare: a systematic review by Efthymia Efthymiou

“…The increasing integration of digital technologies in healthcare, such as electronic health records, telemedicine, and diagnostic algorithms, improved efficiency but raised concerns about the depersonalization of care. …”
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Exploring the predictive values of CRP and lymphocytes in coronary artery disease based on a machine learning and Mendelian randomization by Yuan Liu, Yuan Liu, Xin Yuan, Xin Yuan, Yu-Chan He, Yu-Chan He, Zhong-Hai Bi, Zhong-Hai Bi, Si-Yao Li, Si-Yao Li, Ye Li, Ye Li, Yan-Li Liu, Yan-Li Liu, Liu Miao, Liu Miao

“…Techniques employed included propensity score matching (PSM), logistic regression, lasso regression, and random forest algorithms (RF). Risk factors were assessed, and the sensitivity and specificity of the models were evaluated using receiver operating characteristic (ROC) curves. …”
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Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation by Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

“…Among the best-performing models with the least sensor data requirement, the ML algorithm predicted depressive symptoms with an accuracy of 80.6% (F1-score=0.76), high global MS symptom burden with an accuracy of 77.3% (F1-score=0.78), severe fatigue with an accuracy of 73.8% (F1-score=0.74), and poor sleep quality with an accuracy of 72.0% (F1-score=0.70). …”
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Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study by Duvern Ramiah, Sonwabile Ngcezu, Oluwatosin Ayeni, Okechinyere Achilonu, Mariam Adeleke, Theo Nair, Joseph Otten, Daniel Mmereki

“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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Unlocking autism’s complexity: the Move Initiative’s path to comprehensive motor function analysis by Ashley Priscilla Good, Elizabeth Horn

“…Move will make motor screenings more dynamic and longitudinal while supporting continuous assessment of targeted interventions. …”
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Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning by Sizhang Wang, Xiaoyan Wang, Jing Xia, Qiang Mu

“…Then, four overlapping M1 macrophage infiltration-related genes (M1 MIRGs), namely CCDC69, PPP1R16B, IL21R, and FOXP3, were obtained using five machine-learning algorithms. Subsequently, nomogram models were constructed to predict the incidence of Her2-positive breast cancer patients. …”
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Schizophrenia Detection and Classification: A Systematic Review of the Last Decade by Arghyasree Saha, Seungmin Park, Zong Woo Geem, Pawan Kumar Singh

“…Additionally, the analysis underscores common challenges, including dataset limitations, variability in preprocessing approaches, and the need for more interpretable models. Conclusions: This study provides a comprehensive evaluation of AI-based methods in SZ prognosis, emphasizing the strengths and limitations of current approaches. …”
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Disentangling High-Paced Alternating I/O in Gaze-Based Interaction by Yulia G. Shevtsova, Artem S. Yashin, Sergei L. Shishkin, Anatoly N. Vasilyev

“…The two functions can be easily separated in some tasks, like eye typing, but more complex scenarios typically require users to perform additional actions to avoid misinterpreting their intent. …”
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Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases. by Hang Su, Na Rei, Lei Zhang, Jiaxiang Cheng

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Epidemiology and Association Rules Analysis for Pulmonary Tuberculosis Cases with Extrapulmonary Tuberculosis from Age and Gender Perspective: A Large-Scale Retrospective Multicent... by Wanli Kang, Jiajia Yu, Chen Liang, Quanhong Wang, Liang Li, Jian Du, Hongyan Chen, Jianxiong Liu, Jinshan Ma, Mingwu Li, Jingmin Qin, Wei Shu, Peilan Zong, Yi Zhang, Xiaofeng Yan, Zhiyi Yang, Zaoxian Mei, Qunyi Deng, Pu Wang, Wenge Han, Meiying Wu, Ling Chen, Xinguo Zhao, Lei Tan, Fujian Li, Chao Zheng, Hongwei Liu, Xinjie Li, Ertai A., Yingrong Du, Fenglin Liu, Wenyu Cui, Song Yang, Xiaohong Chen, Junfeng Han, Qingyao Xie, Yanmei Feng, Wenyu Liu, Peijun Tang, Jianyong Zhang, Jian Zheng, Dawei Chen, Xiangyang Yao, Tong Ren, Yan Li, Yuanyuan Li, Lei Wu, Qiang Song, Mei Yang, Jian Zhang, Yuanyuan Liu, Shuliang Guo, Kun Yan, Xinghua Shen, Dan Lei, Yanli Zhang, Youcai Li, Yongkang Dong, Shenjie Tang

