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Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus
Published 2025-07-01“…Concurrently, gene expression datasets from GEO (POAG: GSE27276; COVID-19: GSE171110, GSE152418) were used to identify 57 crosstalk genes (CGs) via differential expression analysis. Machine learning algorithms (LASSO, SVM-RFE, Random Forest) were applied to screen POAG diagnostic biomarkers from CGs, followed by construction of transcription factor (TF)-microRNA (miRNA)-protein-compound regulatory networks and consensus clustering to characterize COVID-19 immune microenvironment subtypes. …”
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1222
Helicobacter pylori eradication treatment for gastric carcinoma prevention in asymptomatic or dyspeptic adults: systematic review and Bayesian meta-analysis of randomised controlle...
Published 2019-09-01“…However, concerns about supporting unfocused screening and eradication programme in healthy, asymptomatic populations have arisen. …”
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1223
The Role of AI in Nursing Education and Practice: Umbrella Review
Published 2025-04-01“…First, ethical and social implications were consistently highlighted, with studies emphasizing concerns about data privacy, algorithmic bias, transparency, accountability, and the necessity for equitable access to AI technologies. …”
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1224
Advancing Mn-based electrocatalysts: Evolving from Mn-centered octahedral entities to bulk forms
Published 2025-07-01“…According to the catalytic requirements of an individual entity and its stacking modes, we further developed a search algorithm to identify three-dimensional (3D) structures from 154,718 candidates, pinpointing CaMnO3 as the most effective one among the screened candidates. …”
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1225
Use of artificial intelligence to support prehospital traumatic injury care: A scoping review
Published 2024-10-01“…Conclusions A small but growing body of literature described AI models based on prehospital features that may support decisions made by dispatchers, Emergency Medical Services clinicians, and trauma teams in early traumatic injury care.…”
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1226
Optimization of Flavor Quality of Lactic Acid Bacteria Fermented Pomegranate Juice Based on Machine Learning
Published 2025-08-01“…There were 19 key differential volatile compounds screened out by ML. Binary classification models of HWPS and LWPS were established by random forest (RF) and adaptive boosting (AdaBoost) algorithms, and RF algorithm had higher prediction precision and accuracy. …”
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1227
Purine metabolism-associated key genes depict the immune landscape in gout patients
Published 2025-02-01“…Using RNA-seq data of peripheral blood mononuclear cells (PBMCs) from gout patients, we screened the differentially expressed genes (DEGs) of gout patients and found that they were closely involved in purine metabolism. …”
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1228
人工智能融合临床与多组学数据在卒中防治及医药研发中的应用与挑战Applications and Challenges of Integrating Artificial Intelligence with Clinical and Multi-omics Data in Stroke Prevention, Treatment, and Pharmaceut...
Published 2025-06-01“…By integrating and analyzing clinical and multi-omics data, AI technology enhances the identification of high-risk populations, optimizes early diagnosis and risk assessment, enables precise subtyping of stroke, facilitates the screening of potential drug targets, and constructs prognostic prediction models. …”
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1229
Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
Published 2025-02-01“…We integrated the genes screened by three machine learning models (LASSO, SVM, and Random Forest), and CXCR4 was identified as a key gene with potential therapeutic value in DFUs. …”
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1230
Project quality, regulation quality
Published 2024-06-01“…These tools legitimise choices where conformity to the standard acts as a screen for the assumption of precise responsibilities. …”
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1231
Exploring the predictive values of CRP and lymphocytes in coronary artery disease based on a machine learning and Mendelian randomization
Published 2024-09-01“…Techniques employed included propensity score matching (PSM), logistic regression, lasso regression, and random forest algorithms (RF). Risk factors were assessed, and the sensitivity and specificity of the models were evaluated using receiver operating characteristic (ROC) curves. …”
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1232
Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation
Published 2025-06-01“…Among the best-performing models with the least sensor data requirement, the ML algorithm predicted depressive symptoms with an accuracy of 80.6% (F1-score=0.76), high global MS symptom burden with an accuracy of 77.3% (F1-score=0.78), severe fatigue with an accuracy of 73.8% (F1-score=0.74), and poor sleep quality with an accuracy of 72.0% (F1-score=0.70). …”
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1233
Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study
Published 2025-07-01“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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1234
Lessons from the PROTECT-CH COVID-19 platform trial in care homes
Published 2025-04-01“…Results We initiated the trial including protocol, approvals, insurance, website, database, data algorithms, intervention selection and training materials. …”
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1235
Design, Fabrication, and Application of Large-Area Flexible Pressure and Strain Sensor Arrays: A Review
Published 2025-03-01“…The rapid development of flexible sensor technology has made flexible sensor arrays a key research area in various applications due to their exceptional flexibility, wearability, and large-area-sensing capabilities. …”
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1236
Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases.
Published 2018-01-01Get full text
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1237
Epidemiology and Association Rules Analysis for Pulmonary Tuberculosis Cases with Extrapulmonary Tuberculosis from Age and Gender Perspective: A Large-Scale Retrospective Multicent...
Published 2023-01-01“…The multivariable logistic regression models demonstrated that odds ratios of concurrent PTB-EPTB cases varied by gender and age group. …”
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INTERNATIONAL FORUM “OLD AND NEW MEDIA: ALONG THE PATH TOWARDS A NEW AESTHETICS” / МЕЖДУНАРОДНЫЙ ФОРУМ «СТАРЫЕ И НОВЫЕ МЕДИА: ПУТИ К НОВОЙ ЭСТЕТИКЕ»...
Published 2019-06-01“…Along with the formulation of the enumerated questions, the presentations of the participants of the conference concretized the conclusions about the influence of new media on the cognitive capabilities of man, his means of action, “new plasticity” and a new way of living. Notice was made of alarming tendencies of transforming consciousness into that of “gamers,” reacting in correlations with certain algorithms, and a transference from discourse and substantiations towards reactions and evaluations. …”
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Identification of biomarkers associated with inflammatory response in Parkinson's disease by bioinformatics and machine learning.
Published 2025-01-01“…LASSO, SVM-RFE and Random Forest algorithms were used to screen biomarker genes. Then, ROC curves were drawn and PD risk predicting models were constructed on the basis of the biomarker genes. …”
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Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning
Published 2025-04-01“…Then, four overlapping M1 macrophage infiltration-related genes (M1 MIRGs), namely CCDC69, PPP1R16B, IL21R, and FOXP3, were obtained using five machine-learning algorithms. Subsequently, nomogram models were constructed to predict the incidence of Her2-positive breast cancer patients. …”
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