The use of heart rate variability, oxygen saturation, and anthropometric data with machine learning to predict the presence and severity of obstructive sleep apnea by Rafael Rodrigues dos Santos, Matheo Bellini Marumo, Alan Luiz Eckeli, Helio Cesar Salgado, Luiz Eduardo Virgílio Silva, Renato Tinós, Rubens Fazan

“…IntroductionObstructive sleep apnea (OSA) is a prevalent sleep disorder with a high rate of undiagnosed patients, primarily due to the complexity of its diagnosis made by polysomnography (PSG). Considering the severe comorbidities associated with OSA, especially in the cardiovascular system, the development of early screening tools for this disease is imperative. …”
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Prognostic Risk Signature and Comprehensive Analyses of Endoplasmic Reticulum Stress-Related Genes in Lung Adenocarcinoma by CaiZhen Yang, YuHui Wei, WenTao Li, JinMei Wei, GuoXing Chen, MingPeng Xu, GuangNan Liu

“…A total of 1034 samples from TCGA and GEO were used to screen differentially expressed genes. Further, Random Forest algorithm was utilized to screen characteristic genes related to prognosis. …”
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Machine learning based identification of anoikis related gene classification patterns and immunoinfiltration characteristics in diabetic nephropathy by Jing Zhang, Lulu Cheng, Shan Jiang, Duosheng Zhu

“…In addition, seven key genes, including PDK4, S100A8, HTRA1, CHI3L1, WT1, CDKN1B, and EGF, were screened by machine learning algorithm. Most of these genes exhibited low expression in renal tissue of DN patients and positive correlation with neutrophils, and their expressions were verified in an external dataset cell model. …”
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GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma by Hanxu Zhou, Zhi Chen, Shuang Gao, Chaoqun Lian, Junjie Hu, Jin Lu, Lei Zhang

“…We screened differential genes (DEGs) in the immune and stromal components, and then screened modular genes by the WGCNA algorithm, which were intersected with DEGs and incorporated into the LASSO-COX regression model. …”
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Research on the Evaluation of the Node Cities of China Railway Express Based on Machine Learning by Chenglin Ma, Mengwei Zhou, Wenchao Kang, Haolong Wang, Jiajia Feng

“…The Random Forest model outperformed comparative algorithms with 99.5% prediction accuracy (8.33% higher than conventional classification models), particularly in handling multi-dimensional interactions between urban development factors. …”
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Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes. by Taole Li, Jifeng Guo

“…According to the five machine algorithms, 4 features (S100A2, GNGT1, NEUROD4, FCN2) were screened and used to create a PD diagnostic model. …”
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Iterative phase contrast CT reconstruction with novel tomographic operator and data-driven prior. by Stefano van Gogh, Subhadip Mukherjee, Jinqiu Xu, Zhentian Wang, Michał Rawlik, Zsuzsanna Varga, Rima Alaifari, Carola-Bibiane Schönlieb, Marco Stampanoni

“…Moreover, the highly ill-conditioned differential nature of the GI-CT forward operator renders the inversion from corrupted data even more cumbersome. In this paper, we propose a novel regularized iterative reconstruction algorithm with an improved tomographic operator and a powerful data-driven regularizer to tackle this challenging inverse problem. …”
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Unveiling diagnostic biomarkers and therapeutic targets in lung adenocarcinoma using bioinformatics and experimental validation by Sixuan Wu, Yuanbin Tang, Qihong Pan, Yaqin Zheng, Yeru Tan, Junfan Pan, Yuehua Li

“…In addition, a machine learning model constructed based on Stepglm[backward] with the random forest algorithm achieved the highest C-index (0.999) and screened eight core genes, among which ST14 was noted for its excellent predictive ability. …”
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Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, a... by Guoqing Liu, Xiangwen Lv, Jiahui Qin, Xingqing Long, Miaomiao Zhu, Chuwen Fu, Jian Xie, Peichun He

“…Hub genes were screened using the least absolute shrinkage and selection operator (LASSO) and random forest (RF) algorithms. …”
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Utilizing Multi-omics analysis to elucidate the role of mitochondrial gene defects in Gastric cancer progression. by Jie Chu, Hanying Song, Kemin Fu, Wei Xiao, Jiudong Jiang, Qixin Gan, Bo Deng

