Predicting sleep quality among college students during COVID-19 lockdown using a LASSO-based neural network model by Lufeng Chen, Qingquan Chen, Zhimin Huang, Ling Yao, Jiajing Zhuang, Haibin Lu, Yifu Zeng, Jimin Fan, Ailing Song, Yixiang Zhang

“…A total of eight significant predictors finally identified by the LASSO algorithm was incorporated into prediction models. …”
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Predicting distant metastasis of bladder cancer using multiple machine learning models: a study based on the SEER database with external validation by Xin Chang Zou, Xue Peng Rao, Jian Biao Huang, Jie Zhou, Hai Chao Chao, Tao Zeng

“…Features were filtered using the least absolute shrinkage and selection operator (LASSO) regression algorithm. Based on the significant features identified, three ML algorithms were utilized to develop prediction models: logistic regression, support vector machine (SVM), and linear discriminant analysis (LDA). …”
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A machine learning model revealed that exosome small RNAs may participate in the development of breast cancer through the chemokine signaling pathway by Jun-luan Mo, Xi Li, Lin Lei, Ji Peng, Xiong-shun Liang, Hong-hao Zhou, Zhao-qian Liu, Wen-xu Hong, Ji-ye Yin

“…This study utilized machine learning models to screen for key exosome small RNAs and analyzed and validated them. …”
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Integrative analysis of signaling and metabolic pathways, immune infiltration patterns, and machine learning-based diagnostic model construction in major depressive disorder by Lei Tang, Liling Wu, Mengqin Dai, Nian Liu, Lu liu

“…By comparing the enrichment results across the five datasets, we found that the cell-killing signaling pathway was consistently present in the enriched signaling pathways of all datasets, suggesting that this pathway may play a crucial role in the pathogenesis of MDD. The random forest algorithm (AUC = 0.788) was selected as the optimal algorithm from 113 machine learning algorithms, leading to the development of a robust and predictive MDD algorithm, highlighting the important role of NPL in MDD. …”
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Development of a Predictive Model for Metabolic Syndrome Using Noninvasive Data and its Cardiovascular Disease Risk Assessments: Multicohort Validation Study by Jin-Hyun Park, Inyong Jeong, Gang-Jee Ko, Seogsong Jeong, Hwamin Lee

“…Five machine learning algorithms were compared, and the best-performing model was selected based on the area under the receiver operating characteristic curve. …”
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A novel method to predict the haemoglobin concentration after kidney transplantation based on machine learning: prediction model establishment and method optimization by Songping He, Xiangxi Li, Fangyu Peng, Jiazhi Liao, Xia Lu, Hui Guo, Xin Tan, Yanyan Chen

“…A classification prediction model for the haemoglobin concentration after kidney transplantation was constructed. …”
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Optimisation Study of Investment Decision-Making in Distribution Networks of New Power Systems—Based on a Three-Level Decision-Making Model by Wanru Zhao, Ziteng Liu, Rui Zhang, Mai Lu, Wenhui Zhao

“…Next, the Pearson correlation coefficient is employed to screen key influencing factors, and in conjunction with the grey MG(1,1) model and the support vector machine algorithm, precise forecasting of the investment scale is achieved. …”
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An interpretable machine learning model based on computed tomography radiomics for predicting programmed death ligand 1 expression status in gastric cancer by Lihuan Dai, Jinxue Yin, Xin Xin, Chun Yao, Yongfang Tang, Xiaohong Xia, Yuanlin Chen, Shuying Lai, Guoliang Lu, Jie Huang, Purong Zhang, Jiansheng Li, Xiangguang Chen, Xi Zhong

“…After feature reduction and selection, 11 ML algorithms were employed to develop predictive models, and their performance in predicting PD-L1 expression status was evaluated using areas under receiver operating characteristic curves (AUCs). …”
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Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis by Yaqiong Tian, Xuan Zhou, Mi Tian, Lijun Ren, Ruyi Zou, Hanyi Jiang, Miaomiao Xie, Mei Huang, Jingjing Ding, Yin Liu, Jingyu Chen, Min Cao, Hourong Cai

“…COX regression and LASSO algorithm were used to screen featured characteristics. …”
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Single-cell transcriptomics and machine learning unveil ferroptosis features in tumor-associated macrophages: Prognostic model and therapeutic strategies for lung adenocarcinoma by Ting Ji, Ting Ji, Juanli Jiang, Juanli Jiang, Xin Wang, Xin Wang, Kai Yang, Kai Yang, Shaojin Wang, Shaojin Wang, Bin Pan, Bin Pan

