Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Patients whose PCP was contacted were more likely to have adjustments made to their lipid lowering medication(s) (p = 0.016), be diagnosed with FH (p = 0.025), and have a follow-up visit (p = 0.033). …”
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Estimation of the aboveground carbon stocks based on tree species identification in Saihanba plantation forest by Ao Zhang, Xiaohong Wang, Xin Gu, Xiangyao Xu, Xintong Gao, Linlin Jiao

“…The results were shown that: 1) The identification effect of Scheme IV, as ascertained by screening three types of effective feature vectors based on the random forest algorithm, was the most effective, with an overall accuracy (OA) and kappa coefficient of 89.7% and 0.863, respectively. …”
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Cheetah optimized CNN: A bio-inspired neural network for automated diabetic retinopathy detection by V. K. U. Ahamed Gani, N. Shanmugasundaram

“…The proposed CO-CNN approach shows superior performance compared to that of state-of-the-art methods, offering potential applications in telemedicine, treatment planning, early detection, screening, and patient education. Integrating fuzzy logic enhances the model’s interpretability and robustness, paving the way for improved healthcare outcomes in diabetic retinopathy management.…”
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High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2... by Edelstein I.A., Gushchin A.E., Gladin D.P., Romanov A.V., Negasheva E.S., Frigo N.V., Kozlov R.S., Potekaev N.N., Kozlova N.S., Borukhovich D.G.

“…The most common combination of mutations was A2059G (23S rRNA) + S80I (parC), which made up to 33% (18/54) in St. Petersburg and 25.7% (25/97) in Moscow. …”
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New insights into biomarkers and risk stratification to predict hepatocellular cancer by Katrina Li, Brandon Mathew, Ethan Saldanha, Puja Ghosh, Adrian R. Krainer, Srinivasan Dasarathy, Hai Huang, Xiyan Xiang, Lopa Mishra

“…Abstract Hepatocellular carcinoma (HCC) is the third major cause of cancer death worldwide, with more than a doubling of incidence over the past two decades in the United States. …”
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Harnessing AI and Quantum Computing for Revolutionizing Drug Discovery and Approval Processes: Case Example for Collagen Toxicity by David Melvin Braga, Bharat Rawal

“…In this context, “in silico” describes scientific studies performed using computer algorithms, simulations, or digital models to analyze biological, chemical, or physical processes without the need for laboratory (in vitro) or live (in vivo) experiments. …”
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Project quality, regulation quality by Elena Mussinelli

“…These tools legitimise choices where conformity to the standard acts as a screen for the assumption of precise responsibilities. …”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2008 Update – Highlights for Primary Care by Denis E O’Donnell, Paul Hernandez, Alan Kaplan, Shawn Aaron, Jean Bourbeau, Darcy Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Yves Lacasse, Francois Maltais, Jeremy Road, Graeme Rocker, Don Sin, Tasmin Sinuff, Nha Voduc

“…Three key messages contained in the update are: use targeted screening spirometry to establish a diagnosis and initiate prompt management (including smoking cessation) of mild COPD; improve dyspnea and activity limitation in stable COPD using new evidence-based treatment algorithms; and understand the importance of preventing and managing acute exacerbations, particularly in moderate to severe disease.…”
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Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study by Olalekan A Uthman, Lena Al-Khudairy, Chidozie Nduka, Rachel Court, Jodie Enderby, Seun Anjorin, Hema Mistry, G J Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke

“…A machine learning study developed a parallel Convolutional Neural Network algorithm with 96.4% recall and 99.1% precision for study screening. …”
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Prevalence of tuberculosis, HIV and respiratory symptoms in two Zambian communities: implications for tuberculosis control in the era of HIV. by Helen Ayles, Albertus Schaap, Amos Nota, Charalambos Sismanidis, Ruth Tembwe, Petra De Haas, Monde Muyoyeta, Nulda Beyers, Peter Godfrey-Faussett for the ZAMSTAR Study Team

“…Epidemiological studies can inform screening algorithms for both detection and prevention of active tuberculosis.…”
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Robustness evaluation of commercial liveness detection platform by Pengcheng WANG, Haibin ZHENG, Jianfei ZOU, Ling PANG, Hu LI, Jinyin CHEN