“…Additionally, both the ssGSEA algorithm and the CIBERSORT algorithm were utilized to evaluate changes and effects in immunological characteristics during gastric cancer pathogenesis.…”
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WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer by Jing Lv, Jing Lv, Yuhua Zhou, Yuhua Zhou, Shengkai Jin, Shengkai Jin, Chaowei Fu, Chaowei Fu, Yang Shen, Yang Shen, Bo Liu, Bo Liu, Menglu Li, Yuwei Zhang, Yuwei Zhang, Ninghan Feng, Ninghan Feng, Ninghan Feng

“…Furthermore, a machine learning algorithm was used to screen for core genes and construct a diagnostic model, which was then validated in an external validation dataset. …”
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Integrating status-neutral and targeted HIV testing in Zimbabwe: A complementary strategy. by Hamufare D Mugauri, Owen Mugurungi, Joconiah Chirenda, Kudakwashe Takarinda, Prosper Mangwiro, Mufuta Tshimanga

“…First tests were 65% more likely to test HIV positive (a95%CI: 1.43, 1.91) whilst screened patients were 3.89 times more likely to link to HIV prevention services (a95%CI: 3.05, 4.97), against 25.5% (n = 1,871) linkage among patients not screened.…”
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InvarNet: Molecular property prediction via rotation invariant graph neural networks by Danyan Chen, Gaoxiang Duan, Dengbao Miao, Xiaoying Zheng, Yongxin Zhu

“…Predicting molecular properties is crucial in drug synthesis and screening, but traditional molecular dynamics methods are time-consuming and costly. …”
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Multi-Omics and Experimental Validation Identify GPX7 and Glutathione-Associated Oxidative Stress as Potential Biomarkers in Ischemic Stroke by Tianzhi Li, Sijie Zhang, Jinshan He, Hongyan Li, Jingsong Kang

“…Multidimensional feature screening using unsupervised consensus clustering and a series of machine learning algorithms led to the identification of the signature gene <i>GPX7</i>. …”
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Unveiling the ageing-related genes in diagnosing osteoarthritis with metabolic syndrome by integrated bioinformatics analysis and machine learning by Jian Huang, Lu Wang, Jiangfei Zhou, Tianming Dai, Weicong Zhu, Tianrui Wang, Hongde Wang, Yingze Zhang

“…The limma package was used to identify differentially expressed genes (DEGs), and weighted gene coexpression network analysis (WGCNA) screened gene modules, and machine learning algorithms, such as random forest (RF), support vector machine (SVM), generalised linear model (GLM), and extreme gradient boosting (XGB), were employed. …”
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Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning by V. Vigna, T. F. G. G. Cova, A. A. C. C. Pais, E. Sicilia

“…The model is efficient, fast, and resource-light, using decision tree-based algorithms that provide interpretable results. …”
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The impact of a coach-guided personalized depression risk communication program on the risk of major depressive episode: study protocol for a randomized controlled trial by JianLi Wang, Cindy Feng, Mohammad Hajizadeh, Alain Lesage

“…Built upon the research on risk prediction modeling and risk communication, we developed a coach-guided, personalized depression risk communication tool (PDRC) for sharing information about individualized depression risk and evidence-based self-help strategies. …”
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A Combined Deep CNN: LSTM with a Random Forest Approach for Breast Cancer Diagnosis by Almas Begum, V. Dhilip Kumar, Junaid Asghar, D. Hemalatha, G. Arulkumaran

“…Computer-aided diagnosis (CAD) has minimum intervention of humans and produces more accurate results than humans. It will be a difficult and long task that depends on the expertise of pathologists. …”
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Evaluation of three commercial rapid immunoassays for the diagnosis of Clostridioides difficile infection by Hannes Bjarki Vigfússon, Theresa Ennefors, Torbjörn Norén, Martin Sundqvist

“…The C. diff Quik Chek Complete performed the best of the three immunoassays, and when used in combination with NAAT, is a viable option for the laboratory diagnosis of CDI.IMPORTANCELaboratory diagnosis of Clostridioides difficile infection is complex, and current guidelines recommend a two-step diagnostic algorithm with a sensitive screening test and a more specific confirmatory test. …”
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Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning by Tiantian Yu, Tiantian Yu, Tiantian Yu, Guiying Wang, Guiying Wang, Guiying Wang, Xia Xu, Xia Xu, Xia Xu, Jianying Yan, Jianying Yan, Jianying Yan

“…In the final step, we validated the significant hub gene using independent external datasets, the hypoxia model of the HTR-8/SVneo cell line, and human placental tissue samples.ResultsAt last, leptin (LEP) was identified as a core gene through screening and was found to be upregulated. …”
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