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1081
Identification of anoikis-related genes classification patterns and immune infiltration characterization in chronic rhinosinusitis with nasal polyps based on machine learning
Published 2025-08-01“…Immune cell infiltration was analysed using the CIBERSORT algorithm. CRSwNP samples were classified via consensus clustering. …”
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1082
Identification of novel serum lipid metabolism potential markers and metabolic pathways for oral cancer: a population-based study
Published 2025-01-01“…The disease classification model, constructed using a KNN algorithm with 13 metabolites selected through LASSO screening, achieved the best performance, with an AUC of 0.978 (0.955-1.000). …”
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1083
A nicotinamide metabolism-related gene signature for predicting immunotherapy response and prognosis in lung adenocarcinoma patients
Published 2025-02-01“…Four independent prognostic NMRGs (GJB3, CPA3, DKK1, KRT6A) were screened and used to construct a RiskScore model, which exhibited a strong predictive performance. …”
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1084
Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium
Published 2025-04-01“…We employed several machine learning algorithms, including least absolute shrinkage and selection operator and support vector machine–recursive feature elimination, to screen for key genes. …”
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1085
Diagnostic Value of F-FDG PET/CT Radiomics in Lymphoma: A Systematic Review and Meta-Analysis
Published 2025-05-01“…Six meta-regressions were conducted on study performance, considering sample size, image modality, region of interest (ROI) selection, ROI segmentation, radiomics mode, and algorithms. Results In total, 20 studies classified as type 2a or above according to the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement were included for this systematic review and meta-analysis. …”
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1086
Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma
Published 2025-06-01“…The Lasso, Cox, and Step machine learning algorithms were used to construct and screen the optimal risk assessment prognostic model. …”
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1087
Machine learning based identification of anoikis related gene classification patterns and immunoinfiltration characteristics in diabetic nephropathy
Published 2025-05-01“…In addition, seven key genes, including PDK4, S100A8, HTRA1, CHI3L1, WT1, CDKN1B, and EGF, were screened by machine learning algorithm. Most of these genes exhibited low expression in renal tissue of DN patients and positive correlation with neutrophils, and their expressions were verified in an external dataset cell model. …”
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1088
GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma
Published 2025-05-01“…We screened differential genes (DEGs) in the immune and stromal components, and then screened modular genes by the WGCNA algorithm, which were intersected with DEGs and incorporated into the LASSO-COX regression model. …”
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1089
InvarNet: Molecular property prediction via rotation invariant graph neural networks
Published 2024-12-01“…Predicting molecular properties is crucial in drug synthesis and screening, but traditional molecular dynamics methods are time-consuming and costly. …”
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1090
Multi-Omics and Experimental Validation Identify GPX7 and Glutathione-Associated Oxidative Stress as Potential Biomarkers in Ischemic Stroke
Published 2025-05-01“…Multidimensional feature screening using unsupervised consensus clustering and a series of machine learning algorithms led to the identification of the signature gene <i>GPX7</i>. …”
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1091
Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning
Published 2025-01-01“…The model is efficient, fast, and resource-light, using decision tree-based algorithms that provide interpretable results. …”
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1092
The impact of a coach-guided personalized depression risk communication program on the risk of major depressive episode: study protocol for a randomized controlled trial
Published 2024-12-01“…Built upon the research on risk prediction modeling and risk communication, we developed a coach-guided, personalized depression risk communication tool (PDRC) for sharing information about individualized depression risk and evidence-based self-help strategies. …”
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1093
Utilizing Multi-omics analysis to elucidate the role of mitochondrial gene defects in Gastric cancer progression.
Published 2025-01-01“…Additionally, both the ssGSEA algorithm and the CIBERSORT algorithm were utilized to evaluate changes and effects in immunological characteristics during gastric cancer pathogenesis.…”
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1094
Improving synergistic drug combination prediction with signature-based gene expression features in oncology
Published 2025-07-01“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
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1095
Accuracy and interpretability of smartwatch electrocardiogram for early detection of atrial fibrillation: A systematic review and meta‐analysis
Published 2025-06-01“…Methods Data derived from indexed literature in the Scopus, Scilit, PubMed, Google Scholar, Web of Science, IEEE, and Cochrane Library databases (as of June 1, 2024) were systematically screened and extracted. The quantitative synthesis was performed using a two‐level mixed‐effects logistic regression model, as well as a proportional analysis with Freeman‐Tukey double transformation on a restricted maximum‐likelihood model. …”
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1096
Nitrogen content estimation of apple trees based on simulated satellite remote sensing data
Published 2025-07-01“…Support Vector Machine (SVM) and Backpropagation Neural Network (BPNN) algorithms were used to construct and screen the optimal models for apple tree nitrogen content estimation.ResultsResults showed that visible light, red edge, near-infrared, and yellow edge bands were sensitive bands for estimating apple tree nitrogen content. …”
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1097
Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway
Published 2024-12-01“…We screened 84 differentially expressed genes (DEGs) and performed the functional enrichment analysis. …”
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1098
WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer
Published 2025-04-01“…Furthermore, a machine learning algorithm was used to screen for core genes and construct a diagnostic model, which was then validated in an external validation dataset. …”
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1099
The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy
Published 2025-01-01“…Then, a new staging that included TNM and SOSI based on RPA algorithms was produced. In terms of prognostication, the RPA model performed significantly better than TNM classification.ConclusionSOSI is a simple and useful score based on available SOS-related indices. …”
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1100
Machine learning identification of key genes in cardioembolic stroke and atherosclerosis: their association with pan-cancer and immune cells
Published 2025-07-01“…Two machine learning algorithms, Least Absolute Shrinkage and Selection Operator (LASSO) regression and Support Vector Machine Recursive Feature Elimination (SVM-RFE), were used to screen for overlapping FRDEGs in CS and AS. …”
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