“…Using the GeneCards ferroptosis gene set (1515 genes), ferroptosis-related differentially expressed genes in macrophages were screened. Eight machine learning algorithms (LASSO, SVM, XGBoost, etc.) were leveraged to identify prognostic genes and build a Cox regression risk model. …”
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Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method by Sam Chidi Ibeneme, Eunice Odoh, Nweke Martins, Georgian Chiaka Ibeneme

“…Abstract Background Falls are a common problem experienced by people living with HIV yet predictive models specific to this population remain underdeveloped. …”
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Development of a machine learning prognostic model for early prediction of scrub typhus progression at hospital admission based on clinical and laboratory features by Youguang Lu, Zixu Wang, Junhu Wang, Yingqing Mao, Chuanshen Jiang, Jinpiao Wu, Haizhou Liu, Haiming Yi, Chao Chen, Wei Guo, Liguan Liu, Yong Qi

“…Eighteen objective clinical and laboratory features collected at admission were screened using various feature selection algorithms, and used to construct models based on six machine learning algorithms.Results The model based on Gradient Boosting Decision Tree using 14 features screened by Recursive Feature Elimination was evaluated as the optimal one. …”
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Preoperative prediction of recurrence risk factors in operable cervical cancer based on clinical-radiomics features by Xue Du, Xue Du, Chunbao Chen, Lu Yang, Yu Cui, Min Li

“…Logistic regression algorithms were used to construct a fusion clinical-radiomics model to visualize nomograms. …”
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Analysis of immune characteristics and inflammatory mechanisms in COPD patients: a multi-layered study combining bulk and single-cell transcriptome analysis and machine learning by Changjin Wei, Yongfeng Zhu, Caiming Chen, Feipeng Li, Li Zheng

“…Inflammatory-related COPD feature genes were selected using Lasso regression and random forest algorithms, and a COPD risk prediction model was constructed. …”
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Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression by Li-Hong Wu, Liu Yang, Xiang-Xu Wang, Shuang Bai, Xi Yan, Jing Wei, Jun Wang, Fei Tian

“…The CIBERSORT algorithm was utilized to analyze immune cell infiltration. …”
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Glypican-3 regulated epithelial mesenchymal transformation-related genes in osteosarcoma: based on comprehensive tumor microenvironment profiling by Jiaming Zhang, Wei Wang

“…The least absolute shrinkage and selection operator (LASSO) algorithm was applied to screen candidate genes for developing a prognostic model. …”
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Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

“…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. Machine learning algorithms were used to screen for the hub RA-RF differential expression genes, and then a Logistic Regression (LR) model was constructed. …”
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Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research by Fan Jiang, Fan Jiang, Fan Jiang, Yanhua Liu, Linsheng Li, Linsheng Li, Ruizi Ni, Ruizi Ni, Yajing An, Yajing An, Yufeng Li, Yufeng Li, Lingxia Zhang, Wenping Gong

“…A Naive Bayes (NB) model incorporating these two markers demonstrated robust diagnostic performance: training set AUC: median = 0.8572 (inter-quartile range 0.8002, 0.8708), validation AUC = 0.5719 (0.51645, 0.7078), and subgroup AUC = 0.8635 (0.8212, 0.8946).ConclusionOur multicohort analysis established an NB-based diagnostic model utilizing S100A12/S100A8, which maintains diagnostic accuracy across diverse geographic, ethnic, and clinical variables (including HIV co-infection), highlighting its potential for clinical translation in LTBI/ATB differentiation.…”
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Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity by Shan Jin, Junbin Yin, Wei Li, Ni Mao

“…Multiple machine learning algorithms were applied to screen and verify the diagnostic genes of intersection genes. …”
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Machine Learning-Assisted NIR Spectroscopy for Dynamic Monitoring of Leaf Potassium in Korla Fragrant Pear by Mingyang Yu, Weifan Fan, Junkai Zeng, Yang Li, Lanfei Wang, Hao Wang, Feng Han, Jianping Bao

“…By measuring leaf potassium content at the fruit setting, expansion, and maturity stages (decreasing from 1.60% at fruit setting to 1.14% at maturity), this study reveals its dynamic change pattern and establishes a high-precision prediction model by combining near-infrared spectroscopy (NIRS) with machine learning algorithms. …”
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