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HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm.
Published 2025-01-01“…Compared to lengthy medical drugs experimental screening, mathematical models and algorithms show great potential in synergistic drug combinations prediction. …”
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342
Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms
Published 2025-02-01“…This study aims to use computational algorithms to explore the relationship between plasma proteins and AD progression by identifying a panel of plasma proteins that can serve as biomarkers for tracking and diagnosing AD. …”
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A New Fast Sparse Unmixing Algorithm Based on Adaptive Spectral Library Pruning and Nesterov Optimization
Published 2025-01-01“…To address these shortcomings, this article proposes a new fast two-step sparse unmixing algorithm, called NeSU-LP, which is based on adaptive spectral library pruning technology and the Nesterov fast optimization strategy. …”
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Improving routine mental health screening for depression and anxiety in a paediatric lupus clinic: a quality improvement initiative for enhanced mental healthcare
Published 2024-12-01“…Statistical process control charts were used to analyse the outcome measure for percentage of screened patients with cSLE. Patient and caregiver satisfaction surveys were conducted at baseline and after screening as a balancing measure.Interventions MH screening workflow with a referral algorithm was developed with stakeholders. …”
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Predicting Early-Onset Colorectal Cancer in Individuals Below Screening Age Using Machine Learning and Real-World Data: Case Control Study
Published 2025-06-01“…Given the distinct pathology of colon cancer (CC) and rectal cancer (RC), we created separate prediction models for each cancer type with various ML algorithms. …”
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SARS-CoV-2 Prediction Strategy Based on Classification Algorithms from a Full Blood Examination
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351
Integrated Machine Learning Algorithms-Enhanced Predication for Cervical Cancer from Mass Spectrometry-Based Proteomics Data
Published 2025-03-01“…Furthermore, by integrating feature importance values, Shapley values, and local interpretable model-agnostic explanation (LIME) values, we demonstrated that the diagnostic area under the curve (AUC) achieved by our multi-dimensional learning models approached 1, significantly outperforming the diagnostic AUC of single markers derived from the PRIDE database. …”
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Genetics, sex and the use of platelet‐rich plasma influence the development of arthrofibrosis after anterior cruciate ligament reconstruction
Published 2025-01-01“…Abstract Purpose To identify genes and patient factors that are related to the development of arthrofibrosis in patients after anterior cruciate ligament (ACL) reconstruction and to develop a prognostic model. Methods The study included patients diagnosed with ACL injury who underwent ACL reconstruction. …”
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353
Toward Next-Generation Biologically Plausible Single Neuron Modeling: An Evolutionary Dendritic Neuron Model
Published 2025-04-01“…The Dendritic Neuron Model (DNM) offers a more realistic alternative by simulating nonlinear and compartmentalized processing within dendritic branches, enabling efficient and transparent learning. …”
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Economic evaluation of a novel genetic screening test for risk of venous thromboembolism compared with standard of care in women considering combined hormonal contraception in Swit...
Published 2019-11-01“…The risk of having a VTE was derived from the risk algorithm that underpins the PP test. The remaining model inputs relating to population characteristics, costs, health resource use, mortality and utilities were derived from published studies or national sources. …”
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355
The implementation and appraisal of a novel confirmatory HIV-1 testing algorithm in the Microbicides Development Programme 301 Trial (MDP301).
Published 2012-01-01“…This triggered the use of the algorithm which made use of archived serum and Buffy Coat samples. …”
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Non-Destructive Detection of Silage pH Based on Colorimetric Sensor Array Using Extended Color Components and Novel Sensitive Dye Screening Method
Published 2025-01-01“…Extended color components, a novel sensitive dye screening method, and a feature screening method were integrated and applied to enhance pH detection. …”
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358
Analytical screening of polymorphic variants of 20S proteasome genes when planning a study of pathogenetic effects of modification of NFKB1 post-translational processing
Published 2023-06-01“…To calculate the genetic distances between populations, we used the methord of comparing the populations by frequencies of polymorphic marker alleles proposed by Ney, the obtained matrices are illustrated by the method of multidimensional scaling in space using Statistica v.8.0.Results. Discussion of the algorithm and results of analytical screening of polymorphic variants of 14 genes (PSMA1-PSMA7, PSMB1–PSMB7) encoding proteasome subunits 20S. …”
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359
Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation
Published 2025-05-01“…Although more data were available to populate the screening population model, there was substantial uncertainty across all models. …”
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Recent advances in AI-based toxicity prediction for drug discovery
Published 2025-07-01“…The advent of computational approaches has accelerated a shift toward in silico modeling, virtual screening, and, notably, artificial intelligence (AI) to identify potential toxicities earlier in the pipeline. …”
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