“…Liveness detection technology has become an important application in daily life, and it is used in scenarios including mobile phone face unlock, face payment, and remote authentication.However, if attackers use fake video generation technology to generate realistic face-swapping videos to attack the living body detection system in the above scenarios, it will pose a huge threat to the security of these scenarios.Aiming at this problem, four state-of-the-art Deepfake technologies were used to generate a large number of face-changing pictures and videos as test samples, and use these samples to test the online API interfaces of commercial live detection platforms such as Baidu and Tencent.The test results show that the detection success rate of Deepfake images is generally very low by the major commercial live detection platforms currently used, and they are more sensitive to the quality of images, and the false detection rate of real images is also high.The main reason for the analysis may be that these platforms were mainly designed for traditional living detection attack methods such as printing photo attacks, screen remake attacks, and silicone mask attacks, and did not integrate advanced face-changing detection technology into their liveness detection.In the algorithm, these platforms cannot effectively deal with Deepfake attacks.Therefore, an integrated live detection method Integranet was proposed, which was obtained by integrating four detection algorithms for different image features.It could effectively detect traditional attack methods such as printed photos and screen remakes.It could also effectively detect against advanced Deepfake attacks.The detection effect of Integranet was verified on the test data set.The results show that the detection success rate of Deepfake images by proposed Integranet detection method is at least 35% higher than that of major commercial live detection platforms.…”
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Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. by Patrick Y Sips, Xu Shi, Gabriel Musso, Anjali K Nath, Yanbin Zhao, Jason Nielson, Jordan Morningstar, Amy E Kelly, Brittney Mikell, Eva Buys, Vikhyat Bebarta, Jared Rutter, V Jo Davisson, Sari Mahon, Matthew Brenner, Gerry R Boss, Randall T Peterson, Robert E Gerszten, Calum A MacRae

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Modified Diagnostic Criteria Tools for Familial Hypercholesterolemia without the Requirement for Clinical Genetic Testing: Rationale and Design of the MOOCS Adaptive Clinical Trial by Satyanarayana Upadhyayula

“…Various available FH diagnostic tools are grouped together in the FH diagnostic criteria tool universal algorithm. Background: The standard diagnostic criteria tools for FH require GT. …”
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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…We also wanted to know whether adding phone calls from a physiotherapist made the website more effective. Finally, we explored whether these options would represent ‘good value for money’ for the National Health Service. …”
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Cysticercosis in Madagascar by Jean-François Carod, Pierre Dorny

“…Neurocysticercosis (NCC) is the most common pattern of cysticercosis in Madagascar and it is reponsible for pediatric morbidity causing more than 50% of epilepsy cases. Though CT-Scan is now available and tends to be considered the gold standard for NCC diagnosis, it remains unaffordable for most Malagasy patients and implies the proposal of a diagnostic algorithm for physicians. …”
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Neurological post-COVID syndrome is associated with substantial impairment of verbal short-term and working memory by Jeyanthan Charles James, Hannah Schulze, Nadine Siems, Christian Prehn, Daniel R. Quast, Nadine Trampe, Ralf Gold, Simon Faissner

“…Neurologic PCS patients had more complaints with significantly higher fatigue scores as well as higher levels of depressive and anxiety symptoms compared to Non-PCS and HC. …”
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Research on predicting the risk level of coal mine roof accident based on machine learning by Zhao-Yang Guan, Jin-Ling Xie, Shen-Kuang Wu, Chao Liang

“…Finally, KNN, SVM and DT algorithms are used to evaluate the model performance. …”
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Neutrophil extracellular traps-related genes contribute to sepsis-associated acute kidney injury by Tang Shaoqun, Yu Xi, Wang Wei, Luo Yaru, Lei Shaoqing, Qiu Zhen, Yang Yanlin, Sun Qian, Xia Zhongyuan

“…Differentially expressed genes were screened by “limma” package in R. Least absolute shrinkage and selection operator algorithm was applied to identify the hub genes. …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…After univariate Cox analysis, prognostic genes were carried out for modeling mitochondria signature (MS) based on 101 combinations of 10 machine learning algorithms. …”
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Artificial intelligence-based automated breast ultrasound radiomics for breast tumor diagnosis and treatment: a narrative review by Yinglin Guo, Ning Li, Chonghui Song, Juan Yang, Yinglan Quan, Hongjiang Zhang

“…However, despite the notable performance and application potential of ML and DL models based on ABUS, the inherent variability in the analyzed data highlights the need for further evaluation of these models to ensure their reliability in clinical applications.…”
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