“…The multivariable logistic regression models demonstrated that odds ratios of concurrent PTB-EPTB cases varied by gender and age group. …”
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A scoping review on metrics to quantify reproducibility: a multitude of questions leads to a multitude of metrics by Rachel Heyard, Samuel Pawel, Joris Frese, Bernhard Voelkl, Hanno Würbel, Sarah McCann, Leonhard Held, Kimberley E. Wever, Helena Hartmann, Louise Townsin, Stephanie Zellers

“…The metrics were characterized based on type (formulas and/or statistical models, frameworks, graphical representations, studies and questionnaires, algorithms), input required and appropriate application scenarios. …”
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Forward first: Joystick interactions of toddlers during digital play. by Kimberly A Ingraham, Heather A Feldner, Katherine M Steele

“…These findings inform the design of assistive algorithms for joystick-enabled computer play and developmentally appropriate technologies for toddlers.…”
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Computer-assisted analysis of routine EEG to identify hidden biomarkers of epilepsy: A systematic review by Émile Lemoine, Joel Neves Briard, Bastien Rioux, Oumayma Gharbi, Renata Podbielski, Bénédicte Nauche, Denahin Toffa, Mark Keezer, Frédéric Lesage, Dang K. Nguyen, Elie Bou Assi

“…The computed biomarkers were based on linear (43%), non-linear (27%), connectivity (38%), and convolutional neural networks (10%) models. The risk of bias was high or unclear in all studies, more commonly from spectrum effect and data leakage. …”
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Multi-Omics Identification of <i>Fos</i> as a Central Regulator in Skeletal Muscle Adaptation to Long-Term Aerobic Exercise by Chaoyang Li, Xinyuan Zhu, Yi Yan

“…Key feature genes were screened using Lasso regression, SVM-RFE, and Random Forest machine learning algorithms, validated by RT-qPCR, and refined through PPI network analysis. …”
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Validating the recording of exacerbations of asthma in electronic health records: a systematic review protocol by Jennifer K Quint, Elizabeth Moore, Zakariah Z Gassasse

“…However, previous studies found significant heterogeneity in the algorithms used to define asthma exacerbations. Validating definitions of asthma exacerbations in EHR will lead to more robust and comparable evidence in future research.Methods and analysis Medline and Embase will be searched for the key concepts relating to asthma exacerbations, EHR and validation. …”
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Prediction of traditional Chinese medicine for diabetes based on the multi-source ensemble method by Bin Yang, Qingyun Chi, Xiang Li, Jinglong Wang

“…The compound dataset from the TCMSP database is then used as testing data to predict and screen the active ingredients. The frequencies of occurrences of medicinal herbs corresponding to these three algorithms are obtained, each containing an active ingredient list. …”
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Identification for internal reference genes in different periods of granulosa cells of Tianfu meat geese by MO Yuanliang, WANG Yushi, WANG Jiwen

“…Therefore, the most stable internal reference genes were SDH and HMBS in granulosa cells at different developmental stages, and it could get more accurate normalization of RT-qPCR data by geometric averaging of the most stable reference genes.…”
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A Line Feature-Based Rotation Invariant Method for Pre- and Post-Damage Remote Sensing Image Registration by Yalun Zhao, Derong Chen, Jiulu Gong

“…First, we extract and screen straight line segments from the images before and after damage. …”
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Health inequities in medical crowdfunding: a systematic review by Yingying Cai, Syafila Kamarudin, Xiaoyu Jiang, Baiyu Zhou

“…In regions with high medical debt or limited insurance coverage, more crowdfunding campaigns appeared, but with lower overall success. …”
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